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The problem of reconstructing strings from their substring spectra has a long history and in its most simple incarnation asks for determining under which conditions the spectrum uniquely determines the string. We study the problem of coded…

Information Theory · Computer Science 2019-04-24 Ryan Gabrys , Olgica Milenkovic

In the paper, the Levenshtein's sequence reconstruction problem is considered in the case where at most $t$ substitution errors occur in each of the $N$ channels and the decoder outputs a list of length $\mathcal{L}$. Moreover, it is…

Information Theory · Computer Science 2022-11-17 Ville Junnila , Tero Laihonen , Tuomo Lehtilä

Consider a binary word being transmitted through a communication channel that introduces deletable errors where each bit of the word is either retained, flipped, erased or deleted. The simplest code for correcting \emph{all} possible…

Information Theory · Computer Science 2018-05-03 Ghurumuruhan Ganesan

DNA synthesis is considered as one of the most expensive components in current DNA storage systems. In this paper, focusing on a common synthesis machine, which generates multiple DNA strands in parallel following a fixed supersequence,we…

Information Theory · Computer Science 2025-05-13 Yajuan Liu , Tolga M. Duman

Motivated by applications in in-vivo DNA storage, we study codes for correcting duplications. A reverse-complement duplication of length $k$ is the insertion of the reversed and complemented copy of a substring of length $k$ adjacent to its…

Information Theory · Computer Science 2026-02-03 Yubo Sun , Gennian Ge

Transmit a codeword $x$, that belongs to an $(\ell-1)$-deletion-correcting code of length $n$, over a $t$-deletion channel for some $1\le \ell\le t<n$. Levenshtein, in 2001, proposed the problem of determining $N(n,\ell,t)+1$, the minimum…

Information Theory · Computer Science 2021-11-09 Van Long Phuoc Pham , Keshav Goyal , Han Mao Kiah

This paper concerns non-overlapping codes, block codes motivated by synchronisation and DNA-based storage applications. Most existing constructions of these codes do not account for the restrictions posed by the physical properties of…

Information Theory · Computer Science 2025-02-05 Lidija Stanovnik , Miha Moškon , Miha Mraz

The central problem in sequence reconstruction is to find the minimum number of distinct channel outputs required to uniquely reconstruct the transmitted sequence. According to Levenshtein's work in 2001, this number is determined by the…

Information Theory · Computer Science 2025-02-14 Wentu Song , Kui Cai , Tony Q. S. Quek

The problem of storing large amounts of information safely for a long period of time has become essential. One of the most promising new data storage mediums are the polymer-based data storage systems, like the DNA-storage system. These…

Information Theory · Computer Science 2025-04-21 Ville Junnila , Tero Laihonen , Tuomo Lehtilä

We study the amount of reliable information that can be stored in a DNA-based storage system with noisy sequencing, where each codeword is composed of short DNA molecules. We analyze a concatenated coding scheme, where the outer code is…

Information Theory · Computer Science 2026-05-19 Ran Tamir , Nir Weinberger , Albert Guillén i Fàbregas

The sequence reconstruction problem involves a model where a sequence is transmitted over several identical channels. This model investigates the minimum number of channels required for the unique reconstruction of the transmitted sequence.…

Information Theory · Computer Science 2025-04-30 Zhaojun Lan , Yubo Sun , Wenjun Yu , Gennian Ge

Binary neural networks (BNNs) have received ever-increasing popularity for their great capability of reducing storage burden as well as quickening inference time. However, there is a severe performance drop compared with real-valued…

Machine Learning · Computer Science 2023-02-07 Sheng Xu , Yanjing Li , Teli Ma , Mingbao Lin , Hao Dong , Baochang Zhang , Peng Gao , Jinhu Lv

Nanopore sequencing, superior to other sequencing technologies for DNA storage in multiple aspects, has recently attracted considerable attention. Its high error rates, however, demand thorough research on practical and efficient coding…

Information Theory · Computer Science 2024-06-21 Anisha Banerjee , Yonatan Yehezkeally , Antonia Wachter-Zeh , Eitan Yaakobi

DNA storage has emerged as a promising solution for large-scale and long-term data preservation. Among various error types, insertions are the most frequent errors occurring in DNA sequences, where the inserted symbol is often identical or…

Information Theory · Computer Science 2026-04-07 Hengfeng Liu , Chunming Tang , Cuiling Fan

Regenerating codes allow distributed storage systems to recover from the loss of a storage node while transmitting the minimum possible amount of data across the network. We present a systematic computer search for optimal systematic…

Information Theory · Computer Science 2009-10-14 Daniel Cullina , Alexandros G. Dimakis , Tracey Ho

The construction of asymmetric error correcting codes is a topic that was studied extensively, however, the existing approach for code construction assumes that every codeword should tolerate $t$ asymmetric errors. Our main observation is…

Information Theory · Computer Science 2012-09-05 Hongchao Zhou , Anxiao , Jiang , Jehoshua Bruck

In this paper, we present a novel communication channel, called the absorption channel, inspired by information transmission in neurons. Our motivation comes from in-vivo nano-machines, emerging medical applications, and brain-machine…

Information Theory · Computer Science 2023-02-21 Zuo Ye , Ohad Elishco

DNA storage has emerged as an important area of research. The reliability of DNA storage system depends on designing the DNA strings (called DNA codes) that are sufficiently dissimilar. In this work, we introduce DNA codes that satisfy a…

Information Theory · Computer Science 2022-11-28 Krishna Gopal Benerjee , Sourav Deb , Manish K Gupta

Most DNA sequencing technologies are based on the shotgun paradigm: many short reads are obtained from random unknown locations in the DNA sequence. A fundamental question, studied in arXiv:1203.6233, is what read length and coverage depth…

Information Theory · Computer Science 2022-02-09 Aditya Narayan Ravi , Alireza Vahid , Ilan Shomorony

Due to their sequential nature, traditional DNA synthesis methods are expensive in terms of time and resources. They also fabricate multiple copies of the same strand, introducing redundancy. This redundancy can be leveraged to enhance the…

Information Theory · Computer Science 2025-10-29 Frederik Walter , Yonatan Yehezkeally