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Objective: Molecular testing (MT) classifies cytologically indeterminate thyroid nodules as benign or malignant with high sensitivity but low positive predictive value (PPV), only using molecular profiles, ignoring ultrasound (US) imaging…

The rapid development of diagnostic technologies in healthcare is leading to higher requirements for physicians to handle and integrate the heterogeneous, yet complementary data that are produced during routine practice. For instance, the…

Machine Learning · Computer Science 2023-01-30 Can Cui , Haichun Yang , Yaohong Wang , Shilin Zhao , Zuhayr Asad , Lori A. Coburn , Keith T. Wilson , Bennett A. Landman , Yuankai Huo

Melanoma detection is vital for early diagnosis and effective treatment. While deep learning models on dermoscopic images have shown promise, they require specialized equipment, limiting their use in broader clinical settings. This study…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Volodymyr Sydorskyi , Igor Krashenyi , Oleksii Yakubenko

Segmentation of nodules in thyroid ultrasound imaging plays a crucial role in the detection and treatment of thyroid cancer. However, owing to the diversity of scanner vendors and imaging protocols in different hospitals, the automatic…

Image and Video Processing · Electrical Eng. & Systems 2024-01-23 Xuewei Li , Yaqiao Zhu , Jie Gao , Xi Wei , Ruixuan Zhang , Yuan Tian , ZhiQiang Liu

In recent years, many mammographic image analysis methods have been introduced for improving cancer classification tasks. Two major issues of mammogram classification tasks are leveraging multi-view mammographic information and…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Thanh-Huy Nguyen , Quang Hien Kha , Thai Ngoc Toan Truong , Ba Thinh Lam , Ba Hung Ngo , Quang Vinh Dinh , Nguyen Quoc Khanh Le

Thyroid cancer is among the most common cancers in the United States. Thyroid nodules are frequently detected through ultrasound (US) imaging, and some require further evaluation via fine-needle aspiration (FNA) biopsy. Despite its…

A reliable evaluation of surgical difficulty can improve the success of the treatment for rectal cancer and the current evaluation method is based on clinical data. However, more data about rectal cancer can be collected with the…

Machine Learning · Computer Science 2025-06-24 Wei Zhang , Zi Wang , Hanwen Zhou , Zhaohong Deng , Weiping Ding , Yuxi Ge , Te Zhang , Yuanpeng Zhang , Kup-Sze Choi , Shitong Wang , Shudong Hu

Prostate cancer represents a major threat to health. Early detection is vital in reducing the mortality rate among prostate cancer patients. One approach involves using multi-modality (CT, MRI, US, etc.) computer-aided diagnosis (CAD)…

Image and Video Processing · Electrical Eng. & Systems 2024-07-10 Rui Jin , Derun Li , Dehui Xiang , Lei Zhang , Hailing Zhou , Fei Shi , Weifang Zhu , Jing Cai , Tao Peng , Xinjian Chen

Background: Thyroid volumetry is crucial in diagnosis, treatment and monitoring of thyroid diseases. However, conventional thyroid volumetry with 2D ultrasound is highly operator-dependent. This study compares 2D ultrasound and tracked 3D…

AI-driven precision oncology has the transformative potential to reshape cancer treatment by leveraging the power of AI models to analyze the interaction between complex patient characteristics and their corresponding treatment outcomes.…

Risk stratification (characterization) of tumors from radiology images can be more accurate and faster with computer-aided diagnosis (CAD) tools. Tumor characterization through such tools can also enable non-invasive cancer staging,…

Computer Vision and Pattern Recognition · Computer Science 2019-01-21 Sarfaraz Hussein , Pujan Kandel , Candice W. Bolan , Michael B. Wallace , Ulas Bagci

We present a tool for resolution recovery in multimodal clinical magnetic resonance imaging (MRI). Such images exhibit great variability, both biological and instrumental. This variability makes automated processing with neuroimaging…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Mikael Brudfors , Yael Balbastre , Parashkev Nachev , John Ashburner

Artificial intelligence based radiomics models for thyroid ultrasound (US) often achieve strong diagnostic performance but remain difficult to interpret, limiting clinical trust and adoption. We developed and validated an interpretable…

Machine learning (ML) for diagnosis of thyroid nodules on ultrasound is an active area of research. However, ML tools require large, well-labelled datasets, the curation of which is time-consuming and labor-intensive. The purpose of our…

Image and Video Processing · Electrical Eng. & Systems 2023-05-05 Jikai Zhang , Maciej M. Mazurowski , Brian C. Allen , Benjamin Wildman-Torbiner

In this study, we develop a new CAD system for accurate thyroid cancer classification with emphasis on feature extraction. Prior studies have shown that thyroid texture is important for segregating the thyroid ultrasound images into…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Saurabh Saini , Kapil Ahuja , Marc C. Steinbach , Thomas Wick

Manual segmentation of medical images (e.g., segmenting tumors in CT scans) is a high-effort task that can be accelerated with machine learning techniques. However, selecting the right segmentation approach depends on the evaluation…

Computer Vision and Pattern Recognition · Computer Science 2023-02-09 Seyed M. R. Modaresi , Aomar Osmani , Mohammadreza Razzazi , Abdelghani Chibani

Objectives: The purpose is to apply a previously validated deep learning algorithm to a new thyroid nodule ultrasound image dataset and compare its performances with radiologists. Methods: Prior study presented an algorithm which is able to…

Image and Video Processing · Electrical Eng. & Systems 2023-05-08 Jingxi Weng , Benjamin Wildman-Tobriner , Mateusz Buda , Jichen Yang , Lisa M. Ho , Brian C. Allen , Wendy L. Ehieli , Chad M. Miller , Jikai Zhang , Maciej A. Mazurowski

Timely and accurate diagnosis is crucial in addressing the global rise in thyroid cancer, ensuring effective treatment strategies and improved patient outcomes. We present an intelligent classification method that couples an Adaptive…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Nada Bouchekout , Abdelkrim Boukabou , Morad Grimes , Yassine Habchi , Yassine Himeur , Hamzah Ali Alkhazaleh , Shadi Atalla , Wathiq Mansoor

This work is motivated by multimodality breast cancer imaging data, which is quite challenging in that the signals of discrete tumor-associated microvesicles (TMVs) are randomly distributed with heterogeneous patterns. This imposes a…

Machine Learning · Statistics 2019-03-22 Xiwei Tang , Xuan Bi , Annie Qu

Weakly-supervised methods typically guided the pixel-wise training by comparing the predictions to single-level labels containing diverse segmentation-related information at once, but struggled to represent delicate feature differences…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Jianning Chi , Zelan Li , Huixuan Wu , Wenjun Zhang , Ying Huang