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The development of reliable and extensible molecular mechanics (MM) force fields -- fast, empirical models characterizing the potential energy surface of molecular systems -- is indispensable for biomolecular simulation and computer-aided…

We introduce a system-independent method to derive effective atomic C$_6$ coefficients and polarizabilities in molecules and materials purely from charge population analysis. This enables the use of dispersion-correction schemes in…

Materials Science · Physics 2016-09-05 Martin Stöhr , Georg S. Michelitsch , John C. Tully , Karsten Reuter , Reinhard J. Maurer

Despite decades of research, the modeling of moving contact lines has remained a formidable challenge in fluid dynamics whose resolution will impact numerous industrial, biological, and daily life applications. On the one hand, molecular…

Soft Condensed Matter · Physics 2018-11-09 E. R. Smith , P. E. Theodorakis , R. V. Craster , O. K. Matar

In CFD simulations of two-phase flows, accurate drag force modeling is essential for predicting particle dynamics. However, a generally valid formulation is lacking, as all available drag force correlations have been established for…

Fluid Dynamics · Physics 2023-02-08 Gizem Ozler , Mustafa Demircioglu , Holger Grosshans

Long ranged electrostatic interactions are time consuming to calculate in molecular dynamics and Monte-Carlo simulations. We introduce an algorithmic framework for simulating charged particles which modifies the dynamics so as to allow…

Statistical Mechanics · Physics 2009-09-07 A. C. Maggs , V. Rossetto

We present a new scalable algorithm for short-range molecular dynamics simulations on distributed memory MIMD multicomputer based on a message-passing multi-cell approach. We have implemented the algorithm on the Connection Machine 5 (CM-5)…

comp-gas · Physics 2008-02-03 D. M. Beazley , P. S. Lomdahl

A current challenge in atomistic machine learning is that of efficiently predicting the response of the electron density under electric fields. We address this challenge with symmetry-adapted kernel functions that are specifically derived…

Materials Science · Physics 2025-02-26 Mariana Rossi , Kevin Rossi , Alan M. Lewis , Mathieu Salanne , Andrea Grisafi

We propose a new molecular simulation framework that combines the transferability, robustness and chemical flexibility of an ab initio method with the accuracy and efficiency of a machine learned force field. The key to achieve this mix is…

Computational Physics · Physics 2020-01-08 Sebastian Dick , Marivi Fernandez-Serra

The implementation of Molecular Dynamics (MD) on FPGAs has received substantial attention. Previous work, however, has consisted of either proof-of-concept implementations of components, usually the range-limited force; full systems, but…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-05-15 Chen Yang , Tong Geng , Tianqi Wang , Rushi Patel , Qingqing Xiong , Ahmed Sanaullah , Jiayi Sheng , Charles Lin , Vipin Sachdeva , Woody Sherman , Martin C. Herbordt

The strengths and short-comings of the point-dipole model for polar fluids of spherical molecules are illustrated by considering the physically more relevant case of extended dipoles formed by two opposite charges $\pm q$ separated by a…

Statistical Mechanics · Physics 2009-11-10 V. Ballenegger , J. P. Hansen

Polymorphs in molecular crystals are often very close in energy, yet they may possess markedly different physical and chemical properties. The understanding and prediction of polymorphism is of paramount importance for a variety of…

The fluctuations of the charge on an electrode contain information on the microscopic correlations within the adjacent fluid and their effect on the electronic properties of the interface. We investigate these fluctuations using molecular…

This paper deals with the formulation, calibration, and validation of a Lattice Discrete Particle Model (LDPM) for the simulation of the pressure-dependent inelastic response of granular rocks. LDPM is formulated in the framework of…

Materials Science · Physics 2016-05-23 Shiva Esna Ashari , Giuseppe Buscarnera , Gianluca Cusatis

Analytic first and second derivatives of the energy are developed for the fragment molecular orbital method interfaced with molecular mechanics in the electrostatic embedding scheme at the level of Hartree-Fock and density functional…

Chemical Physics · Physics 2020-05-19 Hiroya Nakata , Dmitri G. Fedorov

We review our recently developed electronic structure calculation methods used for the dynamics of large-scale solids or liquids with an efficient algorithm for large scale simultaneous linear equations. The electronic structure calculation…

Materials Science · Physics 2011-02-02 T. Fujiwara , S. Yamamoto , T. Hoshi , S. Nishino , H. Teng , T. Sogabe , S. -L. Zhang , M. Ikeda , M. Nakashima , N. Watanabe

The distribution of the electric microfield at a charged particle moving in a two-component plasma is calculated. The theoretical approximations are obtained via the parameter integration technique and using the screened pair approximation…

Plasma Physics · Physics 2015-06-26 J. Ortner , I. Valuev , W. Ebeling

Molecular Dynamics (MD) simulations play a central role in physics-driven drug discovery. MD applications often use the Particle Mesh Ewald (PME) algorithm to accelerate electrostatic force computations, but efficient parallelization has…

Hardware Architecture · Computer Science 2021-04-06 Lawrence C. Stewart , Carlo Pascoe , Brian W. Sherman , Martin Herbordt , Vipin Sachdeva

Mn enrichment at dislocations in Fe-Mn alloys due to segregation and spinodal decomposition along the dislocation line is studied via modeling and experimental characterization. To model these phenomena, both finite-deformation microscopic…

Proteins have been empirically linked to memory. If memory relates to protein structure, then each conformation would_functionally_ code only one bit, making it difficult to explain large memories. Nor is there a simple way to relate memory…

General Physics · Physics 2011-07-22 C. K. Raju

Three dimensional implementations of liquid state theories offer an efficient alternative to computer simulations for the atomic-level description of aqueous solutions in complex environments. In this context, we present a (classical)…

Chemical Physics · Physics 2013-02-13 Guillaume Jeanmairet , Maximilien Levesque , Rodolphe Vuilleumier , Daniel Borgis
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