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Data augmentation is one of the most effective techniques to improve the generalization performance of deep neural networks. Yet, despite often facing limited data availability in medical image analysis, it is frequently underutilized. This…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Adam Tupper , Christian Gagné

Deep learning has become a popular tool for medical image analysis, but the limited availability of training data remains a major challenge, particularly in the medical field where data acquisition can be costly and subject to privacy…

Image and Video Processing · Electrical Eng. & Systems 2024-06-11 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Su Ruan

Deep Learning has thrived on the emergence of biomedical big data. However, medical datasets acquired at different institutions have inherent bias caused by various confounding factors such as operation policies, machine protocols,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-15 Yundong Zhang , Hang Wu , Huiye Liu , Li Tong , May D Wang

Deep neural networks are increasingly being used to detect and diagnose medical conditions using medical imaging. Despite their utility, these models are highly vulnerable to adversarial attacks and distribution shifts, which can affect…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Josué Martínez-Martínez , Olivia Brown , Mostafa Karami , Sheida Nabavi

Recently, we have witnessed great progress in the field of medical imaging classification by adopting deep neural networks. However, the recent advanced models still require accessing sufficiently large and representative datasets for…

Computer Vision and Pattern Recognition · Computer Science 2020-10-30 Haoliang Li , YuFei Wang , Renjie Wan , Shiqi Wang , Tie-Qiang Li , Alex C. Kot

Medical image segmentation models are often trained on curated datasets, leading to performance degradation when deployed in real-world clinical settings due to mismatches between training and test distributions. While data augmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-05-16 Puru Vaish , Felix Meister , Tobias Heimann , Christoph Brune , Jelmer M. Wolterink

In this paper, for the first time, we propose an evaluation method for deep learning models that assesses the performance of a model not only in an unseen test scenario, but also in extreme cases of noise, outliers and ambiguous input data.…

Computer Vision and Pattern Recognition · Computer Science 2018-04-03 Magdalini Paschali , Sailesh Conjeti , Fernando Navarro , Nassir Navab

Deep learning-based models in medical imaging often struggle to generalize effectively to new scans due to data heterogeneity arising from differences in hardware, acquisition parameters, population, and artifacts. This limitation presents…

Image and Video Processing · Electrical Eng. & Systems 2023-08-09 Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

Deep learning based methods for image reconstruction are state-of-the-art for a variety of imaging tasks. However, neural networks often perform worse if the training data differs significantly from the data they are applied to. For…

Image and Video Processing · Electrical Eng. & Systems 2024-08-08 Kang Lin , Reinhard Heckel

In this paper, we explore and compare multiple solutions to the problem of data augmentation in image classification. Previous work has demonstrated the effectiveness of data augmentation through simple techniques, such as cropping,…

Computer Vision and Pattern Recognition · Computer Science 2017-12-14 Luis Perez , Jason Wang

Despite their massive size, successful deep artificial neural networks can exhibit a remarkably small difference between training and test performance. Conventional wisdom attributes small generalization error either to properties of the…

Machine Learning · Computer Science 2017-02-28 Chiyuan Zhang , Samy Bengio , Moritz Hardt , Benjamin Recht , Oriol Vinyals

As deep neural networks grow in size, from thousands to millions to billions of weights, the performance of those networks becomes limited by our ability to accurately train them. A common naive question arises: if we have a system with…

Machine Learning · Computer Science 2018-05-29 Nathan O. Hodas , Panos Stinis

We study the recently introduced stability training as a general-purpose method to increase the robustness of deep neural networks against input perturbations. In particular, we explore its use as an alternative to data augmentation and…

Machine Learning · Computer Science 2019-11-14 Jan Laermann , Wojciech Samek , Nils Strodthoff

Deep neural networks have emerged as very successful tools for image restoration and reconstruction tasks. These networks are often trained end-to-end to directly reconstruct an image from a noisy or corrupted measurement of that image. To…

Image and Video Processing · Electrical Eng. & Systems 2021-06-30 Zalan Fabian , Reinhard Heckel , Mahdi Soltanolkotabi

Deep learning models usually suffer from domain shift issues, where models trained on one source domain do not generalize well to other unseen domains. In this work, we investigate the single-source domain generalization problem: training a…

Computer Vision and Pattern Recognition · Computer Science 2023-04-24 Cheng Ouyang , Chen Chen , Surui Li , Zeju Li , Chen Qin , Wenjia Bai , Daniel Rueckert

Deep learning-based computer-aided diagnosis is gradually deployed to review and analyze medical images. However, this paradigm is restricted in real-world clinical applications due to the poor robustness and generalization. The issue is…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yurong Chen

Purpose: The segmentation of brain tumors is one of the most active areas of medical image analysis. While current methods perform superhuman on benchmark data sets, their applicability in daily clinical practice has not been evaluated. In…

Image and Video Processing · Electrical Eng. & Systems 2020-12-17 Sabine Müller , Joachim Weickert , Norbert Graf

Generalization is the ability of a model to predict on unseen domains and is a fundamental task in machine learning. Several generalization bounds, both theoretical and empirical have been proposed but they do not provide tight bounds .In…

Machine Learning · Computer Science 2021-01-19 Sumukh Aithal K , Dhruva Kashyap , Natarajan Subramanyam

Deep learning models often struggle to maintain generalizability in medical imaging, particularly under domain-fracture scenarios where distribution shifts arise from varying imaging techniques, acquisition protocols, patient populations,…

Machine Learning · Computer Science 2025-08-15 Furkan Pala , Islem Rekik

While deep neural networks can attain good accuracy on in-distribution test points, many applications require robustness even in the face of unexpected perturbations in the input, changes in the domain, or other sources of distribution…

Machine Learning · Computer Science 2022-10-12 Marvin Zhang , Sergey Levine , Chelsea Finn
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