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Aligning the entire genome of an organism is a compute-intensive task. Pre-alignment filters substantially reduce computation complexity by filtering potential alignment locations. The base-count filter successfully removes over 68% of the…

Systems and Control · Electrical Eng. & Systems 2022-06-03 Marcel Khalifa , Rotem Ben-Hur , Ronny Ronen , Orian Leitersdorf , Leonid Yavits , Shahar Kvatinsky

Modern Machine Learning (ML) training on large-scale datasets is a very time-consuming workload. It relies on the optimization algorithm Stochastic Gradient Descent (SGD) due to its effectiveness, simplicity, and generalization performance.…

Hardware Architecture · Computer Science 2024-09-30 Steve Rhyner , Haocong Luo , Juan Gómez-Luna , Mohammad Sadrosadati , Jiawei Jiang , Ataberk Olgun , Harshita Gupta , Ce Zhang , Onur Mutlu

The integration of deep learning in medical imaging has shown great promise for enhancing diagnostic, therapeutic, and research outcomes. However, applying universal models across multiple modalities remains challenging due to the inherent…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Yixin Chen , Lin Gao , Yajuan Gao , Rui Wang , Jingge Lian , Xiangxi Meng , Yanhua Duan , Leiying Chai , Hongbin Han , Zhaoping Cheng , Zhaoheng Xie

We present a novel approach for accelerating convolutions during inference for CPU-based architectures. The most common method of computation involves packing the image into the columns of a matrix (im2col) and performing general matrix…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Amir Ofir , Gil Ben-Artzi

This paper presents a novel symbolic algorithm for the Maximal End Component (MEC) decomposition of a Markov Decision Process (MDP). The key idea behind our algorithm INTERLEAVE is to interleave the computation of Strongly Connected…

Logic in Computer Science · Computer Science 2025-07-22 Suguman Bansal , Ramneet Singh

Analog computing based on memristor technology is a promising solution to accelerating the inference phase of deep neural networks (DNNs). A fundamental problem is to map an arbitrary matrix to a memristor crossbar array (MCA) while…

Emerging Technologies · Computer Science 2019-11-28 Baogang Zhang , Necati Uysal , Deliang Fan , Rickard Ewetz

The widespread adoption of cloud-based solutions introduces privacy and security concerns. Techniques such as homomorphic encryption (HE) mitigate this problem by allowing computation over encrypted data without the need for decryption.…

Cryptography and Security · Computer Science 2024-12-13 Mpoki Mwaisela , Joel Hari , Peterson Yuhala , Jämes Ménétrey , Pascal Felber , Valerio Schiavoni

We introduce a fusion of GPU accelerated primal heuristics for Mixed Integer Programming. Leveraging GPU acceleration enables exploration of larger search regions and faster iterations. A GPU-accelerated PDLP serves as an approximate LP…

Optimization and Control · Mathematics 2025-10-31 Akif Çördük , Piotr Sielski , Alice Boucher , Kumar Aatish

Particle-in-Cell (PIC) simulations spend most of their execution time on particle--grid interactions, where fine-grained atomic updates become a major bottleneck on traditional many-core CPUs. Recent CPU architectures integrate specialized…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-14 Yizhuo Rao , Xingjian Cui , Jiabin Xie , Shangzhi Pang , Guangnan Feng , Jinhui Wei , Zhiguang Chen , Yutong Lu

Memristive devices hold promise to improve the scale and efficiency of machine learning and neuromorphic hardware, thanks to their compact size, low power consumption, and the ability to perform matrix multiplications in constant time.…

Emerging Technologies · Computer Science 2024-08-14 Zhenming Yu , Ming-Jay Yang , Jan Finkbeiner , Sebastian Siegel , John Paul Strachan , Emre Neftci

Probabilistic reasoning is an essential tool for robust decision-making systems because of its ability to explicitly handle real-world uncertainty, constraints and causal relations. Consequently, researchers are developing hybrid models by…

Hardware Architecture · Computer Science 2021-03-02 Nimish Shah , Laura I. Galindez Olascoaga , Wannes Meert , Marian Verhelst

Processor-in-Memory (PIM) overlays and new redesigned reconfigurable tile fabrics have been proposed to eliminate the von Neumann bottleneck and enable processing performance to scale with BRAM capacity. The performance of these FPGA-based…

Hardware Architecture · Computer Science 2024-10-08 MD Arafat Kabir , Tendayi Kamucheka , Nathaniel Fredricks , Joel Mandebi , Jason Bakos , Miaoqing Huang , David Andrews

Computing-in-memory (CIM) has attracted significant attentions in recent years due to its massive parallelism and low power consumption. However, current CIM designs suffer from large area overhead of small CIM macros and bad programmablity…

Hardware Architecture · Computer Science 2022-05-04 Shu-Hung Kuo , Tian-Sheuan Chang

Markov chain Monte Carlo (MCMC) is a widely used sampling method in modern artificial intelligence and probabilistic computing systems. It involves repetitive random number generations and thus often dominates the latency of probabilistic…

Hardware Architecture · Computer Science 2023-12-12 Yihan Fu , Daijing Shi , Anjunyi Fan , Wenshuo Yue , Yuchao Yang , Ru Huang , Bonan Yan

Kernel matrix-vector multiplication (KMVM) is a foundational operation in machine learning and scientific computing. However, as KMVM tends to scale quadratically in both memory and time, applications are often limited by these…

Numerical Analysis · Mathematics 2025-02-25 Robert Hu , Siu Lun Chau , Dino Sejdinovic , Joan Alexis Glaunès

Bit-serial Processing-In-Memory (PIM) is an attractive paradigm for accelerator architectures, for parallel workloads such as Deep Learning (DL), because of its capability to achieve massive data parallelism at a low area overhead and…

Hardware Architecture · Computer Science 2023-11-21 Aman Arora , Jian Weng , Siyuan Ma , Tony Nowatzki , Lizy K. John

Transformers are the driving force behind today's Large Language Models (LLMs), serving as the foundation for their performance and versatility. Yet, their compute and memory costs grow with sequence length, posing scalability challenges…

Matrix extensions have emerged as an essential feature in modern CPUs to address the surging demands of AI workloads. However, existing designs often incur substantial hardware and software design overhead. Tight coupling with the CPU…

Hardware Architecture · Computer Science 2026-04-14 Jinpeng Ye , Chongxi Wang , Wenqing Li , Bin Yuan , Shiyi Wang , Fenglu Zhang , Junyu Yue , Jianan Xie , Yunhao Ye , Haoyu Deng , Yingkun Zhou , Xin Cheng , Fuxin Zhang , Jian Wang

Deep neural networks (DNNs) have revolutionized the field of artificial intelligence and have achieved unprecedented success in cognitive tasks such as image and speech recognition. Training of large DNNs, however, is computationally…

Computing-in-memory (CIM) has been demonstrated across various memory technologies, ranging from memristive crossbars performing analog dot-product computations to large-scale digital bitwise operations in commodity DRAM and other proposed…

Hardware Architecture · Computer Science 2025-04-25 João Paulo Cardoso de Lima , Benjamin Franklin Morris , Asif Ali Khan , Jeronimo Castrillon , Alex K. Jones