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Computational models lie at the intersection of basic neuroscience and healthcare applications because they allow researchers to test hypotheses \textit{in silico} and predict the outcome of experiments and interactions that are very hard…

Neurons and Cognition · Quantitative Biology 2020-09-18 Katharina Glomb , Joana Cabral , Anna Cattani , Alberto Mazzoni , Ashish Raj , Benedetta Franceschiello

Electroencephalography (EEG) monitors ---by either intrusive or noninvasive electrodes--- time and frequency variations and spectral content of voltage fluctuations or waves, known as brain rhythms, which in some way uncover activity during…

Neurons and Cognition · Quantitative Biology 2019-03-13 Javier A. Galadí , Joaquín J. Torres , J. Marro

Traveling waves of neural activity are widely observed in the brain, but their precise computational function remains unclear. One prominent hypothesis is that they enable the transfer and integration of spatial information across neural…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Mozes Jacobs , Roberto C. Budzinski , Lyle Muller , Demba Ba , T. Anderson Keller

This paper introduces a novel approach for modelling time-varying connectivity in neuroimaging data, focusing on the slow fluctuations in synaptic efficacy that mediate neuronal dynamics. Building on the framework of Dynamic Causal…

Neurons and Cognition · Quantitative Biology 2024-12-05 Johan Medrano , Karl J. Friston , Peter Zeidman

We present a new paradigm in the study of brain mental dynamics on the basis of the stable transient activity neural networks observed in experiments. This new approach is in contrast to traditional system analysis usually adopted in…

Adaptation and Self-Organizing Systems · Physics 2009-09-08 Mikhail I. Rabinovich , Mehmet K. Muezzinoglu

Dynamical systems theory has long provided a foundation for understanding evolving phenomena across scientific domains. Yet, the application of this theory to complex real-world systems remains challenging due to issues in mathematical…

Machine Learning · Computer Science 2024-11-05 Samuel A. Moore , Brian P. Mann , Boyuan Chen

Patients with epilepsy can manifest short, sub-clinical epileptic "bursts" in addition to full-blown clinical seizures. We believe the relationship between these two classes of events---something not previously studied…

Machine Learning · Statistics 2014-07-29 Drausin F. Wulsin , Emily B. Fox , Brian Litt

Neural mass models describe the mean-field dynamics of populations of neurons. In this work we illustrate how fundamental ideas of physics, such as energy and conserved quantities, can be explored for such models. We show that…

Neurons and Cognition · Quantitative Biology 2025-09-15 Daniele Andrean , Morten Gram Pedersen

Being permanently confronted with an uncertain world, brains have faced evolutionary pressure to represent this uncertainty in order to respond appropriately. Often, this requires visiting multiple interpretations of the available…

Mean field models (MFMs) of cortical tissue incorporate salient features of neural masses to model activity at the population level. One of the common aspects of MFM descriptions is the presence of a high dimensional parameter space…

Dynamical Systems · Mathematics 2015-05-19 Federico Frascoli , Lennaert van Veen , Ingo Bojak , David T J Liley

Biological neural networks are notoriously hard to model due to their stochastic behavior and high dimensionality. We tackle this problem by constructing a dynamical model of both the expectations and covariances of the fractions of active…

Neurons and Cognition · Quantitative Biology 2025-02-25 Vincent Painchaud , Patrick Desrosiers , Nicolas Doyon

The study of dynamical systems defined on complex networks provides a natural framework with which to investigate myriad features of neural dynamics, and has been widely undertaken. Typically, however, networks employed in theoretical…

Neurons and Cognition · Quantitative Biology 2013-02-22 Reuben O'Dea , Jonathan J. Crofts , Marcus Kaiser

Understanding of the onset and generic mechanisms of transitions between distinct patterns of activity in realistic models of individual neurons and neural networks presents a fundamental challenge for the theory of applied dynamical…

Neurons and Cognition · Quantitative Biology 2020-07-14 Marina L. Kolomiets , Andrey L. Shilnikov

The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…

Neurons and Cognition · Quantitative Biology 2017-03-03 Jannis Schuecker , Maximilian Schmidt , Sacha J. van Albada , Markus Diesmann , Moritz Helias

The human brain is a complex dynamical system which displays a wide range of macroscopic and mesoscopic patterns of neural activity, whose mechanistic origin remains poorly understood. Whole-brain modelling allows us to explore candidate…

Neurons and Cognition · Quantitative Biology 2025-04-25 Cristiana Dimulescu , Ronja Strömsdörfer , Agnes Flöel , Klaus Obermayer

Computational modeling of neurodynamical systems often deploys neural networks and symbolic dynamics. A particular way for combining these approaches within a framework called vector symbolic architectures leads to neural automata. An…

Neural and Evolutionary Computing · Computer Science 2023-02-07 Jone Uria-Albizuri , Giovanni Sirio Carmantini , Peter beim Graben , Serafim Rodrigues

Neural circuits are able to perform computations under very diverse conditions and requirements. The required computations impose clear constraints on their fine-tuning: a rapid and maximally informative response to stimuli in general…

Neurons and Cognition · Quantitative Biology 2019-10-22 Jens Wilting , Jonas Dehning , Joao Pinheiro Neto , Lucas Rudelt , Michael Wibral , Johannes Zierenberg , Viola Priesemann

Simplified models are a necessary steppingstone for understanding collective neural network dynamics, in particular the transitions between different kinds of behavior, whose universality can be captured by such models, without prejudice.…

Chaotic Dynamics · Physics 2022-10-25 Rashid V. Williams-García , Stam Nicolis

Large-scale neuroscience is generating rich datasets across animals, brain areas and behavioral contexts, yet our modeling efforts remains fragmented across isolated experiments. We argue that understanding behavior requires integrative…

Stylized models of the neurodynamics that underpin sensory motor control in animals are proposed and studied. The voluntary motions of animals are typically initiated by high level intentions created in the primary cortex through a…

Systems and Control · Electrical Eng. & Systems 2021-10-12 John Baillieul , Zexin Sun