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Efficient deployment of large language models (LLMs) requires extreme quantization, forcing a critical trade-off between low-bit efficiency and performance. Residual binarization enables hardware-friendly, matmul-free inference by stacking…

Artificial Intelligence · Computer Science 2026-05-19 Youngcheon You , Banseok Lee , Minseop Choi , Seonyoung Kim , Hyochan Chong , Changdong Kim , Youngmin Kim , Dongkyu Kim

In supervised machine learning, feature selection plays a very important role by potentially enhancing explainability and performance as measured by computing time and accuracy-related metrics. In this paper, we investigate a method for…

Machine Learning · Computer Science 2024-02-02 Raisa Islam , Subhasish Mazumdar , Rakibul Islam

Today there exists no shortage of outlier detection algorithms in the literature, yet the complementary and critical problem of unsupervised outlier model selection (UOMS) is vastly understudied. In this work we propose ELECT, a new…

Machine Learning · Computer Science 2022-11-04 Yue Zhao , Sean Zhang , Leman Akoglu

Active learning with strong and weak labelers considers a practical setting where we have access to both costly but accurate strong labelers and inaccurate but cheap predictions provided by weak labelers. We study this problem in the…

Understanding the molecular processes that drive cellular life is a fundamental question in biological research. Ambitious programs have gathered a number of molecular datasets on large populations. To decipher the complex cellular…

Genomics · Quantitative Biology 2023-03-22 Myriam Bontonou , Anaïs Haget , Maria Boulougouri , Jean-Michel Arbona , Benjamin Audit , Pierre Borgnat

One of the main obstacles of adopting digital pathology is the challenge of efficient processing of hyperdimensional digitized biopsy samples, called whole slide images (WSIs). Exploiting deep learning and introducing compact WSI…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Azam Asilian Bidgoli , Shahryar Rahnamayan , Taher Dehkharghanian , Abtin Riasatian , H. R. Tizhoosh

We aim to enhance ophthalmologists' decision-making when diagnosing the Neovascular Age-Related Macular Degeneration (nAMD). We developed three tools to analyze Optical Coherence Tomography Angiography images: (1) extracting biomarkers such…

Image and Video Processing · Electrical Eng. & Systems 2026-01-28 MAria Simona Tivadar , Ioana Damian , Adrian Groza , Simona Delia Nicoara

Biomedical data is filled with continuous real values; these values in the feature set tend to create problems like underfitting, the curse of dimensionality and increase in misclassification rate because of higher variance. In response,…

Artificial Intelligence · Computer Science 2020-04-17 Deepak Singh , Dilip Singh Sisodia , Pradeep Singh

Advancing the discovery of prognostic cancer biomarkers is crucial for comprehending disease mechanisms, refining treatment plans, and improving patient outcomes. This study introduces Weighted Gene Topological Data Analysis (WGTDA), an…

Quantitative Methods · Quantitative Biology 2024-02-15 Ndivhuwo Nyase , Lebohang Mashatola , Aviwe Kohlakala , Kahn Rhrissorrakrai , Stephanie Muller

Biclustering is an unsupervised machine-learning approach aiming to cluster rows and columns simultaneously in a data matrix. Several biclustering algorithms have been proposed for handling numeric datasets. However, real-world data mining…

Machine Learning · Computer Science 2024-08-26 Adán José-García , Julie Jacques , Clément Chauvet , Vincent Sobanski , Clarisse Dhaenens

A computational challenge to validate the candidate disease genes identified in a high-throughput genomic study is to elucidate the associations between the set of candidate genes and disease phenotypes. The conventional gene set enrichment…

Genomics · Quantitative Biology 2011-02-22 TaeHyun Hwang , Wei Zhang , Maoqiang Xie , Rui Kuang

Many prediction problems on social networks, from recommendations to anomaly detection, can be approached by modeling network data as a sequence of relational events and then leveraging the resulting model for prediction. Conditional logit…

Social and Information Networks · Computer Science 2020-06-18 Jan Overgoor , George Pakapol Supaniratisai , Johan Ugander

The discovery of disease subtypes is an essential step for developing precision medicine, and disease subtyping via omics data has become a popular approach. While promising, subtypes obtained from existing approaches are not necessarily…

Quantitative Methods · Quantitative Biology 2022-03-01 Lingsong Meng , Dorina Avram , George Tseng , Zhiguang Huo

The aim of Active Learning is to select the most informative samples from an unlabelled set of data. This is useful in cases where the amount of data is large and labelling is expensive, such as in machine vision or medical imaging. Two…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Julien Combes , Alexandre Derville , Jean-François Coeurjolly

During the last decades, many methods for the analysis of functional data including classification methods have been developed. Nonetheless, there are issues that have not been adressed satisfactorily by currently available methods, as, for…

Methodology · Statistics 2017-02-08 Karen Fuchs , Wolfgang Pößnecker , Gerhard Tutz

Recent advances in Large Language Models (LLMs) have raised urgent concerns about LLM-generated text authenticity, prompting regulatory demands for reliable identification mechanisms. Although watermarking offers a promising solution,…

Computation and Language · Computer Science 2025-08-26 Xiaoyan Feng , He Zhang , Yanjun Zhang , Leo Yu Zhang , Shirui Pan

We propose a general approach to handle data contaminations that might disrupt the performance of feature selection and estimation procedures for high-dimensional linear models. Specifically, we consider the co-occurrence of mean-shift and…

Methodology · Statistics 2021-06-23 Luca Insolia , Francesca Chiaromonte , Runze Li , Marco Riani

In this paper, we explore the challenges associated with biomarker identification for diagnosis purpose in biomedical experiments, and propose a novel approach to handle the above challenging scenario via the generalization of the Dantzig…

Methodology · Statistics 2023-11-14 Jing-Wen Huang , Yan-Hong Chen , Frederick Kin Hing Phoa , Yan-Han Lin , Shau-Ping Lin

Gene prioritization (identifying genes potentially associated with a biological process) is increasingly tackled with Artificial Intelligence. However, existing methods struggle with the high dimensionality and incomplete labelling of…

Lyme disease is a rapidly growing illness that remains poorly understood within the medical community. Critical questions about when and why patients respond to treatment or stay ill, what kinds of treatments are effective, and even how to…

Computers and Society · Computer Science 2020-09-22 Joshua Vendrow , Jamie Haddock , Deanna Needell , Lorraine Johnson
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