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As a common strategy of contagious disease containment, lockdowns will inevitably weaken the economy. The ongoing COVID-19 pandemic underscores the trade-off arising from public health and economic cost. An optimal lockdown policy to…

Optimization and Control · Mathematics 2022-01-26 Qianqian Ma , Yang-Yu Liu , Alex Olshevsky

The evolution of the COVID-19 epidemic has been accompanied by accumulating evidence on the underlying epidemiological parameters. Hence there is potential for models providing mid-term forecasts of the epidemic trajectory using such…

Applications · Statistics 2020-11-10 Peter Congdon

It is well recognized that population heterogeneity plays an important role in the spread of epidemics. While individual variations in social activity are often assumed to be persistent, i.e. constant in time, here we discuss the…

Populations and Evolution · Quantitative Biology 2021-02-22 Alexei V. Tkachenko , Sergei Maslov , Tong Wang , Ahmed Elbanna , George N. Wong , Nigel Goldenfeld

The recent COVID-19 pandemic has shown that when the reproduction number is high and there are no proper measurements in place, the number of infected people can increase dramatically in a short time, producing a phenomenon that many…

Populations and Evolution · Quantitative Biology 2022-09-20 Jonathan A. Chávez Casillas

This paper presents the assessment of time-dependent national-level restrictions and control actions and their effects in fighting the COVID-19 pandemic. By analysing the transmission dynamics during the first wave of COVID-19 in the…

Populations and Evolution · Quantitative Biology 2021-02-04 Ton Duc Do , Meei Mei Gui , Kok Yew Ng

In this paper, we present a Distributionally Robust Markov Decision Process (DRMDP) approach for addressing the dynamic epidemic control problem. The Susceptible-Exposed-Infectious-Recovered (SEIR) model is widely used to represent the…

Optimization and Control · Mathematics 2023-06-27 Jun Song , William Yang , Chaoyue Zhao

Stochastic epidemic models which incorporate interactions between space and human mobility are a key tool to inform prioritisation of outbreak control to appropriate locations. However, methods for fitting such models to national-level…

Motivated by the rapid spread of COVID-19 all across the globe, we have performed simulations of a system dynamic epidemic spread model in different possible situations. The simulation, not only captures the model dynamic of the spread of…

Populations and Evolution · Quantitative Biology 2020-04-02 Kashif Zia , Umar Farooq

Repeated decision-making problems under uncertainty may arise in the health policy context, such as infectious disease control for COVID-19 and other epidemics. These problems may sometimes be effectively solved using Markov decision…

Optimization and Control · Mathematics 2024-11-28 Suyanpeng Zhang , Sze-chuan Suen

Combating an epidemic entails finding a plan that describes when and how to apply different interventions, such as mask-wearing mandates, vaccinations, school or workplace closures. An optimal plan will curb an epidemic with minimal loss of…

Machine Learning · Computer Science 2023-06-08 Anh Mai , Nikunj Gupta , Azza Abouzied , Dennis Shasha

We tackle limitations of ordinary differential equation-driven Susceptible-Infections-Removed (SIR) models and their extensions that have recently be employed for epidemic nowcasting and forecasting. In particular, we deal with challenges…

Computation · Statistics 2026-02-10 Angelos Alexopoulos , Paul Birrell , Daniela De Angelis

COVID-19 will be a continuous threat to human population despite having a few vaccines at hand until we reach the endemic state through natural herd immunity and total immunization through universal vaccination. However, the vaccine acts as…

Populations and Evolution · Quantitative Biology 2022-08-26 V. R. Saiprasad , R. Gopal , V. K. Chandrasekar , M. Lakshmanan

During the Covid-19 pandemic, most governments across the world imposed policies like lock-down of public spaces and restrictions on people's movements to minimize the spread of the virus through physical contact. However, such policies…

Multiagent Systems · Computer Science 2021-09-10 Gaurav Suryawanshi , Varun Madhavan , Adway Mitra , Partha Pratim Chakrabarti

Epidemic spreading can be suppressed by the introduction of containment measures such as social distancing and lock downs. Yet, when such measures are relaxed, new epidemic waves and infection cycles may occur. Here we explore this issue in…

Physics and Society · Physics 2020-12-07 Fabio Caccioli , Daniele De Martino

The rapid spread of the Coronavirus SARS-2 is a major challenge that led almost all governments worldwide to take drastic measures to respond to the tragedy. Chief among those measures is the massive lockdown of entire countries and cities,…

Computers and Society · Computer Science 2020-06-15 Salah Ghamizi , Renaud Rwemalika , Lisa Veiber , Maxime Cordy , Tegawende F. Bissyande , Mike Papadakis , Jacques Klein , Yves Le Traon

The first mitigation response to the Covid-19 pandemic was to limit person-to-person interaction as much as possible. This was implemented by the temporary closing of many workplaces and people were required to follow social distancing.…

Physics and Society · Physics 2020-06-17 Parul Maheshwari , Réka Albert

As the world fights to contain and control the spread of the Novel Coronavirus, countries are imposing severe measures from restrictions on travel and social gatherings to complete lockdowns. Lockdowns, though effective in controlling the…

Physics and Society · Physics 2020-05-19 Saket Saurabh , Ayush Trivedi , Nithilaksh P. Lokesh , Bhagyashree Gaikwad

In this paper we conduct a simulation study of the spread of an epidemic like COVID-19 with temporary immunity on finite spatial and non-spatial network models. In particular, we assume that an epidemic spreads stochastically on a…

Physics and Society · Physics 2021-12-16 Tim Hulshof , Joost Jorritsma , Júlia Komjáthy

Since late 2019 the novel coronavirus, also known as COVID-19, has caused a pandemic that persists. This paper shows how a continuous-time Markov chain model for the spread of COVID-19 can be used to explain, and justify to undergraduate…

Applications · Statistics 2022-06-22 Armine Bagyan , Donald Richards

We study the impact on the epidemiological dynamics of a class of restrictive measures that are aimed at reducing the number of contacts of individuals who have a higher risk of being infected with a transmittable disease. Such measures are…

Populations and Evolution · Quantitative Biology 2021-09-15 Giacomo Cacciapaglia , Stefan Hohenegger , Francesco Sannino
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