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Computer-aided early diagnosis of Alzheimer's disease (AD) and its prodromal form mild cognitive impairment (MCI) based on structure Magnetic Resonance Imaging (sMRI) has provided a cost-effective and objective way for early prevention and…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Xin Zhang , Liangxiu Han , Wenyong Zhu , Liang Sun , Daoqiang Zhang

Machine learning has shown promise for automatic detection of Alzheimer's disease (AD) through speech; however, efforts are hampered by a scarcity of data, especially in languages other than English. We propose a method to learn a…

Computation and Language · Computer Science 2019-06-04 Bai Li , Yi-Te Hsu , Frank Rudzicz

Training automatic speech recognition (ASR) models increasingly relies on decentralized federated learning to ensure data privacy and accessibility, producing multiple local models that require effective merging. In hybrid ASR systems,…

Computation and Language · Computer Science 2026-03-06 Mengze Hong , Yi Gu , Di Jiang , Hanlin Gu , Chen Jason Zhang , Lu Wang , Zhiyang Su

We uncover an underlying bias present in the audio recordings produced from the picture description task of the Pitt corpus, the largest publicly accessible database for Alzheimer's Disease (AD) detection research. Even by solely utilizing…

Audio and Speech Processing · Electrical Eng. & Systems 2024-06-12 Yin-Long Liu , Rui Feng , Jia-Hong Yuan , Zhen-Hua Ling

The early diagnosis of Alzheimer's Disease (AD) through non invasive methods remains a significant healthcare challenge. We present NeuroXVocal, a novel dual-component system that not only classifies but also explains potential AD cases…

In this paper, we propose a natural language processing architecture that can handle tasks that previously required two models as one model. With a single model, we analyze the language patterns and conversational context of Alzheimer's…

Computation and Language · Computer Science 2022-11-16 Park Jun Yeong , Shin Su Jong , Choi Chang Hwan , Lee Jung Jae , Choi Sang-il

Self-supervised learning (SSL) based speech foundation models have been applied to a wide range of ASR tasks. However, their application to dysarthric and elderly speech via data-intensive parameter fine-tuning is confronted by in-domain…

Audio and Speech Processing · Electrical Eng. & Systems 2024-07-22 Shujie Hu , Xurong Xie , Mengzhe Geng , Zengrui Jin , Jiajun Deng , Guinan Li , Yi Wang , Mingyu Cui , Tianzi Wang , Helen Meng , Xunying Liu

Diffusion MRI is the modality of choice to study alterations of white matter. In past years, various works have used diffusion MRI for automatic classification of AD. However, classification performance obtained with different approaches is…

ASR Error Detection (AED) models aim to post-process the output of Automatic Speech Recognition (ASR) systems, in order to detect transcription errors. Modern approaches usually use text-based input, comprised solely of the ASR…

Computation and Language · Computer Science 2022-10-27 Zorik Gekhman , Dina Zverinski , Jonathan Mallinson , Genady Beryozkin

We model Alzheimer's disease (AD) progression by combining differential equations (DEs) and reinforcement learning (RL) with domain knowledge. DEs provide relationships between some, but not all, factors relevant to AD. We assume that the…

Machine Learning · Computer Science 2021-11-03 Krishnakant V. Saboo , Anirudh Choudhary , Yurui Cao , Gregory A. Worrell , David T. Jones , Ravishankar K. Iyer

Despite rapid advances in large language models (LLMs), their integration with traditional supervised machine learning (ML) techniques that have proven applicability to medical data remains underexplored. This is particularly true for…

Computation and Language · Computer Science 2025-05-28 Yuxin Zhu , Yuting Guo , Noah Marchuck , Abeed Sarker , Yun Wang

We propose a first step toward multilingual end-to-end automatic speech recognition (ASR) by integrating knowledge about speech articulators. The key idea is to leverage a rich set of fundamental units that can be defined "universally"…

Audio and Speech Processing · Electrical Eng. & Systems 2023-09-19 Hao Yen , Sabato Marco Siniscalchi , Chin-Hui Lee

Noise robustness is critical when applying automatic speech recognition (ASR) in real-world scenarios. One solution involves the used of speech enhancement (SE) models as the front end of ASR. However, neural network-based (NN-based) SE…

The application of machine learning algorithms to the diagnosis and analysis of Alzheimer's disease (AD) from multimodal neuroimaging data is a current research hotspot. It remains a formidable challenge to learn brain region information…

Image and Video Processing · Electrical Eng. & Systems 2022-08-11 Yongcheng Zong , Changhong Jing , Qiankun Zuo

Deep transformer models have been used to detect linguistic anomalies in patient transcripts for early Alzheimer's disease (AD) screening. While pre-trained neural language models (LMs) fine-tuned on AD transcripts perform well, little…

Computation and Language · Computer Science 2025-06-09 Zhecheng Sheng , Xiruo Ding , Brian Hur , Changye Li , Trevor Cohen , Serguei Pakhomov

Prior works have investigated the use of articulatory features as complementary representations for automatic speech recognition (ASR), but their use was largely confined to shallow acoustic models. In this work, we revisit articulatory…

Audio and Speech Processing · Electrical Eng. & Systems 2025-10-13 Ahmed Adel Attia , Jing Liu , Carol Espy Wilson

This paper presents a speech intelligibility model based on automatic speech recognition (ASR), combining phoneme probabilities from deep neural networks (DNN) and a performance measure that estimates the word error rate from these…

Early and accurate diagnosis of Alzheimer's disease (AD) and its prodromal period mild cognitive impairment (MCI) is essential for the delayed disease progression and the improved quality of patients'life. The emerging computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2021-07-29 Fan Zhang , Bo Pan , Pengfei Shao , Peng Liu , Shuwei Shen , Peng Yao , Ronald X. Xu

Deep learning has shown outstanding performance in identifying intricate structures in complex high-dimensional data, especially in the domain of computer vision. The application of deep learning to early detection and automated…

Image and Video Processing · Electrical Eng. & Systems 2019-08-22 Taeho Jo , Kwangsik Nho , Andrew J. Saykin

Recent publications on automatic-speech-recognition (ASR) have a strong focus on attention encoder-decoder (AED) architectures which tend to suffer from over-fitting in low resource scenarios. One solution to tackle this issue is to…

Computation and Language · Computer Science 2021-07-14 Nick Rossenbach , Mohammad Zeineldeen , Benedikt Hilmes , Ralf Schlüter , Hermann Ney