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Pathology image segmentation is crucial in computational pathology for analyzing histological features relevant to cancer diagnosis and prognosis. However, current methods face major challenges in clinical applications due to limited…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Zhixuan Chen , Junlin Hou , Liqi Lin , Yihui Wang , Yequan Bie , Xi Wang , Yanning Zhou , Ronald Cheong Kin Chan , Hao Chen

Deep convolutional neural networks (CNNs) have shown excellent performance in object recognition tasks and dense classification problems such as semantic segmentation. However, training deep neural networks on large and sparse datasets is…

Computer Vision and Pattern Recognition · Computer Science 2017-12-25 Lorenz Berger , Eoin Hyde , M. Jorge Cardoso , Sebastien Ourselin

Fully supervised segmentation methods require a large training cohort of already segmented images, providing information at the pixel level of each image. We present a method to automatically segment and model pathologies in medical images,…

Computer Vision and Pattern Recognition · Computer Science 2019-08-22 Simon Andermatt , Antal Horváth , Simon Pezold , Philippe Cattin

We aim at segmenting small organs (e.g., the pancreas) from abdominal CT scans. As the target often occupies a relatively small region in the input image, deep neural networks can be easily confused by the complex and variable background.…

Computer Vision and Pattern Recognition · Computer Science 2018-04-10 Qihang Yu , Lingxi Xie , Yan Wang , Yuyin Zhou , Elliot K. Fishman , Alan L. Yuille

Assigning geospatial objects with specific categories at the pixel level is a fundamental task in remote sensing image analysis. Along with rapid development in sensor technologies, remotely sensed images can be captured at multiple spatial…

Computer Vision and Pattern Recognition · Computer Science 2021-11-05 Libo Wang , Ce Zhang , Rui Li , Chenxi Duan , Xiaoliang Meng , Peter M. Atkinson

Brain lesion volume measured on T2 weighted MRI images is a clinically important disease marker in multiple sclerosis (MS). Manual delineation of MS lesions is a time-consuming and highly operator-dependent task, which is influenced by…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Hang Zhang , Jinwei Zhang , Qihao Zhang , Jeremy Kim , Shun Zhang , Susan A. Gauthier , Pascal Spincemaille , Thanh D. Nguyen , Mert R. Sabuncu , Yi Wang

Convolutional neural networks, the state of the art for image segmentation, have been successfully applied to histology images by many computational researchers. However, the translatability of this technology to clinicians and biological…

Image and Video Processing · Electrical Eng. & Systems 2021-01-19 Brendon Lutnick , David Manthey , Pinaki Sarder

Automatic retinal layer segmentation with medical images, such as optical coherence tomography (OCT) images, serves as an important tool for diagnosing ophthalmic diseases. However, it is challenging to achieve accurate segmentation due to…

Image and Video Processing · Electrical Eng. & Systems 2024-04-26 Xiang He , Weiye Song , Yiming Wang , Fabio Poiesi , Ji Yi , Manishi Desai , Quanqing Xu , Kongzheng Yang , Yi Wan

Image segmentation is a fundamental and challenging problem in computer vision with applications spanning multiple areas, such as medical imaging, remote sensing, and autonomous vehicles. Recently, convolutional neural networks (CNNs) have…

Computer Vision and Pattern Recognition · Computer Science 2020-06-24 Ali Hatamizadeh

Conventional scaling of neural networks typically involves designing a base network and growing different dimensions like width, depth, etc. of the same by some predefined scaling factors. We introduce an automated scaling approach…

Machine Learning · Computer Science 2024-02-21 Akash Guna R. T , Arnav Chavan , Deepak Gupta

Biomedical image segmentation plays a significant role in computer-aided diagnosis. However, existing CNN based methods rely heavily on massive manual annotations, which are very expensive and require huge human resources. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2023-01-13 Ruifei Zhang , Sishuo Liu , Yizhou Yu , Guanbin Li

Accurate cancer diagnosis remains a critical challenge in digital pathology, largely due to the gigapixel size and complex spatial relationships present in whole slide images. Traditional multiple instance learning (MIL) methods often…

Computer Vision and Pattern Recognition · Computer Science 2024-04-18 Kechun Liu , Wenjun Wu , Joann G. Elmore , Linda G. Shapiro

Accurate semantic segmentation models typically require significant computational resources, inhibiting their use in practical applications. Recent works rely on well-crafted lightweight models to achieve fast inference. However, these…

Computer Vision and Pattern Recognition · Computer Science 2023-02-20 Danna Xue , Fei Yang , Pei Wang , Luis Herranz , Jinqiu Sun , Yu Zhu , Yanning Zhang

Constructing a multi-modal automatic classification model based on three types of renal biopsy images can assist pathologists in glomerular multi-disease identification. However, the substantial scale difference between transmission…

Computer Vision and Pattern Recognition · Computer Science 2025-12-18 Kaixing Long , Danyi Weng , Yun Mi , Zhentai Zhang , Yanmeng Lu , Jian Geng , Zhitao Zhou , Liming Zhong , Qianjin Feng , Wei Yang , Lei Cao

Convolutional Neural Network(CNN) has been widely used for image recognition with great success. However, there are a number of limitations of the current CNN based image recognition paradigm. First, the receptive field of CNN is generally…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Dong-Qing Zhang

The state-of-the-art object detection and image classification methods can perform impressively on more than 9k and 10k classes, respectively. In contrast, the number of classes in semantic segmentation datasets is relatively limited. This…

Computer Vision and Pattern Recognition · Computer Science 2021-04-09 Shipra Jain , Danda Paudel Pani , Martin Danelljan , Luc Van Gool

Precise and scalable instance segmentation of cell nuclei is essential for computational pathology, yet gigapixel Whole-Slide Images pose major computational challenges. Existing approaches rely on patch-based processing and costly…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Matěj Pekár , Vít Musil , Rudolf Nenutil , Petr Holub , Tomáš Brázdil

Semantic image segmentation is the process of labeling each pixel of an image with its corresponding class. An encoder-decoder based approach, like U-Net and its variants, is a popular strategy for solving medical image segmentation tasks.…

Image and Video Processing · Electrical Eng. & Systems 2020-06-30 Debesh Jha , Michael A. Riegler , Dag Johansen , Pål Halvorsen , Håvard D. Johansen

Towards holistic understanding of 3D scenes, a general 3D segmentation method is needed that can segment diverse objects without restrictions on object quantity or categories, while also reflecting the inherent hierarchical structure. To…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Haiyang Ying , Yixuan Yin , Jinzhi Zhang , Fan Wang , Tao Yu , Ruqi Huang , Lu Fang

Whole-slide images (WSIs) are fundamental for computational pathology, where accurate lesion segmentation is critical for clinical decision making. Existing methods partition WSIs into discrete patches, disrupting spatial continuity and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Yunheng Wu , Wenqi Huang , Liangyi Wang , Masahiro Oda , Yuichiro Hayashi , Daniel Rueckert , Kensaku Mori