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We develop an extension of the time-dependent equation-of-motion formulation of the polarizable continuum model (EOM-TDPCM) to introduce nonequilibrium cavity field effects in quantum mechanical calculations of solvated molecules subject to…

Chemical Physics · Physics 2020-04-17 Gabriel Gil , Silvio Pipolo , Alain Delgado , Carlo Andrea Rozzi , Stefano Corni

Simulations of chemical dynamics are a powerful means for understanding chemistry. However, classical computers struggle to simulate many chemical processes, especially non-adiabatic ones, where the Born-Oppenheimer approximation breaks…

Proton-coupled electron transfer (PCET) is the key step for energy conversion in electrocatalysis. Atomic-scale simulation acts as an indispensable tool to provide a microscopic understanding of PCET. However, consideration of the quantum…

Materials Science · Physics 2024-08-27 Menglin Sun , Bin Jin , Xiaolong Yang , Shenzhen Xu

We present a new method for realizing the adiabatic connection approach in density functional theory, which is based on combining accurate variational quantum Monte Carlo calculations with a constrained optimization of the ground state…

Materials Science · Physics 2015-06-25 Maziar Nekovee , W. M. C. Foulkes , A. J. Williamson , G. Rajagopal , R. J. Needs

In recent years, the quantum Mpemba effect (QME), which occurs when an out-of-equilibrium system reaches equilibrium faster than another that is closer to equilibrium, has attracted significant attention from the scientific community as an…

Quantum Physics · Physics 2026-05-05 Rodrigo F. Saliba , Raphael C. Drumond

Water's phase diagram remains one of the most intricate and challenging benchmarks in molecular modeling. In this study, we compute the phase diagram of water using an Atomic Cluster Expansion (ACE) potential trained on density-functional…

Materials Science · Physics 2026-01-21 Eslam Ibrahim , Yury Lysogorskiy , Ralf Drautz , Pablo Piaggi

Including quantum mechanical effects on the dynamics of nuclei in the condensed phase is challenging, because the complexity of exact methods grows exponentially with the number of quantum degrees of freedom. Efforts to circumvent these…

Chemical Physics · Physics 2015-06-23 Mariana Rossi , Hanchao Liu , Francesco Paesani , Joel Bowman , Michele Ceriotti

Path integral Monte Carlo approach is used to study the coupled quantum dynamics of the electron and nuclei in hydrogen molecule ion. The coupling effects are demonstrated by comparing differences in adiabatic Born--Oppenheimer and…

Chemical Physics · Physics 2008-12-29 I. Kylänpää , M. Leino , T. T. Rantala

Electrochemical interfaces are of fundamental importance in electrocatalysis, batteries, and metal corrosion. Finite-field methods are one of most reliable approaches for modeling electrochemical interfaces in complete cells under realistic…

Chemical Physics · Physics 2025-06-13 Chaoqiang Feng , Bin Jiang

We propose a hybrid variational framework that enhances Neural Quantum States (NQS) with a Normalising Flow-based sampler to improve the expressivity and trainability of quantum many-body wavefunctions. Our approach decouples the sampling…

Quantum Physics · Physics 2025-06-17 Vishal S. Ngairangbam , Michael Spannowsky , Timur Sypchenko

Hydrogen bond symmetrisations in H-bonded systems triggered by pressure induced nuclear quantum effects (NQEs) is a long-known concept1 but experimental evidences in high-pressure ices have remained elusive with conventional methods2,3.…

Materials Science · Physics 2018-09-05 Thomas Meier , Sylvain Petitgirard , Saiana Khandarkhaeva , Leonid Dubrovinsky

An adaptive modeling method (AMM) that couples a deep neural network potential and a classical force field is introduced to address the accuracy-efficiency dilemma faced by the molecular simulation community. The AMM simulated system is…

Chemical Physics · Physics 2018-11-14 Linfeng Zhang , Han Wang , Weinan E

The Equation of State (EoS) of dense nuclear matter remains one of the most compelling open questions in high-energy astrophysics. While static EoS models are increasingly well-constrained by observations of binary neutron star (BNS)…

High Energy Astrophysical Phenomena · Physics 2026-02-23 Ofek Dan , Ofek Birnholtz

A comprehensive microscopic understanding of ambient liquid water is a major challenge for $ab$ $initio$ simulations as it simultaneously requires an accurate quantum mechanical description of the underlying potential energy surface (PES)…

Chemical Physics · Physics 2019-10-28 Hsin-Yu Ko , Linfeng Zhang , Biswajit Santra , Han Wang , Weinan E , Robert A. DiStasio , Roberto Car

DNA is the most important biological molecule, and its hydration contributes essentially to the structure and functions of the double helix. We analyze the microhydration of the individual bases of nucleic acids and their methyl derivatives…

Biological Physics · Physics 2013-02-12 J. Lino , E. González , A. Deriabina , M. Velasco , V. Poltev

A balanced description of both static and dynamic correlations in electronic systems with nearly degenerate low-lying states presents a challenge for multi-configurational methods on classical computers. We present here a quantum algorithm…

Despite the inherently quantum mechanical nature of hydrogen bonding, it is unclear how nuclear quantum effects (NQEs) alter the strengths of hydrogen bonds. With this in mind, we use ab initio path integral molecular dynamics to determine…

Chemical Physics · Physics 2016-11-22 Wei Fang , Ji Chen , Mariana Rossi , Yexin Feng , Xin-Zheng Li , Angelos Michaelides

We investigate relaxation-order inversion, known as the quantum Mpemba effect (QME), in a minimal open many-body system called a one-dimensional four-site Bose--Hubbard chain governed by Lindblad dynamics with local number dephasing.…

Nuclear quantum effects, such as zero-point energy and tunneling, cause significant changes to the structure and dynamics of hydrogen bonded systems such as liquid water. However, due to the current inability to simulate liquid water using…

Chemical Physics · Physics 2015-06-19 Lu Wang , Michele Ceriotti , Thomas E. Markland

A parameterization strategy for molecular models on the basis of force fields is proposed, which allows a rapid development of models for small molecules by using results from quantum mechanical (QM) ab initio calculations and thermodynamic…

Chemical Physics · Physics 2009-04-22 Bernhard Eckl , Jadran Vrabec , Hans Hasse