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The literature manifests that schizophrenia is associated with alterations in brain network connectivity. We investigate whether large-scale Extended Granger Causality (lsXGC) can capture such alterations using resting-state fMRI data. Our…

Neurons and Cognition · Quantitative Biology 2021-01-27 Axel Wismüller , M. Ali Vosoughi

Deep Learning (DL) in neuroimaging has become increasingly relevant for detecting neurological conditions and neurodegenerative disorders. One of the most predominant biomarkers in neuroimaging is represented by brain age, which has been…

Image and Video Processing · Electrical Eng. & Systems 2025-11-20 Carlo Alberto Barbano , Matteo Brunello , Benoit Dufumier , Marco Grangetto

The cerebral cortex is composed of multiple cortical areas that exert a wide variety of brain functions. Although human brain neurons are genetically and areally mosaic, the three-dimensional structural differences between neurons in…

\hspace{2mm} Diffusion-weighted magnetic resonance imaging (dMRI) of the brain offers unique capabilities including noninvasive probing of tissue microstructure and structural connectivity. It is widely used for clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Davood Karimi , Simon K. Warfield

Stroke is a common disabling neurological condition that affects about one-quarter of the adult population over age 25; more than half of patients still have poor outcomes, such as permanent functional dependence or even death, after the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-19 Chia-Ling Tsai , Hui-Yun Su , Shen-Feng Sung , Wei-Yang Lin , Ying-Ying Su , Tzu-Hsien Yang , Man-Lin Mai

As a mental disorder progresses, it may affect brain structure, but brain function expressed in brain dynamics is affected much earlier. Capturing the moment when brain dynamics express the disorder is crucial for early diagnosis. The…

Image and Video Processing · Electrical Eng. & Systems 2019-11-19 Usman Mahmood , Md Mahfuzur Rahman , Alex Fedorov , Zening Fu , Sergey Plis

Single-subject mapping of resting-state brain functional activity to non-imaging phenotypes is a major goal of neuroimaging. The large majority of learning approaches applied today rely either on static representations or on short-term…

Machine Learning · Computer Science 2022-08-09 Ahmed El-Gazzar , Rajat Mani Thomas , Guido Van Wingen

Key features of mental illnesses are reflected in speech. Our research focuses on designing a multimodal deep learning structure that automatically extracts salient features from recorded speech samples for predicting various mental…

Machine Learning · Computer Science 2020-04-15 Habibeh Naderi , Behrouz Haji Soleimani , Stan Matwin

Autism spectrum disorder (ASD) is associated with behavioral and communication problems. Often, functional magnetic resonance imaging (fMRI) is used to detect and characterize brain changes related to the disorder. Recently, machine…

Image and Video Processing · Electrical Eng. & Systems 2020-04-22 Marcel Bengs , Nils Gessert , Alexander Schlaefer

Stroke is a major public health problem, affecting millions worldwide. Deep learning has recently demonstrated promise for enhancing the diagnosis and risk prediction of stroke. However, existing methods rely on costly medical imaging…

Image and Video Processing · Electrical Eng. & Systems 2025-12-17 Saeed Shurrab , Aadim Nepal , Terrence J. Lee-St. John , Nicola G. Ghazi , Bartlomiej Piechowski-Jozwiak , Farah E. Shamout

The increasing access to brain signal data using electroencephalography creates new opportunities to study electrophysiological brain activity and perform ambulatory diagnoses of neuronal diseases. This work proposes a pairwise distance…

Machine Learning · Computer Science 2019-09-09 David Calhas , Enrique Romero , Rui Henriques

Early diagnosis of Alzheimer Diagnostics (AD) is a challenging task due to its subtle and complex clinical symptoms. Deep learning-assisted medical diagnosis using image recognition techniques has become an important research topic in this…

Image and Video Processing · Electrical Eng. & Systems 2024-01-26 Yihao Lin , Ximeng Li , Yan Zhang , Jinshan Tang

Sub-cortical brain structure segmentation in Magnetic Resonance Images (MRI) has attracted the interest of the research community for a long time because morphological changes in these structures are related to different neurodegenerative…

Computer Vision and Pattern Recognition · Computer Science 2018-11-15 Kaisar Kushibar , Sergi Valverde , Sandra Gonzalez-Villa , Jose Bernal , Mariano Cabezas , Arnau Oliver , Xavier Llado

Attention Deficit Hyperactivity Disorder (ADHD) is a highly prevalent neurodevelopmental condition; however, its neurobiological diagnosis remains challenging due to the lack of reliable imaging-based biomarkers, particularly anatomical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Qurat Ul Ain , Alptekin Temizel , Soyiba Jawed

The Disrupted in Schizophrenia Gene 1 (DISC1) plays a role in both neural signalling and development and is associated with schizophrenia, although its links to altered brain structure and function in this disorder are not fully…

Neurons and Cognition · Quantitative Biology 2014-06-10 Xiaohong Gong , Wenlian Lu , Keith M. Kendrick , Weidan Pu , Chu Wang , Li Jin , Guangmin Lu , Zhening Liu , Haihong Liu , Jianfeng Feng

In this paper, we describe our method for classification of brain magnetic resonance (MR) images into different abnormalities and healthy classes based on the deep neural network. We propose our method to detect high and low-grade glioma,…

Computer Vision and Pattern Recognition · Computer Science 2017-08-18 Mina Rezaei , Haojin Yang , Christoph Meinel

Self-supervised deep learning has accelerated 2D natural image analysis but remains difficult to translate into 3D MRI, where data are scarce and pre-trained 2D backbones cannot capture volumetric context. We present a…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Liam Chalcroft , Jenny Crinion , Cathy J. Price , John Ashburner

Bipolar Disorder (BD) is a psychiatric condition diagnosed by repetitive cycles of hypomania and depression. Since diagnosing BD relies on subjective behavioral assessments over a long period, a solid diagnosis based on objective criteria…

Image and Video Processing · Electrical Eng. & Systems 2023-10-12 Masood Hamed Saghayan , Mohammad Hossein Zolfagharnasab , Ali Khadem , Farzam Matinfar , Hassan Rashidi

Brain Functional Networks (BFNs), graph theoretical models of brain activity data, provide a systems perspective of complex functional connectivity within the brain. Neurological disorders are known to have basis in abnormal functional…

Quantitative Methods · Quantitative Biology 2016-08-30 Megha Singh , Rahul Badhwar , Ganesh Bagler

Magnetic resonance imaging~(MRI) have played a crucial role in brain disease diagnosis, with which a range of computer-aided artificial intelligence methods have been proposed. However, the early explorations usually focus on the limited…

Computer Vision and Pattern Recognition · Computer Science 2023-09-14 Jiayu Lei , Lisong Dai , Haoyun Jiang , Chaoyi Wu , Xiaoman Zhang , Yao Zhang , Jiangchao Yao , Weidi Xie , Yanyong Zhang , Yuehua Li , Ya Zhang , Yanfeng Wang
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