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Capturing the semantics of related biological concepts, such as genes and mutations, is of significant importance to many research tasks in computational biology such as protein-protein interaction detection, gene-drug association…

Computation and Language · Computer Science 2020-07-01 Qingyu Chen , Kyubum Lee , Shankai Yan , Sun Kim , Chih-Hsuan Wei , Zhiyong Lu

Biomedical text mining is becoming increasingly important as the number of biomedical documents rapidly grows. With the progress in natural language processing (NLP), extracting valuable information from biomedical literature has gained…

Computation and Language · Computer Science 2019-10-21 Jinhyuk Lee , Wonjin Yoon , Sungdong Kim , Donghyeon Kim , Sunkyu Kim , Chan Ho So , Jaewoo Kang

Biomedical association studies are increasingly done using clinical concepts, and in particular diagnostic codes from clinical data repositories as phenotypes. Clinical concepts can be represented in a meaningful, vector space using word…

Quantitative Methods · Quantitative Biology 2018-11-06 Brett K. Beaulieu-Jones , Isaac S. Kohane , Andrew L. Beam

Concept bottleneck models (CBMs), which predict human-interpretable concepts (e.g., nucleus shapes in cell images) before predicting the final output (e.g., cell type), provide insights into the decision-making processes of the model.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Winnie Pang , Xueyi Ke , Satoshi Tsutsui , Bihan Wen

Knowledge graphs (KGs) are an important tool for representing complex relationships between entities in the biomedical domain. Several methods have been proposed for learning embeddings that can be used to predict new links in such graphs.…

Artificial Intelligence · Computer Science 2026-05-12 Daniel Daza , Dimitrios Alivanistos , Payal Mitra , Thom Pijnenburg , Michael Cochez , Paul Groth

This thesis work falls within the framework of question answering (QA) in the biomedical domain where several specific challenges are addressed, such as specialized lexicons and terminologies, the types of treated questions, and the…

Computation and Language · Computer Science 2023-07-26 Mourad Sarrouti

Biomedical text mining and question-answering are essential yet highly demanding tasks, particularly in the face of the exponential growth of biomedical literature. In this work, we present our participation in the 13th edition of the…

Computation and Language · Computer Science 2025-08-05 Dimitra Panou , Alexandros C. Dimopoulos , Manolis Koubarakis , Martin Reczko

Segmentation is a crucial analysis task in biomedical imaging. Given the diverse experimental settings in this field, the lack of generalization limits the use of deep learning in practice. Domain adaptation is a promising remedy: it…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Anwai Archit , Constantin Pape

We explore how continued pre-training on domain-specific corpora influences large language models, revealing that training on the raw corpora endows the model with domain knowledge, but drastically hurts its prompting ability for question…

Computation and Language · Computer Science 2024-07-26 Daixuan Cheng , Shaohan Huang , Furu Wei

``Classical'' word embeddings, such as Word2Vec, have been shown to capture the semantics of words based on their distributional properties. However, their ability to represent the different meanings that a word may have is limited. Such…

Computation and Language · Computer Science 2020-04-20 Lea Dieudonat , Kelvin Han , Phyllicia Leavitt , Esteban Marquer

Embedding models, which learn latent representations of users and items based on user-item interaction patterns, are a key component of recommendation systems. In many applications, contextual constraints need to be applied to refine…

Information Retrieval · Computer Science 2019-07-04 Syrine Krichene , Mike Gartrell , Clement Calauzenes

Applying machine learning algorithms to large-scale, text-based corpora (embeddings) presents a unique opportunity to investigate at scale how human semantic knowledge is organized and how people use it to judge fundamental relationships,…

Computation and Language · Computer Science 2020-07-17 Marius Cătălin Iordan , Tyler Giallanza , Cameron T. Ellis , Nicole M. Beckage , Jonathan D. Cohen

Topic models extract groups of words from documents, whose interpretation as a topic hopefully allows for a better understanding of the data. However, the resulting word groups are often not coherent, making them harder to interpret.…

Computation and Language · Computer Science 2021-06-18 Federico Bianchi , Silvia Terragni , Dirk Hovy

Recently, knowledge-grounded conversations in the open domain gain great attention from researchers. Existing works on retrieval-based dialogue systems have paid tremendous efforts to utilize neural networks to build a matching model, where…

Computation and Language · Computer Science 2025-09-30 Kai Hua , Zhiyuan Feng , Chongyang Tao , Rui Yan , Lu Zhang

Crosslingual word embeddings represent lexical items from different languages in the same vector space, enabling transfer of NLP tools. However, previous attempts had expensive resource requirements, difficulty incorporating monolingual…

Computation and Language · Computer Science 2016-07-01 Long Duong , Hiroshi Kanayama , Tengfei Ma , Steven Bird , Trevor Cohn

Tying the weights of the target word embeddings with the target word classifiers of neural machine translation models leads to faster training and often to better translation quality. Given the success of this parameter sharing, we…

Computation and Language · Computer Science 2018-09-03 Nikolaos Pappas , Lesly Miculicich Werlen , James Henderson

To enhance the domain-specific capabilities of large language models, continued pre-training on a domain-specific corpus is a prevalent method. Recent work demonstrates that adapting models using reading comprehension data formatted by…

Computation and Language · Computer Science 2024-01-19 Ting Jiang , Shaohan Huang , Shengyue Luo , Zihan Zhang , Haizhen Huang , Furu Wei , Weiwei Deng , Feng Sun , Qi Zhang , Deqing Wang , Fuzhen Zhuang

Large language models (LLMs) are increasingly recognized as valuable tools across the medical environment, supporting clinical, research, and administrative workflows. However, strict privacy and network security regulations in hospital…

Computation and Language · Computer Science 2026-01-09 Seokhwan Ko , Donghyeon Lee , Jaewoo Chun , Hyungsoo Han , Junghwan Cho

One of the cardinal tasks in achieving robust medical question answering systems is textual entailment. The existing approaches make use of an ensemble of pre-trained language models or data augmentation, often to clock higher numbers on…

Computation and Language · Computer Science 2020-11-11 Shweta Yadav , Vishal Pallagani , Amit Sheth

Biomedical concept normalization links concept mentions in texts to a semantically equivalent concept in a biomedical knowledge base. This task is challenging as concepts can have different expressions in natural languages, e.g.…

Computation and Language · Computer Science 2018-07-10 Roland Roller , Madeleine Kittner , Dirk Weissenborn , Ulf Leser
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