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Enhanced stabilisation of protein structures via the presence of inert excipients is a key mechanism adopted both by physiological systems and in biotechnological applications. While the intrinsic stability of proteins is ultimately fixed…

Biomolecules · Quantitative Biology 2023-05-10 Mattia Miotto , Nina Warner , Giancarlo Ruocco , Gian Gaetano Tartaglia , Oren A. Scherman , Edoardo Milanetti

Active-particle suspensions exhibit distinct polarization-density patterns in activity landscapes, even without anisotropic particle interactions. Such polarization without alignment forces is at work in motility-induced phase separation…

Soft Condensed Matter · Physics 2021-06-09 Nicola Andreas Söker , Sven Auschra , Viktor Holubec , Klaus Kroy , Frank Cichos

Active droplets are artificial microswimmers built from a liquid dispersion by microfluidic tools and showing self-propelled motion. These systems hold particular interest for mimicking biological phenomena, such as some aspects of cell…

Soft Condensed Matter · Physics 2023-06-14 Adriano Tiribocchi , Mihir Durve , Marco Lauricella , Andrea Montessori , Davide Marenduzzo , Sauro Succi

We numerically investigate how spatial variations of extensile or contractile active stress affect bulk active nematic systems in two and three dimensions. In the absence of defects, activity gradients drive flows which re-orient the…

Soft Condensed Matter · Physics 2022-06-15 Liam J Ruske , Julia M Yeomans

Systems driven far from equilibrium may exhibit anomalous density fluctuations: active matter with orientational order display giant density fluctuations at large scale, while systems of interacting particles close to an absorbing phase…

Statistical Mechanics · Physics 2026-03-23 Sara Dal Cengio , Romain Mari , Eric Bertin

How do topological defects affect the degree of order in active matter? To answer this question we investigate an agent-based model of self-propelled particles, which accounts for polar alignment and short-ranged repulsive interactions. For…

Soft Condensed Matter · Physics 2014-04-30 Christoph A. Weber , Christopher Bock , Erwin Frey

Spatially localised defect structures emerge spontaneously in a hydrodynamic description of an active polar fluid comprising polar 'actin' filaments and 'myosin' motor proteins that (un)bind to filaments and exert active contractile…

Biological Physics · Physics 2017-02-22 Kabir Husain , Madan Rao

We probe the effects of particle shape on the global and local behavior of a two-dimensional granular pillar, acting as a proxy for a disordered solid, under uniaxial compression. This geometry allows for direct measurement of global…

Soft Condensed Matter · Physics 2018-01-12 Matt Harrington , Douglas J. Durian

Active processes in living systems generate nonequilibrium forces that deform embedded passive macromolecules. To understand how such dynamics influence polymer conformation, we study a flexible passive chain in an active nematic fluid.…

Soft Condensed Matter · Physics 2025-09-30 Zahra K. Valei , Davide Marenduzzo , Tyler N. Shendruk

The dynamics of a membrane coupled to an active fluid on top of a substrate is considered theoretically. It is assumed that the director field of the active fluid has rotational symmetry in the membrane plane. This situation is likely to be…

Soft Condensed Matter · Physics 2020-04-08 Chia-Chun Liang , Kento Yasuda , Shigeyuki Komura , Kuo-An Wu , Hsuan-Yi Chen

The increase of aqueous solubility of nonpolar compounds upon cooling and the cold denaturation of proteins are established experimental facts. Both phenomena have been hypothesized to be related to restructuring of the hydrogen bond…

Soft Condensed Matter · Physics 2007-05-23 Sergey V. Buldyrev , Pradeep Kumar , H. Eugene Stanley

Active matter often simultaneously exhibits different kinds of orientational order and, in many cases of biological interest, undergoes continuous material renewal. In renewing nematopolar fluids we find stable topological strings,…

Soft Condensed Matter · Physics 2026-01-27 Alberto Dinelli , Ludovic Dumoulin , Karsten Kruse

Continuous and Boolean models for the Drosophila segment polarity network have shown that the system is able to maintain the wild-type pattern when subjected to sustained changes in the interaction parameters and initial conditions. Embryo…

Cell Behavior · Quantitative Biology 2009-06-19 Kartik Subramanian , Chetan Gadgil

Recent experiments suggest that the interplay between cells and the mechanics of their substrate gives rise to a diversity of morphological and migrational behaviors. Here, we develop a Cellular Potts Model of polarizing cells on a…

The dynamics of a passive scalar gradient experiencing fluctuating velocity gradient through the Lagrangian variations of strain persistence is studied. To this end, a systematic, numerical analysis based on the equation for the orientation…

Classical Physics · Physics 2017-02-02 A Garcia , M Gonzalez , P Paranthoën

The interplay between active matter and its environment is central to understanding emergent behavior in biological and synthetic systems. Here, we show that coupling active nematic flows to small-amplitude deformations of a compliant…

Soft Condensed Matter · Physics 2026-01-19 Varun Venkatesh , Amin Doostmohammadi

The control of the spin degree of freedom is at the heart of spintronics, which can potentially be achieved by spin-orbit coupling or band topological effects. In this paper, we explore another potential controlled mechanism under debate:…

Other Condensed Matter · Physics 2024-11-12 J. A. Sánchez-Monroy , Carlos Mera Acosta

One of the many ways cells transmit information within their volume is through steady spatial gradients of different proteins. However, the mechanism through which proteins without any sources or sinks form such single-cell gradients is not…

Biological Physics · Physics 2018-06-08 Saroj Kumar Nandi , Sam A. Safran

Suspensions of actively driven anisotropic objects exhibit distinctively nonequilibrium behaviors, and current theories predict that they are incapable of sustaining orientational order at high activity. By contrast, here we show that…

We demonstrate that two-dimensional crystals made of active particles can experience extremely large spontaneous deformations without melting. Using particles mostly interacting via pairwise repulsive forces, we show that such active…

Soft Condensed Matter · Physics 2023-09-11 Xia-qing Shi , Fu Cheng , Hugues Chaté