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Multiple instance learning (MIL) has become a preferred method for gigapixel whole slide image (WSI) classification without requiring patch-level annotations. Current MIL research primarily relies on embedding-based approaches, which…

Computer Vision and Pattern Recognition · Computer Science 2025-03-10 Bryan Wong , Sungrae Hong , Mun Yong Yi

Weakly supervised machine learning algorithms are able to learn from ambiguous samples or labels, e.g., multi-instance learning or partial-label learning. However, in some real-world tasks, each training sample is associated with not only…

Machine Learning · Computer Science 2022-12-20 Wei Tang , Weijia Zhang , Min-Ling Zhang

Multiple instance learning (MIL) can reduce the need for costly annotation in tasks such as semantic segmentation by weakening the required degree of supervision. We propose a novel MIL formulation of multi-class semantic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2015-04-16 Deepak Pathak , Evan Shelhamer , Jonathan Long , Trevor Darrell

Various multi-instance learning (MIL) based approaches have been developed and successfully applied to whole-slide pathological images (WSI). Existing MIL methods emphasize the importance of feature aggregators, but largely neglect the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Yicheng Song , Tiancheng Lin , Die Peng , Su Yang , Yi Xu

Multi-label Learning on Image data has been widely exploited with deep learning models. However, supervised training on deep CNN models often cannot discover sufficient discriminative features for classification. As a result, numerous…

Computer Vision and Pattern Recognition · Computer Science 2022-07-14 Xu Kaixin , Liu Liyang , Zhao Ziyuan , Zeng Zeng , Bharadwaj Veeravalli

Pathological image analysis is an important process for detecting abnormalities such as cancer from cell images. However, since the image size is generally very large, the cost of providing detailed annotations is high, which makes it…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Akihiko Yoshizawa , Tetsuo Ushiku , Masashi Fukayama , Masanobu Kitagawa , Masaru Kitsuregawa , Tatsuya Harada

Whole slide imaging is fundamental to biomedical microscopy and computational pathology. Previously, learning representations for gigapixel-sized whole slide images (WSIs) has relied on multiple instance learning with weak labels, which do…

Computer Vision and Pattern Recognition · Computer Science 2024-05-27 Xinhai Hou , Cheng Jiang , Akhil Kondepudi , Yiwei Lyu , Asadur Chowdury , Honglak Lee , Todd C. Hollon

Whole slide image (WSI) assessment is a challenging and crucial step in cancer diagnosis and treatment planning. WSIs require high magnifications to facilitate sub-cellular analysis. Precise annotations for patch- or even pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Simon Holdenried-Krafft , Peter Somers , Ivonne A. Montes-Majarro , Diana Silimon , Cristina Tarín , Falko Fend , Hendrik P. A. Lensch

In this paper, we introduce a novel learning scheme named weakly semi-supervised instance segmentation (WSSIS) with point labels for budget-efficient and high-performance instance segmentation. Namely, we consider a dataset setting…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Beomyoung Kim , Joonhyun Jeong , Dongyoon Han , Sung Ju Hwang

Weakly supervised instance labeling using only image-level labels, in lieu of expensive fine-grained pixel annotations, is crucial in several applications including medical image analysis. In contrast to conventional instance segmentation…

Computer Vision and Pattern Recognition · Computer Science 2019-07-31 Jayaraman J. Thiagarajan , Satyananda Kashyap , Alexandros Karagyris

Biomarker detection is an indispensable part of the diagnosis and treatment of low-grade glioma (LGG). However, current LGG biomarker detection methods rely on expensive and complex molecular genetic testing, for which professionals are…

Image and Video Processing · Electrical Eng. & Systems 2026-04-21 Zijie Fang , Yihan Liu , Yifeng Wang , Xiangyang Zhang , Yang Chen , Changjing Cai , Yiyang Lin , Ying Han , Zhi Wang , Shan Zeng , Jun Tan , Yongbing Zhang , Hong Shen

Weakly-supervised instance segmentation (WSIS) has been considered as a more challenging task than weakly-supervised semantic segmentation (WSSS). Compared to WSSS, WSIS requires instance-wise localization, which is difficult to extract…

Computer Vision and Pattern Recognition · Computer Science 2022-03-30 Beomyoung Kim , Youngjoon Yoo , Chaeeun Rhee , Junmo Kim

\textit{Multiple Instance Learning} (MIL) is concerned with learning from bags of instances, where only bag labels are given and instance labels are unknown. Existent approaches in this field were mainly designed for the bag-level label…

Machine Learning · Computer Science 2019-05-30 Minlong Peng , Qi Zhang

Multiple instance learning (MIL) has been successfully applied for whole slide images (WSIs) analysis in computational pathology, enabling a wide range of prediction tasks from tumor subtyping to inferring genetic mutations and multi-omics…

Computer Vision and Pattern Recognition · Computer Science 2024-07-25 Junyu Li , Ye Zhang , Wen Shu , Xiaobing Feng , Yingchun Wang , Pengju Yan , Xiaolin Li , Chulin Sha , Min He

We study a multiclass multiple instance learning (MIL) problem where the labels only suggest whether any instance of a class exists or does not exist in a training sample or example. No further information, e.g., the number of instances of…

Machine Learning · Statistics 2019-03-15 Xi-Lin Li

The Multiple Instance Hybrid Estimator for discriminative target characterization from imprecisely labeled hyperspectral data is presented. In many hyperspectral target detection problems, acquiring accurately labeled training data is…

Computer Vision and Pattern Recognition · Computer Science 2019-03-20 Changzhe Jiao , Chao Chen , Ronald G. McGarvey , Stephanie Bohlman , Licheng Jiao , Alina Zare

Multiple Instance Learning (MIL) is widely used in analyzing histopathological Whole Slide Images (WSIs). However, existing MIL methods do not explicitly model the data distribution, and instead they only learn a bag-level or instance-level…

Computer Vision and Pattern Recognition · Computer Science 2022-06-20 Linhao Qu , Xiaoyuan Luo , Shaolei Liu , Manning Wang , Zhijian Song

Whole-slide images (WSIs) are critical for cancer diagnosis due to their ultra-high resolution and rich semantic content. However, their massive size and the limited availability of fine-grained annotations pose substantial challenges for…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Daoxi Cao , Hangbei Cheng , Yijin Li , Ruolin Zhou , Xuehan Zhang , Xinyi Li , Binwei Li , Xuancheng Gu , Jianan Zhang , Xueyu Liu , Yongfei Wu

As we all know, multi-view data is more expressive than single-view data and multi-label annotation enjoys richer supervision information than single-label, which makes multi-view multi-label learning widely applicable for various pattern…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Chengliang Liu , Jie Wen , Xiaoling Luo , Yong Xu

Multiple Instance Learning (MIL) has been widely used in weakly supervised whole slide image (WSI) classification. Typical MIL methods include a feature embedding part, which embeds the instances into features via a pre-trained feature…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Peijie Qiu , Pan Xiao , Wenhui Zhu , Yalin Wang , Aristeidis Sotiras
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