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Modeling & Simulation (M&S) approaches such as agent-based models hold significant potential to support decision-making activities in health, with recent examples including the adoption of vaccines, and a vast literature on healthy eating…

Artificial Intelligence · Computer Science 2025-09-08 Philippe J. Giabbanelli , Ameeta Agrawal

Efficient sampling in biomolecular simulations is critical for accurately capturing the complex dynamical behaviors of biological systems. Adaptive sampling techniques aim to improve efficiency by focusing computational resources on the…

Biomolecules · Quantitative Biology 2024-10-22 Hassan Nadeem , Diwakar Shukla

Conversational Recommender Systems (CRSs) have garnered attention as a novel approach to delivering personalized recommendations through multi-turn dialogues. This review developed a taxonomy framework to systematically categorize relevant…

Human-Computer Interaction · Computer Science 2025-06-26 Haoran Zhang , Xin Zhao , Jinze Chen , Junpeng Guo

Precision medicine is currently a topic of great interest in clinical and intervention science. One way to formalize precision medicine is through a treatment regime, which is a sequence of decision rules, one per stage of clinical…

Methodology · Statistics 2016-06-07 Yichi Zhang , Eric B. Laber , Anastasios Tsiatis , Marie Davidian

Optimal treatment regimes are personalized policies for making a treatment decision based on subject characteristics, with the policy chosen to maximize some value. It is common to aim to maximize the mean outcome in the population, via a…

Methodology · Statistics 2022-02-28 Liu Leqi , Edward H. Kennedy

Nowadays, the quality of responses generated by different modern large language models (LLMs) is hard to evaluate and compare automatically. Recent studies suggest and predominantly use LLMs for reference-free evaluation of open-ended…

Computation and Language · Computer Science 2025-01-03 Ruosen Li , Teerth Patel , Xinya Du

Ranking models have achieved promising results, but it remains challenging to design personalized ranking systems to leverage user profiles and semantic representations between queries and documents. In this paper, we propose a topic-based…

Information Retrieval · Computer Science 2021-08-16 Minghui Huang , Wei Peng , Dong Wang

We consider the problem of selecting the optimal subgroup to treat when data on covariates is available from a randomized trial or observational study. We distinguish between four different settings including (i) treatment selection when…

Methodology · Statistics 2018-02-28 Tyler J. VanderWeele , Alex R. Luedtke , Mark J. van der Laan , Ronald C. Kessler

We study the design of multi-armed parallel group clinical trials to estimate personalized treatment rules that identify the best treatment for a given patient with given covariates. Assuming that the outcomes in each treatment arm are…

Statistics Theory · Mathematics 2022-07-13 David Azriel , Yosef Rinott , Martin Posch

Estimating individualized treatment effects from longitudinal observational data is central to data-driven medicine, yet existing methods face a fundamental limitation: reducing confounding bias often suppresses clinically informative…

The real-world testing of decisions made using causal machine learning models is an essential prerequisite for their successful application. We focus on evaluating and improving contextual treatment assignment decisions: these are…

Machine Learning · Statistics 2022-07-13 Desi R. Ivanova , Joel Jennings , Cheng Zhang , Adam Foster

Causal classification models are adopted across a variety of operational business processes to predict the effect of a treatment on a categorical business outcome of interest depending on the process instance characteristics. This allows…

Machine Learning · Computer Science 2021-01-06 Diego Olaya , Wouter Verbeke , Jente Van Belle , Marie-Anne Guerry

In many mobile health interventions, treatments should only be delivered in a particular context, for example when a user is currently stressed, walking or sedentary. Even in an optimal context, concerns about user burden can restrict which…

Machine Learning · Computer Science 2018-12-04 Sabina Tomkins , Predrag Klasnja , Susan Murphy

Dynamic treatment regimes operationalize the clinical decision process as a sequence of functions, one for each clinical decision, where each function takes as input up-to-date patient information and gives as output a single recommended…

Methodology · Statistics 2012-08-08 Eric B. Laber , Daniel J. Lizotte , Bradley Ferguson

Personalized alignment from preference data has focused primarily on improving personal reward model (RM) accuracy, with the implicit assumption that better preference ranking translates to better personalized behavior. However, in…

Artificial Intelligence · Computer Science 2026-01-09 Fady Rezk , Yuangang Pan , Chuan-Sheng Foo , Xun Xu , Nancy Chen , Henry Gouk , Timothy Hospedales

Recent statistical and reinforcement learning methods have significantly advanced patient care strategies. However, these approaches face substantial challenges in high-stakes contexts, including missing data, inherent stochasticity, and…

Machine Learning · Computer Science 2024-04-02 Harsh Parikh , Quinn Lanners , Zade Akras , Sahar F. Zafar , M. Brandon Westover , Cynthia Rudin , Alexander Volfovsky

Large language models (LLMs) have significant potential to improve operational efficiency in operations management. Deploying these models requires specifying a policy that governs response quality, shapes user experience, and influences…

Machine Learning · Computer Science 2026-04-13 Mingjie Hu , Siyang Gao , Jian-qiang Hu , Enlu Zhou

Users are able to access millions of songs through music streaming services like Spotify, Pandora, and Deezer. Access to such large catalogs, created a need for relevant song recommendations. However, user preferences are highly subjective…

Information Retrieval · Computer Science 2020-09-08 Boning Gong , Mesut Kaya , Nava Tintarev

Recent shifts in global health priorities have positioned Population Health Management (PHM) as a central area of focus. However, optimizing PHM strategies presents several challenges: managing high-dimensional patient covariates, tracking…

Optimization and Control · Mathematics 2026-04-10 Daniel Adelman , Alba V Olivares-Nadal , Miaolan Xie

Existing neural relevance models do not give enough consideration for query and item context information which diversifies the search results to adapt for personal preference. To bridge this gap, this paper presents a neural learning…

Information Retrieval · Computer Science 2023-09-12 Deguang Kong , Daniel Zhou , Zhiheng Huang , Steph Sigalas