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Convolutional neural networks can be trained to perform histology slide classification using weak annotations with multiple instance learning (MIL). However, given the paucity of labeled histology data, direct application of MIL can easily…

Computer Vision and Pattern Recognition · Computer Science 2019-11-05 Ming Y. Lu , Richard J. Chen , Jingwen Wang , Debora Dillon , Faisal Mahmood

Deep co-training has recently been proposed as an effective approach for image segmentation when annotated data is scarce. In this paper, we improve existing approaches for semi-supervised segmentation with a self-paced and self-consistent…

Computer Vision and Pattern Recognition · Computer Science 2021-07-15 Ping Wang , Jizong Peng , Marco Pedersoli , Yuanfeng Zhou , Caiming Zhang , Christian Desrosiers

Learning discriminative image representations plays a vital role in long-tailed image classification because it can ease the classifier learning in imbalanced cases. Given the promising performance contrastive learning has shown recently in…

Computer Vision and Pattern Recognition · Computer Science 2021-03-29 Peng Wang , Kai Han , Xiu-Shen Wei , Lei Zhang , Lei Wang

Accurate gland segmentation in histopathology images is essential for cancer diagnosis and prognosis. However, significant variability in Hematoxylin and Eosin (H&E) staining and tissue morphology, combined with limited annotated data,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Ha-Hieu Pham , Nguyen Lan Vi Vu , Thanh-Huy Nguyen , Ulas Bagci , Min Xu , Trung-Nghia Le , Huy-Hieu Pham

Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and Intra-observer…

Computer Vision and Pattern Recognition · Computer Science 2021-11-03 Chetan L. Srinidhi , Seung Wook Kim , Fu-Der Chen , Anne L. Martel

Disease diagnosis from medical images via supervised learning is usually dependent on tedious, error-prone, and costly image labeling by medical experts. Alternatively, semi-supervised learning and self-supervised learning offer…

Computer Vision and Pattern Recognition · Computer Science 2023-06-14 Attiano Purpura-Pontoniere , Demetri Terzopoulos , Adam Wang , Abdullah-Al-Zubaer Imran

An important part of Digital Pathology is the analysis of multiple digitised whole slide images from differently stained tissue sections. It is common practice to mount consecutive sections containing corresponding microscopic structures on…

Computer Vision and Pattern Recognition · Computer Science 2018-11-06 Thomas Lampert , Odyssée Merveille , Jessica Schmitz , Germain Forestier , Friedrich Feuerhake , Cédric Wemmert

Most existing graph-based semi-supervised hyperspectral image classification methods rely on superpixel partitioning techniques. However, they suffer from misclassification of certain pixels due to inaccuracies in superpixel boundaries,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Yuqing Zhang , Qi Han , Ligeng Wang , Kai Cheng , Bo Wang , Kun Zhan

Convolutional Neural Networks (CNNs) have achieved state-of-the-art performance for medical image segmentation, yet need plenty of manual annotations for training. Semi-Supervised Learning (SSL) methods are promising to reduce the…

Computer Vision and Pattern Recognition · Computer Science 2022-08-19 Ran Gu , Jingyang Zhang , Guotai Wang , Wenhui Lei , Tao Song , Xiaofan Zhang , Kang Li , Shaoting Zhang

A key requirement for the success of supervised deep learning is a large labeled dataset - a condition that is difficult to meet in medical image analysis. Self-supervised learning (SSL) can help in this regard by providing a strategy to…

Computer Vision and Pattern Recognition · Computer Science 2020-11-02 Krishna Chaitanya , Ertunc Erdil , Neerav Karani , Ender Konukoglu

In many critical computer vision scenarios unlabeled data is plentiful, but labels are scarce and difficult to obtain. As a result, semi-supervised learning which leverages unlabeled data to boost the performance of supervised classifiers…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Jay C. Rothenberger , Dimitrios I. Diochnos

This paper presents a new regularization method to train a fully convolutional network for semantic tissue segmentation in histopathological images. This method relies on the benefit of unsupervised learning, in the form of image…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 C. T. Sari , C. Sokmensuer , C. Gunduz-Demir

Semantic segmentation of various tissue and nuclei types in histology images is fundamental to many downstream tasks in the area of computational pathology (CPath). In recent years, Deep Learning (DL) methods have been shown to perform well…

Computer Vision and Pattern Recognition · Computer Science 2023-02-14 Raja Muhammad Saad Bashir , Talha Qaiser , Shan E Ahmed Raza , Nasir M. Rajpoot

We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…

The objective of this paper is visual-only self-supervised video representation learning. We make the following contributions: (i) we investigate the benefit of adding semantic-class positives to instance-based Info Noise Contrastive…

Computer Vision and Pattern Recognition · Computer Science 2021-01-13 Tengda Han , Weidi Xie , Andrew Zisserman

We propose a Deep learning-based weak label learning method for analyzing whole slide images (WSIs) of Hematoxylin and Eosin (H&E) stained tumor tissue not requiring pixel-level or tile-level annotations using Self-supervised pre-training…

Image and Video Processing · Electrical Eng. & Systems 2023-06-29 Yoni Schirris , Efstratios Gavves , Iris Nederlof , Hugo Mark Horlings , Jonas Teuwen

Multiple instance (MI) learning with a convolutional neural network enables end-to-end training in the presence of weak image-level labels. We propose a new method for aggregating predictions from smaller regions of the image into an…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Heather D. Couture , J. S. Marron , Charles M. Perou , Melissa A. Troester , Marc Niethammer

Heterogeneous graph neural networks (HGNNs) as an emerging technique have shown superior capacity of dealing with heterogeneous information network (HIN). However, most HGNNs follow a semi-supervised learning manner, which notably limits…

Machine Learning · Computer Science 2024-03-06 Nian Liu , Xiao Wang , Hui Han , Chuan Shi

Universal, transferable whole-slide image (WSI) representations are central to computational pathology. Incorporating multiple markers (e.g., immunohistochemistry, IHC) alongside H&E enriches H&E-based features with diverse, biologically…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Yizhi Zhang , Lei Fan , Zhulin Tao , Donglin Di , Yang Song , Sidong Liu , Cong Cong

For medical image segmentation, contrastive learning is the dominant practice to improve the quality of visual representations by contrasting semantically similar and dissimilar pairs of samples. This is enabled by the observation that…

Computer Vision and Pattern Recognition · Computer Science 2023-10-25 Chenyu You , Weicheng Dai , Yifei Min , Fenglin Liu , David A. Clifton , S Kevin Zhou , Lawrence Hamilton Staib , James S Duncan