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In vitro models play a crucial role in advancing our understanding of biological processes, disease mechanisms, and developing screening platforms for drug discovery. Kidneys play an instrumental role in transport and elimination of drugs…

Tissues and Organs · Quantitative Biology 2025-02-20 Charlotte A Veser , Aurélie MF Carlier , Silvia M Mihăilă , Sangita Swapnasrita

Kidney transplantation can significantly enhance living standards for people suffering from end-stage renal disease. A significant factor that affects graft survival time (the time until the transplant fails and the patient requires another…

Machine Learning · Computer Science 2022-07-07 Mohammadreza Nemati , Haonan Zhang , Michael Sloma , Dulat Bekbolsynov , Hong Wang , Stanislaw Stepkowski , Kevin S. Xu

Background: Chronic kidney disease (CKD), a progressive disease with high morbidity and mortality, has become a significant global public health problem. Most existing models are static and fail to capture temporal trends in disease…

Machine Learning · Computer Science 2025-10-03 Jingying Ma , Jinwei Wang , Lanlan Lu , Yexiang Sun , Mengling Feng , Feifei Zhang , Peng Shen , Zhiqin Jiang , Shenda Hong , Luxia Zhang

Kidney stone disease ranks among the most prevalent conditions in urology, and understanding the composition of these stones is essential for creating personalized treatment plans and preventing recurrence. Current methods for analyzing…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Changmiao Wang , Songqi Zhang , Yongquan Zhang , Yifei Wang , Liya Liu , Nannan Li , Xingzhi Li , Jiexin Pan , Yi Jiang , Xiang Wan , Hai Wang , Ahmed Elazab

Knowledge graph embedding~(KGE) aims to represent entities and relations into low-dimensional vectors for many real-world applications. The representations of entities and relations are learned via contrasting the positive and negative…

Artificial Intelligence · Computer Science 2022-02-22 Feihu Che , Guohua Yang , Pengpeng Shao , Dawei Zhang , Jianhua Tao

Payment channel networks (PCNs) are a promising approach to making cryptocurrency transactions faster and more scalable. At their core, PCNs bypass the blockchain by routing transactions through intermediary channels. However, a channel can…

Data Structures and Algorithms · Computer Science 2026-05-19 Marcin Bienkowski , Julien Dallot , Dominik Danelski , Maciej Pacut , Stefan Schmid

Joint replacement is the most common inpatient surgical treatment in the US. We investigate the clinical pathway optimization for knee replacement, which is a sequential decision process from onset to recovery. Based on episodic claims from…

Machine Learning · Computer Science 2019-06-05 Hao Lu , Mengdi Wang

This paper focuses on two-sided matching where one side (a hospital or firm) is matched to the other side (a doctor or worker) so as to maximize a cardinal objective under general feasibility constraints. In a standard model, even though…

Computer Science and Game Theory · Computer Science 2019-07-10 Yasushi Kawase , Atsushi Iwasaki

In this paper, we investigate relay selection for cooperative multiple-antenna systems that are equipped with buffers, which increase the reliability of wireless links. In particular, we present a novel relay selection technique based on…

Information Theory · Computer Science 2019-03-27 F. L. Duarte , R. C. de Lamare

We study two-sided matching markets under hereditary constraints, which extend beyond simple capacity limits and arise in applications such as diversity requirements and refugee resettlement. In these settings, fairness and non-wastefulness…

Computer Science and Game Theory · Computer Science 2026-05-04 Tenma Wakasugi , Zhaohong Sun , Kei Kimura , Makoto Yokoo

This paper considers a multiple input multiple output (MIMO) two-way relay channel, where two nodes want to exchange data with each other using multiple relays. An iterative algorithm is proposed to achieve the optimal achievable rate…

Information Theory · Computer Science 2008-10-22 Rahul Vaze , Robert W. Heath

Extensive research has been done to achieve better throughput and reliability in wireless networks, with focus on multiple-input multiple-output systems. Recently, cooperative networking techniques have been investigated to increase the…

Networking and Internet Architecture · Computer Science 2019-11-19 Muhammad Asam , Zeeshan Haider , Tauseef Jamal , Kashif Ghuman , Aleena Ajaz

We consider variable selection in competing risks regression for multi-center data. Our research is motivated by deceased donor kidney transplants, from which recipients would experience graft failure, death with functioning graft (DWFG),…

Methodology · Statistics 2016-10-20 Zhixuan Fu , Shuangge Ma , Haiqun Lin , Chirag R Parikh , Bingqing Zhou

The time-varying effects model is a flexible and powerful tool for modeling the dynamic changes of covariate effects. However, in survival analysis, its computational burden increases quickly as the number of sample sizes or predictors…

Computation · Statistics 2020-01-01 Kevin He , Ji Zhu , Jian Kang , Yi Li

Artificial intelligence (AI) in healthcare has the potential to improve patient outcomes, but clinician acceptance remains a critical barrier. We developed a novel decision support interface that provides interpretable treatment…

Human-Computer Interaction · Computer Science 2023-02-02 Venkatesh Sivaraman , Leigh A. Bukowski , Joel Levin , Jeremy M. Kahn , Adam Perer

Incentivizing the existing participants to invite new participants to join an auction, matching or cooperative game have been extensively studied recently. One common challenge to design such incentive in these games is that the invitees…

Computer Science and Game Theory · Computer Science 2025-02-17 Xinwei Song , Tianyi Yang , Dengji Zhao

The allocation of scarce donor organs constitutes one of the most consequential algorithmic challenges in healthcare. While the field is rapidly transitioning from rigid, rule-based systems to machine learning and data-driven optimization,…

Machine Learning · Computer Science 2026-05-27 Ioannis Anagnostides , Itai Zilberstein , Zachary W. Sollie , Arman Kilic , Tuomas Sandholm

We consider the problem of selecting $k$ seed nodes in a network to maximize the minimum probability of activation under an independent cascade beginning at these seeds. The motivation is to promote fairness by ensuring that even the least…

Social and Information Networks · Computer Science 2025-02-20 Dennis Robert Windham , Caroline J. Wendt , Alex Crane , Madelyn J Warr , Freda Shi , Sorelle A. Friedler , Blair D. Sullivan , Aaron Clauset

The aim of this research is twofold: Firstly, to model and solve a complex nurse scheduling problem with an integer programming formulation and evolutionary algorithms. Secondly, to detail a novel statistical method of comparing and hence…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin , Paul White

Several mating restriction techniques have been implemented in Evolutionary Algorithms to promote diversity. From similarity-based selection to niche preservation, the general goal is to avoid premature convergence by not having fitness…

Neural and Evolutionary Computing · Computer Science 2025-04-09 José Maria Simões , Nuno Lourenço , Penousal Machado
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