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Accurate molecular property prediction requires integrating complementary information from molecular structure and chemical semantics. In this work, we propose LGM-CL, a local-global multimodal contrastive learning framework that jointly…

Machine Learning · Computer Science 2026-02-02 Xiayu Liu , Zhengyi Lu , Yunhong Liao , Chan Fan , Hou-biao Li

Protein-protein interaction (PPI) prediction is an instrumental means in elucidating the mechanisms underlying cellular operations, holding significant practical implications for the realms of pharmaceutical development and clinical…

Machine Learning · Computer Science 2025-03-07 Jiang Li , Xiaoping Wang

Transformers have profoundly influenced AI research, but explaining their decisions remains challenging -- even for relatively simpler tasks such as classification -- which hinders trust and safe deployment in real-world applications.…

Computation and Language · Computer Science 2025-07-30 Sungmin Han , Jeonghyun Lee , Sangkyun Lee

Multivariate Time Series (MTS) anomaly detection focuses on pinpointing samples that diverge from standard operational patterns, which is crucial for ensuring the safety and security of industrial applications. The primary challenge in this…

Machine Learning · Computer Science 2024-04-19 Haili Sun , Yan Huang , Lansheng Han , Cai Fu , Chunjie Zhou

Standard few-shot relation classification (RC) is designed to learn a robust classifier with only few labeled data for each class. However, previous works rarely investigate the effects of a different number of classes (i.e., $N$-way) and…

Machine Learning · Computer Science 2021-10-19 Hongru Wang , Zhijing Jin , Jiarun Cao , Gabriel Pui Cheong Fung , Kam-Fai Wong

Deep neural networks are vulnerable to adversarial noise. Adversarial Training (AT) has been demonstrated to be the most effective defense strategy to protect neural networks from being fooled. However, we find AT omits to learning robust…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Nuoyan Zhou , Nannan Wang , Decheng Liu , Dawei Zhou , Xinbo Gao

Automatic code review (ACR), aiming to relieve manual inspection costs, is an indispensable and essential task in software engineering. The existing works only use the source code fragments to predict the results, missing the exploitation…

Software Engineering · Computer Science 2022-05-31 Bingting Wu , Xiaofang Zhang

Contrastive learning has gained significant attention in short text clustering, yet it has an inherent drawback of mistakenly identifying samples from the same category as negatives and then separating them in the feature space (false…

Machine Learning · Computer Science 2026-03-16 Zhihao Yao

Contrastive learning, as a self-supervised learning paradigm, becomes popular for Multivariate Time-Series (MTS) classification. It ensures the consistency across different views of unlabeled samples and then learns effective…

Machine Learning · Computer Science 2024-01-11 Yucheng Wang , Yuecong Xu , Jianfei Yang , Min Wu , Xiaoli Li , Lihua Xie , Zhenghua Chen

Modern techniques like contrastive learning have been effectively used in many areas, including computer vision, natural language processing, and graph-structured data. Creating positive examples that assist the model in learning robust and…

Machine Learning · Computer Science 2024-02-19 Xu Zheng , Tianchun Wang , Wei Cheng , Aitian Ma , Haifeng Chen , Mo Sha , Dongsheng Luo

Identifying metabolic sites where cytochrome P450 enzymes metabolize small-molecule drugs is essential for drug discovery. Although existing computational approaches have been proposed for site-of-metabolism prediction, they typically…

Quantitative Methods · Quantitative Biology 2026-01-30 Hajung Kim , Eunha Lee , Sohyun Chung , Jueon Park , Seungheun Baek , Jaewoo Kang

Deploying continual object detection on microcontrollers (MCUs) with under 100KB memory requires efficient feature compression that can adapt to evolving task distributions. Existing approaches rely on fixed compression strategies (e.g.,…

Artificial Intelligence · Computer Science 2026-04-14 Bibin Wilson

Diverse repertoires of hypervariable immunoglobulin receptors (TCR and BCR) recognize antigens in the adaptive immune system. The development of immunoglobulin receptor repertoire sequencing methods makes it possible to perform…

Accurate segmentation of coronary Digital Subtraction Angiography images is essential to diagnose and treat coronary artery diseases. Despite advances in deep learning, challenges such as high intra-class variance and class imbalance limit…

Computer Vision and Pattern Recognition · Computer Science 2025-05-08 Rayan Merghani Ahmed , Adnan Iltaf , Mohamed Elmanna , Gang Zhao , Hongliang Li , Yue Du , Bin Li , Shoujun Zhou

Graph contrastive learning (GCL) aims to learn discriminative semantic invariance by contrasting different views of the same graph that share critical topological patterns. However, existing GCL approaches with structural augmentations…

Machine Learning · Computer Science 2025-12-03 Qirui Ji , Bin Qin , Yifan Jin , Yunze Zhao , Chuxiong Sun , Changwen Zheng , Jianwen Cao , Jiangmeng Li

Recognizing underwater targets from acoustic signals is a challenging task owing to the intricate ocean environments and variable underwater channels. While deep learning-based systems have become the mainstream approach for underwater…

Sound · Computer Science 2024-02-21 Yuan Xie , Jiawei Ren , Ji Xu

Detecting critical transitions in complex, noisy time-series data is a fundamental challenge across science and engineering. Such transitions may be anticipated by the emergence of a low-dimensional order parameter, whose signature is often…

Machine Learning · Computer Science 2025-12-16 Wenqi Fang , Ye Li

Improving the performance of click-through rate (CTR) prediction remains one of the core tasks in online advertising systems. With the rise of deep learning, CTR prediction models with deep networks remarkably enhance model capacities. In…

Machine Learning · Computer Science 2019-11-05 Yikai Wang , Liang Zhang , Quanyu Dai , Fuchun Sun , Bo Zhang , Yang He , Weipeng Yan , Yongjun Bao

Extracting expressive visual features is crucial for accurate Click-Through-Rate (CTR) prediction in visual search advertising systems. Current commercial systems use off-the-shelf visual encoders to facilitate fast online service. However,…

Information Retrieval · Computer Science 2022-05-10 Si Chen , Chen Lin , Wanxian Guan , Jiayi Wei , Xingyuan Bu , He Guo , Hui Li , Xubin Li , Jian Xu , Bo Zheng

In this work, we exploit the task of joint classification and weakly supervised localization of thoracic diseases from chest radiographs, with only image-level disease labels coupled with disease severity-level (DSL) information of a…

Computer Vision and Pattern Recognition · Computer Science 2018-07-20 Yuxing Tang , Xiaosong Wang , Adam P. Harrison , Le Lu , Jing Xiao , Ronald M. Summers