Related papers: Attention-aware contrastive learning for predictin…
Annotating automatic target recognition (ATR) is a highly challenging task, primarily due to the unavailability of labeled data in the target domain. Hence, it is essential to construct an optimal target domain classifier by utilizing the…
Designing full-length, epitope-specific TCR {\alpha}\b{eta} remains challenging due to vast sequence space, data biases and incomplete modeling of immunogenetic constraints. We present LSMTCR, a scalable multi-architecture framework that…
T lymphocytes (T cells) orchestrate adaptive immune responses upon activation. T cell activation requires sufficiently strong binding of T cell receptors (TCRs) on their surface to short peptides (p) derived from foreign proteins, which are…
Drug-target interaction (DTI) prediction is crucial for drug development and repositioning. Methods using heterogeneous graph neural networks (HGNNs) for DTI prediction have become a promising approach, with attention-based models often…
Early detection of cancers has been much explored due to its paramount importance in biomedical fields. Among different types of data used to answer this biological question, studies based on T cell receptors (TCRs) are under recent…
Hypervariable T-cell receptors (TCR) play a key role in adaptive immunity, recognising a vast diversity of pathogen-derived antigens. High throughput sequencing of TCR repertoires (RepSeq) produces huge datasets of T-cell receptor sequences…
We introduce the Temporal Contrastive Transformer (TCT), a representation learning framework designed to capture contextual temporal dynamics in sequences of financial transactions. The model is trained using a self-supervised contrastive…
In protein biophysics, the separation between the functionally important residues (forming the active site or binding surface) and those that create the overall structure (the fold) is a well-established and fundamental concept. Identifying…
This study introduces the Multi-Scale Weight-Based Pairwise Coarsening and Contrastive Learning (MPCCL) model, a novel approach for attributed graph clustering that effectively bridges critical gaps in existing methods, including long-range…
Motivated by the success of coarse-grained or fine-grained contrast in text-video retrieval, there emerge multi-grained contrastive learning methods which focus on the integration of contrasts with different granularity. However, due to the…
Hierarchical classification is a crucial task in many applications, where objects are organized into multiple levels of categories. However, conventional classification approaches often neglect inherent inter-class relationships at…
In medical time series disease diagnosis, two key challenges are identified. First, the high annotation cost of medical data leads to overfitting in models trained on label-limited, single-center datasets. To address this, we propose…
Drug-target binding affinity prediction plays an important role in the early stages of drug discovery, which can infer the strength of interactions between new drugs and new targets. However, the performance of previous computational models…
Reliable detection of anomalies is crucial when deploying machine learning models in practice, but remains challenging due to the lack of labeled data. To tackle this challenge, contrastive learning approaches are becoming increasingly…
Vision Transformer (ViT) has shown its advantages over the convolutional neural network (CNN) with its ability to capture global long-range dependencies for visual representation learning. Besides ViT, contrastive learning is another…
Contrastive learning has moved the state of the art for many tasks in computer vision and information retrieval in recent years. This poster is the first work that applies supervised contrastive learning to the task of product matching in…
Alongside neuroimaging such as MRI scans and PET, Alzheimer's disease (AD) datasets contain valuable tabular data including AD biomarkers and clinical assessments. Existing computer vision approaches struggle to utilize this additional…
Knowledge tracing (KT) refers to the problem of predicting future learner performance given their past performance in educational applications. Recent developments in KT using flexible deep neural network-based models excel at this task.…
In recent years, self-supervised representation learning for skeleton-based action recognition has been developed with the advance of contrastive learning methods. The existing contrastive learning methods use normal augmentations to…
Contrastive representation learning is crucial in time series analysis as it alleviates the issue of data noise and incompleteness as well as sparsity of supervision signal. However, existing constrastive learning frameworks usually focus…