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Pathology plays an important role in disease diagnosis, treatment decision-making and drug development. Previous works on interpretability for machine learning models on pathology images have revolved around methods such as attention value…

The claims data, containing medical codes, services information, and incurred expenditure, can be a good resource for estimating an individual's health condition and medical risk level. In this study, we developed Transformer-based…

Machine Learning · Computer Science 2021-06-25 Xianlong Zeng , Simon Lin , Chang Liu

Survival analysis has been developed and applied in the number of areas including manufacturing, finance, economics and healthcare. In healthcare domain, usually clinical data are high-dimensional, sparse and complex and sometimes there…

Machine Learning · Computer Science 2018-08-13 Milad Zafar Nezhad , Najibesadat Sadati , Kai Yang , Dongxiao Zhu

Cancer survival prediction from multi-omics data remains challenging because prognostic signals are high-dimensional, heterogeneous, and distributed across interacting genes and pathways. We propose PathMoG, a pathway-centric modular graph…

Machine Learning · Computer Science 2026-04-28 Di Wang , Chupei Tang , Junxiao Kong , Jixiu Zhai , Moyu Tang , Tianchi Lu

Accurate cancer survival prediction requires integration of diverse data modalities that reflect the complex interplay between imaging, clinical parameters, and textual reports. However, existing multimodal approaches suffer from simplistic…

Machine Learning · Computer Science 2025-07-01 Aakash Tripathi , Asim Waqas , Matthew B. Schabath , Yasin Yilmaz , Ghulam Rasool

There has been a growing interest in using deep learning models for processing long surgical videos, in order to automatically detect clinical/operational activities and extract metrics that can enable workflow efficiency tools and…

Computer Vision and Pattern Recognition · Computer Science 2023-05-22 Muhammad Abdullah Jamal , Omid Mohareri

Deep neural networks are powerful tools for biomedical image segmentation. These models are often trained with heavy supervision, relying on pairs of images and corresponding voxel-level labels. However, obtaining segmentations of…

Image and Video Processing · Electrical Eng. & Systems 2020-04-30 Evan M. Yu , Juan Eugenio Iglesias , Adrian V. Dalca , Mert R. Sabuncu

Recent advances in high-throughput sequencing technologies have enabled the extraction of multiple features that depict patient samples at diverse and complementary molecular levels. The generation of such data has led to new challenges in…

Genomics · Quantitative Biology 2022-09-14 Hakim Benkirane , Yoann Pradat , Stefan Michiels , Paul-Henry Cournède

Unsupervised learning can leverage large-scale data sources without the need for annotations. In this context, deep learning-based autoencoders have shown great potential in detecting anomalies in medical images. However, especially…

Image and Video Processing · Electrical Eng. & Systems 2020-01-03 David Zimmerer , Simon Kohl , Jens Petersen , Fabian Isensee , Klaus Maier-Hein

Cancer remains one of the leading causes of mortality worldwide, necessitating accurate diagnosis and prognosis. Whole Slide Imaging (WSI) has become an integral part of clinical workflows with advancements in digital pathology. While…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Ahmad Hussein , Mukesh Prasad , Ali Anaissi , Ali Braytee

Research in the past years introduced Steered Mixture-of-Experts (SMoE) as a framework to form sparse, edge-aware models for 2D- and higher dimensional pixel data, applicable to compression, denoising, and beyond, and capable to compete…

Image and Video Processing · Electrical Eng. & Systems 2023-05-08 Elvira Fleig , Erik Bochinski , Thomas Sikora

Object-centric representations form the basis of human perception, and enable us to reason about the world and to systematically generalize to new settings. Currently, most works on unsupervised object discovery focus on slot-based…

Machine Learning · Computer Science 2022-11-21 Sindy Löwe , Phillip Lippe , Maja Rudolph , Max Welling

We built a novel Bayesian hierarchical survival model based on the somatic mutation profile of patients across 50 genes and 27 cancer types. The pan-cancer quality allows for the model to "borrow" information across cancer types, motivated…

Quantitative Methods · Quantitative Biology 2019-10-09 Sarah Samorodnitsky , Katherine A. Hoadley , Eric F. Lock

Zero-day attack detection plays a critical role in mitigating risks, protecting assets, and staying ahead in the evolving threat landscape. This study explores the application of stacked autoencoder (SAE), a type of artificial neural…

Cryptography and Security · Computer Science 2023-11-02 Mahmut Tokmak , Mike Nkongolo

In this paper we propose a semi-supervised variational autoencoder for classification of overall survival groups from tumor segmentation masks. The model can use the output of any tumor segmentation algorithm, removing all assumptions on…

Computer Vision and Pattern Recognition · Computer Science 2020-11-18 Sveinn Pálsson , Stefano Cerri , Andrea Dittadi , Koen Van Leemput

Pre-training strategies based on self-supervised learning (SSL) have proven to be effective pretext tasks for many downstream tasks in computer vision. Due to the significant disparity between medical and natural images, the application of…

Skin cancer is a crucial health issue that requires timely detection for higher survival rates. Traditional computer vision techniques face challenges in addressing the advanced variability of skin lesion features, a gap partially bridged…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Sibasish Dhibar

We propose a multi-resolution convolutional autoencoder (MrCAE) architecture that integrates and leverages three highly successful mathematical architectures: (i) multigrid methods, (ii) convolutional autoencoders and (iii) transfer…

Machine Learning · Computer Science 2020-04-13 Yuying Liu , Colin Ponce , Steven L. Brunton , J. Nathan Kutz

Recently, guided waves-based techniques have garnered increased attention from researchers in the field of Structural Health Monitoring (SHM) for damage detection and quantification. Extracting features that are sensitive to changes in…

Signal Processing · Electrical Eng. & Systems 2024-10-08 Yiming Fan , Fotis Kopsaftopoulos

Background: Cancers are highly heterogeneous with different subtypes. These subtypes often possess different genetic variants, present different pathological phenotypes, and most importantly, show various clinical outcomes such as varied…

Graphics · Computer Science 2014-07-09 Hao Ding , Chao Wang , Kun Huang , Raghu Machiraju
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