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A common approach to analyze a covariate-sample count matrix, an element of which represents how many times a covariate appears in a sample, is to factorize it under the Poisson likelihood. We show its limitation in capturing the tendency…

Methodology · Statistics 2017-10-06 Mingyuan Zhou

The intricate interplay between host organisms and their gut microbiota has catalyzed research into the microbiome's role in disease, shedding light on novel aspects of disease pathogenesis. However, the mechanisms through which the…

Methodology · Statistics 2024-02-20 Lei Fang , Yue Wang , Chenglong Ye

Survival analysis is an important area of medical research, yet existing models often struggle to balance simplicity with flexibility. Simple models require minimal adjustments but come with strong assumptions, while more flexible models…

Methodology · Statistics 2025-08-22 Peter Knaus , Daniel Winkler , Sebastian F. Schoppmann , Gerd Jomrich

Clinical investigators are increasingly interested in discovering computational biomarkers from short-term longitudinal omics data sets. This work focuses on Bayesian regression and variable selection for longitudinal omics datasets, which…

Methodology · Statistics 2025-05-20 Livia Popa , Sumanta Basu , Myung Hee Lee , Martin T. Wells

A key problem in computational sustainability is to understand the distribution of species across landscapes over time. This question gives rise to challenging large-scale prediction problems since (i) hundreds of species have to be…

Machine Learning · Computer Science 2020-11-02 Shufeng Kong , Junwen Bai , Jae Hee Lee , Di Chen , Andrew Allyn , Michelle Stuart , Malin Pinsky , Katherine Mills , Carla P. Gomes

Data increasingly take the form of a multi-way array, or tensor, in several biomedical domains. Such tensors are often incompletely observed. For example, we are motivated by longitudinal microbiome studies in which several timepoints are…

Methodology · Statistics 2024-11-01 Ziren Jiang , Gen Li , Eric F. Lock

Microbiome data are complex in nature, involving high dimensionality, compositionally, zero inflation, and taxonomic hierarchy. Compositional data reside in a simplex that does not admit the standard Euclidean geometry. Most existing…

Methodology · Statistics 2020-11-12 Gen Li , Yan Li , Kun Chen

During the semiconductor manufacturing process, predicting the yield of the semiconductor is an important problem. Early detection of defective product production in the manufacturing process can save huge production cost. The data…

Applications · Statistics 2021-08-03 Sewon Park , Kyeongwon Lee , Da-Eun Jeong , Heung-Kook Ko , Jaeyong Lee

A fully Bayesian approach is proposed for ultrahigh-dimensional nonparametric additive models in which the number of additive components may be larger than the sample size, though ideally the true model is believed to include only a small…

Methodology · Statistics 2013-09-24 Zuofeng Shang , Ping Li

Multivariate matched proportions (MMP) data appears in a variety of contexts including post-market surveillance of adverse events in pharmaceuticals, disease classification, and agreement between care providers. It consists of multiple sets…

Methodology · Statistics 2023-05-08 Mark J. Meyer , Haobo Cheng , Katherine Hobbs Knutson

Modeling sparse count data, which arise across numerous scientific fields, presents significant statistical challenges. This chapter addresses these challenges in the context of infectious disease prediction, with a focus on predicting…

Machine Learning · Statistics 2026-02-05 Edwin Fong , Lancelot F. James , Juho Lee

This paper introduces a rectified and renormalized Fisher-Bingham model for compositional data with zeros, motivated in part by the presence of zeros in microbiota studies. The approach represents compositions through a square-root…

Methodology · Statistics 2026-04-29 Eugene Han , Marahi Perez-Tamayo , Hannah D. Holscher , Ruoqing Zhu

Fossil-based palaeoclimate reconstruction is an important area of ecological science that has gained momentum in the backdrop of the global climate change debate. The hierarchical Bayesian paradigm provides an interesting platform for…

Applications · Statistics 2013-12-13 Sabyasachi Mukhopadhyay , Sourabh Bhattacharya

Gene-gene interactions are often regarded as playing significant roles in influencing variabilities of complex traits. Although much research has been devoted to this area, to date a comprehensive statistical model that addresses the…

Applications · Statistics 2018-04-18 Durba Bhattacharya , Sourabh Bhattacharya

Zero-inflated regression models have had wide application recently and have provenuseful in modeling data with many zeros. Zero-inflated Binomial (ZIB) regression model is an extension of the ordinary binomial distribution that takes into…

Statistics Theory · Mathematics 2021-05-04 Aba Diop , Demba Bocar Ba , Fatimata Lo

In all areas of human knowledge, datasets are increasing in both size and complexity, creating the need for richer statistical models. This trend is also true for economic data, where high-dimensional and nonlinear/nonparametric inference…

Econometrics · Economics 2021-12-23 Dimitris Korobilis , Kenichi Shimizu

Scientific practice typically involves repeatedly studying a system, each time trying to unravel a different perspective. In each study, the scientist may take measurements under different experimental conditions (interventions,…

Machine Learning · Statistics 2014-03-11 Sofia Triantafillou , Ioannis Tsamardinos

We present a flexible Bayesian semiparametric mixed model for longitudinal data analysis in the presence of potentially high-dimensional categorical covariates. Building on a novel hidden Markov tensor decomposition technique, our proposed…

Methodology · Statistics 2022-08-05 Giorgio Paulon , Peter Müller , Abhra Sarkar

In real-world clinical settings, data distributions evolve over time, with a continuous influx of new, limited disease cases. Therefore, class incremental learning is of great significance, i.e., deep learning models are required to learn…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Yifei Yao , Hanrong Zhang

We introduce a flexible and scalable class of Bayesian geostatistical models for discrete data, based on the class of nearest neighbor mixture transition distribution processes (NNMP), referred to as discrete NNMP. The proposed class…

Methodology · Statistics 2022-03-04 Xiaotian Zheng , Athanasios Kottas , Bruno Sansó