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The performance of supervised deep learning methods for medical image segmentation is often limited by the scarcity of labeled data. As a promising research direction, semi-supervised learning addresses this dilemma by leveraging unlabeled…

Image and Video Processing · Electrical Eng. & Systems 2024-05-13 Zihang Liu , Chunhui Zhao

Precision medicine aims for personalized prognosis and therapeutics by utilizing recent genome-scale high-throughput profiling techniques, including next-generation sequencing (NGS). However, translating NGS data faces several challenges.…

Bayesian deep learning (BDL) is a promising approach to achieve well-calibrated predictions on distribution-shifted data. Nevertheless, there exists no large-scale survey that evaluates recent SOTA methods on diverse, realistic, and…

Machine Learning · Computer Science 2023-10-26 Florian Seligmann , Philipp Becker , Michael Volpp , Gerhard Neumann

Although supervised deep-learning has achieved promising performance in medical image segmentation, many methods cannot generalize well on unseen data, limiting their real-world applicability. To address this problem, we propose a deep…

Image and Video Processing · Electrical Eng. & Systems 2022-06-10 Shangqi Gao , Hangqi Zhou , Yibo Gao , Xiahai Zhuang

Medical image segmentation is challenging due to the diversity of medical images and the lack of labeled data, which motivates recent developments in federated semi-supervised learning (FSSL) to leverage a large amount of unlabeled data…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Zhipeng Deng , Zhe Xu , Tsuyoshi Isshiki , Yefeng Zheng

The ever-increasing size of modern data sets combined with the difficulty of obtaining label information has made semi-supervised learning one of the problems of significant practical importance in modern data analysis. We revisit the…

Machine Learning · Computer Science 2014-11-06 Diederik P. Kingma , Danilo J. Rezende , Shakir Mohamed , Max Welling

Neural network based generative models with discriminative components are a powerful approach for semi-supervised learning. However, these techniques a) cannot account for model uncertainty in the estimation of the model's discriminative…

Machine Learning · Statistics 2017-06-30 Jonathan Gordon , José Miguel Hernández-Lobato

Training deep networks with limited labeled data while achieving a strong generalization ability is key in the quest to reduce human annotation efforts. This is the goal of semi-supervised learning, which exploits more widely available…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Daiqing Li , Junlin Yang , Karsten Kreis , Antonio Torralba , Sanja Fidler

Due to the cross-domain distribution shift aroused from diverse medical imaging systems, many deep learning segmentation methods fail to perform well on unseen data, which limits their real-world applicability. Recent works have shown the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-06 Shangqi Gao , Hangqi Zhou , Yibo Gao , Xiahai Zhuang

Deep generative models are rapidly gaining traction in medical imaging. Nonetheless, most generative architectures struggle to capture the underlying probability distributions of volumetric data, exhibit convergence problems, and offer no…

Machine Learning · Computer Science 2019-07-29 Guilherme Pombo , Robert Gray , Tom Varsavsky , John Ashburner , Parashkev Nachev

Image segmentation is important in medical imaging, providing valuable, quantitative information for clinical decision-making in diagnosis, therapy, and intervention. The state-of-the-art in automated segmentation remains supervised…

Computer Vision and Pattern Recognition · Computer Science 2023-04-28 Margherita Rosnati , Fabio De Sousa Ribeiro , Miguel Monteiro , Daniel Coelho de Castro , Ben Glocker

Traditional supervised medical image segmentation models require large amounts of labeled data for training; however, obtaining such large-scale labeled datasets in the real world is extremely challenging. Recent semi-supervised…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Yunyao Lu , Yihang Wu , Reem Kateb , Ahmad Chaddad

Despite the remarkable performance of supervised medical image segmentation models, relying on a large amount of labeled data is impractical in real-world situations. Semi-supervised learning approaches aim to alleviate this challenge using…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yunyao Lu , Yihang Wu , Ahmad Chaddad , Tareef Daqqaq , Reem Kateb

In medical image segmentation, supervised deep networks' success comes at the cost of requiring abundant labeled data. While asking domain experts to annotate only one or a few of the cohort's images is feasible, annotating all available…

Computer Vision and Pattern Recognition · Computer Science 2021-10-06 Devavrat Tomar , Behzad Bozorgtabar , Manana Lortkipanidze , Guillaume Vray , Mohammad Saeed Rad , Jean-Philippe Thiran

Semi-supervised learning relaxes the need of large pixel-wise labeled datasets for image segmentation by leveraging unlabeled data. The scarcity of high-quality labeled data remains a major challenge in medical image analysis due to the…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Jun Li

This paper concerns pseudo labelling in segmentation. Our contribution is fourfold. Firstly, we present a new formulation of pseudo-labelling as an Expectation-Maximization (EM) algorithm for clear statistical interpretation. Secondly, we…

Computer Vision and Pattern Recognition · Computer Science 2022-09-14 Mou-Cheng Xu , Yukun Zhou , Chen Jin , Marius de Groot , Daniel C. Alexander , Neil P. Oxtoby , Yipeng Hu , Joseph Jacob

Existing semi-supervised medical segmentation co-learning frameworks have realized that model performance can be diminished by the biases in model recognition caused by low-quality pseudo-labels. Due to the averaging nature of their…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Yuanpeng He , Yali Bi , Lijian Li , Chi-Man Pun , Wenpin Jiao , Zhi Jin

Supervised learning algorithms based on Convolutional Neural Networks have become the benchmark for medical image segmentation tasks, but their effectiveness heavily relies on a large amount of labeled data. However, annotating medical…

Image and Video Processing · Electrical Eng. & Systems 2023-11-20 Tao Wang , Yuanbin Chen , Xinlin Zhang , Yuanbo Zhou , Junlin Lan , Bizhe Bai , Tao Tan , Min Du , Qinquan Gao , Tong Tong

Medical image segmentation is critical for computer-aided diagnosis. However, dense pixel-level annotation is time-consuming and expensive, and medical datasets often exhibit severe class imbalance. Such imbalance causes minority structures…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Yingxue Su , Yiheng Zhong , Keying Zhu , Zimu Zhang , Zhuoru Zhang , Yifang Wang , Yuxin Zhang , Jingxin Liu

Volume-wise labeling in 3D medical images is a time-consuming task that requires expertise. As a result, there is growing interest in using semi-supervised learning (SSL) techniques to train models with limited labeled data. However, the…

Image and Video Processing · Electrical Eng. & Systems 2023-10-18 Haonan Wang , Xiaomeng Li
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