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Non-equilibrium fluctuations of various stochastic variables, such as work and entropy production, have been widely discussed recently in the context of large deviations, cumulants and fluctuation relations. Typically, one looks at the…

Statistical Mechanics · Physics 2016-08-03 Keiji Saito , Abhishek Dhar

Gene expression is inherently a noisy process which manifests as cell-to-cell variability in time evolution of proteins. Consequently, events that trigger at critical threshold levels of regulatory proteins exhibit stochasticity in their…

Subcellular Processes · Quantitative Biology 2016-09-26 Khem Raj Ghusinga , Abhyudai Singh

The stochastic motion of particles in living cells is often spatially inhomogeneous with a higher effective diffusivity in a region close to the cell boundary due to active transport along actin filaments. As a first step to understand the…

Statistical Mechanics · Physics 2019-09-25 Matthieu Mangeat , Heiko Rieger

In this paper, we consider the problem of mean first-passage time (MFPT) in quantum mechanics; the MFPT is the average time of the transition from a given initial state, passing through some intermediate states, to a given final state for…

Statistical Mechanics · Physics 2015-06-11 Rong-Tao Qiu , Wu-Sheng Dai , Mi Xie

We review some representative results for first-passage problems involving so-called mortal or evanescent walkers, i.e., walkers with a finite lifetime. The mortality constraint plays a key role in the modeling of many real scenarios, as it…

Statistical Mechanics · Physics 2024-10-22 E. Abad , S. B. Yuste

A key part of any evolutionary algorithm is fitness evaluation. When fitness evaluations are corrupted by noise, as happens in many real-world problems as a consequence of various types of uncertainty, a strategy is needed in order to cope…

Neural and Evolutionary Computing · Computer Science 2017-07-13 Simon M. Lucas , Jialin Liu , Diego Pérez-Liébana

The idea that the search efficiency can be increased with the help of a number of autonomous agents is often relevant in many situations, which is known among biologists and roboticists as a stigmergy. This is due to the fact that, in any…

Quantum Physics · Physics 2019-09-17 Jin-Hui Zhu , Li-Hua Lu , You-Quan Li

We study the mean first passage time of a one-dimensional random walker with step sizes decaying exponentially in discrete time. That is step sizes go like $\lambda^{n}$ with $\lambda\leq1$ . We also present, for pedagogical purposes, a…

Statistical Mechanics · Physics 2009-11-10 Tonguç Rador , Sencer Taneri

Single file systems are simplified models to study effectively one-dimensional physical systems. Here we compute analytically the complete first exit time statistics for an ideal overdamped single file with absorbing boundary conditions.…

Statistical Mechanics · Physics 2022-05-06 Alessio Lapolla

Understanding the topological characteristics of complex networks and how they affect navigability is one of the most important goals in science today, as it plays a central role in various economic, biological, ecological and social…

Physics and Society · Physics 2020-04-29 M. S. Chaves , T. G. Mattos , A. P. F. Atman

Resetting is a strategy for boosting the speed of a target-searching process. Since its introduction over a decade ago, most studies have been carried out under the assumption that resetting takes place instantaneously. However, due to its…

Statistical Mechanics · Physics 2023-05-09 Priyo Shankar Pal , Arnab Pal , Hyunggyu Park , Jae Sung Lee

The fitness of a biological strategy is typically measured by its expected reproductive rate, the first moment of its offspring distribution. However, strategies with high expected rates can also have high probabilities of extinction. A…

Populations and Evolution · Quantitative Biology 2013-05-17 Sterling Sawaya , Steffen Klaere

We study the time until first occurrence, the first-passage time, of rare density fluctuations in diffusive systems. We approach the problem using a model consisting of many independent random walkers on a lattice. The existence of spatial…

Statistical Mechanics · Physics 2008-05-16 David P. Sanders , Hernán Larralde

Molecular dynamics simulations have become essential in many areas of atomistic modelling from drug discovery to materials science. They provide critical atomic-level insights into key dynamical events experiments cannot easily capture.…

Biological Physics · Physics 2024-06-14 Tiejun Wei , Balint Dudas , Edina Rosta

How much time does it take for a fluctuating system, such as a polymer chain, to reach a target configuration that is rarely visited -- typically because of a high energy cost ? This question generally amounts to the determination of the…

Statistical Mechanics · Physics 2020-03-18 Nicolas Levernier , Olivier Bénichou , Raphaël Voituriez , Thomas Guérin

In the classical context, it is well known that, sometimes, if the search does not find its target, it is better to start the process anew again, known as resetting. The quantum counterpart of resetting also indicates speeding up the…

Quantum Physics · Physics 2024-10-01 Pallabi Chatterjee , S. Aravinda , Ranjan Modak

Shortest Remaining Processing Time (SRPT) is a well known preemptive scheduling algorithm for uniprocessor and multiprocessor systems. SRPT finds applications in the emerging areas such as scheduling of client's requests that are submitted…

Data Structures and Algorithms · Computer Science 2020-12-21 Sheetal Swain , Rakesh Mohanty , Debasis Dwibedy

Random search processes are instrumental in studying and understanding navigation properties of complex networks, food search strategies of animals, diffusion control of molecular processes in biological cells, and improving web search…

Social and Information Networks · Computer Science 2016-01-27 Igor Trpevski , Ljupco Kocarev

Thermally activated escape of an over-damped particle from a metastable well under the action of a time-ramped force is studied. We express the mean first passage time (MFPT) as the solution to a partial differential equation, which we…

Statistical Mechanics · Physics 2009-10-31 Julian Shillcock , Udo Seifert

Stochastic resets have lately emerged as a mechanism able to generate finite equilibrium mean square displacement (MSD) when they are applied to diffusive motion. Furthermore, walkers with an infinite mean first arrival time (MFAT) to a…

Statistical Mechanics · Physics 2019-02-06 Axel Masó-Puigdellosas , Daniel Campos , Vicenç Méndez