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The dynamics of molecular motors which occasionally detach from a heterogeneous track like DNA or RNA is considered. Motivated by recent single molecule experiments, we study a simple model for a motor moving along a disordered track using…

Statistical Mechanics · Physics 2009-11-10 Yariv Kafri , David K. Lubensky , David R. Nelson

The stochastic driving force exerted by a single molecular motor (e.g., a kinesin, or myosin) moving on a periodic molecular track (microtubule, actin filament, etc.) is discussed from a general viewpoint open to experimental test. An…

Statistical Mechanics · Physics 2009-10-31 Michael E. Fisher , Anatoly B. Kolomeisky

Dynamic properties of molecular motors that fuel their motion by actively interacting with underlying molecular tracks are studied theoretically via discrete-state stochastic ``burnt-bridge'' models. The transport of the particles is viewed…

Soft Condensed Matter · Physics 2009-11-13 Maxim N. Artyomov , Alexander Yu. Morozov , Ekaterina Pronina , Anatoly B. Kolomeisky

Torque is ubiquitous in many molecular systems, including collisions, chemical reactions, vibrations, electronic excitations and especially rotor molecules. We present a straightforward theoretical method based on forces acting on atoms and…

Chemical Physics · Physics 2016-11-23 Rui-Qin Zhang , Yan-Ling Zhao , Fei Qi , Klaus Hermann , Michel A. Van Hove

We study the dynamical response of a circularly-driven rigid body, focusing on the description of intrinsic rotational behavior (reverse rotations). The model system we address is integrable but nontrivial, allowing for qualitative and…

Classical Physics · Physics 2009-11-13 Fernando Parisio

A molecular motor is made of either a single macromolecule or a macromolecular complex. Just like their macroscopic counterparts, molecular motors "transduce" input energy into mechanical work. All the nano-motors considered here operate…

Biological Physics · Physics 2013-07-18 Debashish Chowdhury

Transport of molecular motors, stimulated by interactions with specific links between consecutive binding sites (called ``bridges''), is investigated theoretically by analyzing discrete-state stochastic ``burnt-bridge'' models. When an…

Soft Condensed Matter · Physics 2015-06-25 Alexander Yu. Morozov , Ekaterina Pronina , Anatoly B. Kolomeisky , Maxim N. Artyomov

Self-propelled chemically powered synthetic micron and nano-scale motors are being intensively studied because of the wide range of potential applications that exploit their directed motion. This paper considers even smaller…

Soft Condensed Matter · Physics 2015-11-17 Peter H. Colberg , Raymond Kapral

We study a model of synthetic molecular motor - a [3]-catenane consisting of two small macrocycles mechanically interlocked with a bigger one - subjected to a time-dependent driving using stochastic thermodynamics. The model presents…

Statistical Mechanics · Physics 2023-06-28 Massimo Bilancioni , Massimiliano Esposito , Emanuele Penocchio

Manipulating and coupling molecule gears is the first step towards realizing molecular-scale mechanical machines. Here, we theoretically investigate the behavior of such gears using molecular dynamics simulations. Within a nearly rigid-body…

Soft Condensed Matter · Physics 2020-03-12 H. -H. Lin , A. Croy , R. Gutierrez , C. Joachim , G. Cuniberti

The dynamics of a spherical chemically-powered synthetic colloidal motor that operates by a self-diffusiophoretic mechanism and has a catalytic domain of arbitrary shape is studied using both continuum theory and particle-based simulations.…

Soft Condensed Matter · Physics 2019-12-17 Shang Yik Reigh , Mu-Jie Huang , Hartmut Löwen , Eric Lauga , Raymond Kapral

On the basis of the transport features and experimental phenomena observed in studies of molecular motors, we proposea double-temperature ratchet model of coupled motors to reveal the dynamical mechanism of cooperative transport of motors…

Classical Physics · Physics 2017-02-24 Chen-pu Li , Hong-bin Chen , Zhi-gang Zheng

The transport by molecular motors along cytoskeletal filaments is studied theoretically in the presence of static defects. The movements of single motors are described as biased random walks along the filament as well as binding to and…

Biological Physics · Physics 2009-05-08 Yan Chai , Reinhard Lipowsky , Stefan Klumpp

Biological functions in each animal cell depend on coordinated operations of a wide variety of molecular motors. Some of the these motors transport cargo to their respective destinations whereas some others are mobile workshops which…

Biological Physics · Physics 2008-03-07 Debashish Chowdhury

The collective dynamics of $N$ weakly coupled processive molecular motors are considered theoretically. We show, using a discrete lattice model, that the velocity-force curves strongly depend on the effective dynamic interactions between…

Subcellular Processes · Quantitative Biology 2009-11-11 O. Campas , Y. Kafri , K. B. Zeldovich , J. Casademunt , J. -F. Joanny

Many biological processes are supported by special molecules, called motor proteins or molecular motors, that transport cellular cargoes along linear protein filaments and can reversibly associate to their tracks. Stimulated by these…

Statistical Mechanics · Physics 2021-11-17 Akriti Jindal , Anatoly B. Kolomeisky , Arvind Kumar Gupta

A scanning tunneling microscope can probe the inelastic spin excitations of a single magnetic atom in a surface via spin-flip assisted tunneling in which transport electrons exchange spin and energy with the atomic spin. If the inelastic…

Mesoscale and Nanoscale Physics · Physics 2015-05-19 F. Delgado , J. Fernández-Rossier

Enzymatic molecules that actively support many cellular processes, including transport, cell division and cell motility, are known as motor proteins or molecular motors. Experimental studies indicate that they interact with each other and…

Biological Physics · Physics 2015-05-20 Daniel Celis-Garza , Hamid Teimouri , Anatoly B. Kolomeisky

We introduce a new scheme for controlling the sense of molecular rotation. By varying the polarization and the delay between two ultrashort laser pulses, we induce unidirectional molecular rotation, thereby forcing the molecules to rotate…

Quantum Physics · Physics 2015-05-13 Sharly Fleischer , Yuri Khodorkovsky , Yehiam Prior , Ilya Sh. Averbukh

Using molecular dynamics simulations, we study particle-transport in a system of interacting colloidal particles on a ring, where the system is driven by a time-dependent external potential, moving along the ring. We consider two driving…

Statistical Mechanics · Physics 2018-12-06 Shubhashis Rana , Sanchari Goswami , Sakuntala Chatterjee , Punyabrata Pradhan