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Complex, high-dimensional data is ubiquitous across many scientific disciplines, including machine learning, biology, and the social sciences. One of the primary methods of visualizing these datasets is with two-dimensional scatter plots…

Machine Learning · Computer Science 2025-10-13 Kiran Smelser , Kaviru Gunaratne , Jacob Miller , Stephen Kobourov

High-dimensional Bayesian procedures often exhibit behavior that is effectively low dimensional, even when the ambient parameter space is large or infinite-dimensional. This phenomenon underlies the success of shrinkage priors,…

Statistics Theory · Mathematics 2025-12-30 Sayantan Banerjee

Mutual information is an important measure of the dependence among variables. It has become widely used in statistics, machine learning, biology, etc. However, the standard techniques for estimating it often perform poorly in higher…

Data Analysis, Statistics and Probability · Physics 2023-09-18 Nick Carrara , Jesse Ernst

A new dimension reduction method based on Gaussian finite mixtures is proposed as an extension to sliced inverse regression (SIR). The model-based SIR (MSIR) approach allows the main limitation of SIR to be overcome, i.e., failure in the…

Methodology · Statistics 2015-08-11 Luca Scrucca

We define a metric, mutual information in frequency (MI-in-frequency), to detect and quantify the statistical dependence between different frequency components in the data, referred to as cross-frequency coupling and apply it to…

Neurons and Cognition · Quantitative Biology 2018-05-23 Rakesh Malladi , Don H Johnson , Giridhar P Kalamangalam , Nitin Tandon , Behnaam Aazhang

We study some of the most commonly used mutual information estimators, based on histograms of fixed or adaptive bin size, $k$-nearest neighbors and kernels, and focus on optimal selection of their free parameters. We examine the consistency…

Data Analysis, Statistics and Probability · Physics 2015-05-13 Angeliki Papana , Dimitris Kugiumtzis

As a fundamental concept in information theory, mutual information ($MI$) has been commonly applied to quantify association between random vectors. Most existing nonparametric estimators of $MI$ have unstable statistical performance since…

Applications · Statistics 2025-02-19 Soumik Purkayastha , Peter X. K. Song

We introduce a novel Mutual Information (MI) estimator that fundamentally reframes the discriminative approach. Instead of training a classifier to discriminate between joint and marginal distributions, we learn a normalizing flow that…

Machine Learning · Computer Science 2026-02-10 Ivan Butakov , Alexander Semenenko , Valeriya Kirova , Alexey Frolov , Ivan Oseledets

Informative interim adaptations lead to random sample sizes. The random sample size becomes a component of the sufficient statistic and estimation based solely on observed samples or on the likelihood function does not use all available…

Methodology · Statistics 2022-10-25 Sergey Tarima , Nancy Flournoy

Real-space mutual information (RSMI) was shown to be an important quantity, formally and from a numerical standpoint, in finding coarse-grained descriptions of physical systems. It very generally quantifies spatial correlations, and can…

Statistical Mechanics · Physics 2021-12-09 Doruk Efe Gökmen , Zohar Ringel , Sebastian D. Huber , Maciej Koch-Janusz

In the last decade, recent successes in deep clustering majorly involved the mutual information (MI) as an unsupervised objective for training neural networks with increasing regularisations. While the quality of the regularisations have…

Several methods are available for the detection of covarying positions from a multiple sequence alignment (MSA). If the MSA contains a large number of sequences, information about the proximities between residues derived from covariation…

Quantitative Methods · Quantitative Biology 2014-04-29 Greg W. Clark , Sharon H. Ackerman , Elisabeth R. Tillier , Domenico L. Gatti

This paper is devoted to the mathematical study of some divergences based on the mutual information well-suited to categorical random vectors. These divergences are generalizations of the "entropy distance" and "information distance". Their…

Statistics Theory · Mathematics 2016-08-16 Jean-François Coeurjolly , Rémy Drouilhet , Jean-François Robineau

Reshef & Reshef recently published a paper in which they present a method called the Maximal Information Coefficient (MIC) that can detect all forms of statistical dependence between pairs of variables as sample size goes to infinity. While…

Machine Learning · Statistics 2013-08-28 Alexander Luedtke , Linh Tran

Magnetic Resonance Imaging (MRI) scans are time consuming and precarious, since the patients remain still in a confined space for extended periods of time. To reduce scanning time, some experts have experimented with undersampled k spaces,…

Image and Video Processing · Electrical Eng. & Systems 2022-08-25 Kyler Larsen , Arghya Pal , Yogesh Rathi

Existing sequence alignment algorithms use heuristic scoring schemes which cannot be used as objective distance metrics. Therefore one relies on measures like the p- or log-det distances, or makes explicit, and often simplistic, assumptions…

Genomics · Quantitative Biology 2015-05-19 Orion Penner , Peter Grassberger , Maya Paczuski

Self-supervised sequential recommendation significantly improves recommendation performance by maximizing mutual information with well-designed data augmentations. However, the mutual information estimation is based on the calculation of…

Machine Learning · Computer Science 2023-06-21 Ziwei Fan , Zhiwei Liu , Hao Peng , Philip S Yu

We propose to use precise estimators of mutual information (MI) to find least dependent components in a linearly mixed signal. On the one hand this seems to lead to better blind source separation than with any other presently available…

Computational Physics · Physics 2007-07-16 Harald Stögbauer , Alexander Kraskov , Sergey A. Astakhov , Peter Grassberger

The failure of deep neural networks to generalize to out-of-distribution data is a well-known problem and raises concerns about the deployment of trained networks in safety-critical domains such as healthcare, finance and autonomous…

Machine Learning · Computer Science 2022-06-28 Mohammed Adnan , Yani Ioannou , Chuan-Yung Tsai , Angus Galloway , H. R. Tizhoosh , Graham W. Taylor

Clustering is a concept used in a huge variety of applications. We review a conceptually very simple algorithm for hierarchical clustering called in the following the {\it mutual information clustering} (MIC) algorithm. It uses mutual…

Quantitative Methods · Quantitative Biology 2008-09-10 Alexander Kraskov , Peter Grassberger