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Head and neck cancer (HNC) patients who undergo radiotherapy (RT) may experience anatomical changes during treatment, compromising the validity of the initial treatment plan, necessitating replanning. However, replanning disrupts clinical…

Automatic non-invasive assessment of hepatocellular carcinoma (HCC) malignancy has the potential to substantially enhance tumor treatment strategies for HCC patients. In this work we present a novel framework to automatically characterize…

Segmentation of head and neck (H\&N) tumours and prediction of patient outcome are crucial for patient's disease diagnosis and treatment monitoring. Current developments of robust deep learning models are hindered by the lack of large…

Image and Video Processing · Electrical Eng. & Systems 2021-11-09 Emmanuelle Bourigault , Daniel R. McGowan , Abolfazl Mehranian , Bartłomiej W. Papież

Molecular subtypes of breast cancer are important references to personalized clinical treatment. For cost and labor savings, only one of the patient's paraffin blocks is usually selected for subsequent immunohistochemistry (IHC) to obtain…

Image and Video Processing · Electrical Eng. & Systems 2022-03-16 Hong Liu , Wen-Dong Xu , Zi-Hao Shang , Xiang-Dong Wang , Hai-Yan Zhou , Ke-Wen Ma , Huan Zhou , Jia-Lin Qi , Jia-Rui Jiang , Li-Lan Tan , Hui-Min Zeng , Hui-Juan Cai , Kuan-Song Wang , Yue-Liang Qian

Simultaneous segmentation and classification of nuclei in digital histology play an essential role in computer-assisted cancer diagnosis; however, it remains challenging. The highest achieved binary and multi-class Panoptic Quality (PQ)…

Computer Vision and Pattern Recognition · Computer Science 2024-04-29 Ibtihaj Ahmad , Syed Muhammad Israr , Zain Ul Islam

Accurate survival prediction in head and neck cancer (HNC) is essential for guiding clinical decision-making and optimizing treatment strategies. Traditional models, such as Cox proportional hazards, have been widely used but are limited in…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Aiman Farooq , Utkarsh Sharma , Deepak Mishra

Lung adenocarcinoma is a morphologically heterogeneous disease, characterized by five primary histologic growth patterns. The quantity of these patterns can be related to tumor behavior and has a significant impact on patient prognosis. In…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Arwa Al-Rubaian , Gozde N. Gunesli , Wajd A. Althakfi , Ayesha Azam , Nasir Rajpoot , Shan E Ahmed Raza

Human papillomavirus (HPV) infection is the most common sexually transmitted infection in the world. Persistent oncogenic Human papillomavirus infection has been a leading threat to global health and can lead to serious complications such…

Populations and Evolution · Quantitative Biology 2024-11-13 Weiyi Wang , Shailendra Sawleshwarkar , Mahendra Piraveenan

Semantic segmentation of electron microscopy (EM) is an essential step to efficiently obtain reliable morphological statistics. Despite the great success achieved using deep convolutional neural networks (CNNs), they still produce coarse…

Computer Vision and Pattern Recognition · Computer Science 2021-01-11 Zhimin Yuan , Xiaofen Ma , Jiajin Yi , Zhengrong Luo , Jialin Peng

The diagnosis of primary liver cancers (PLCs) can be challenging, especially on biopsies and for combined hepatocellular-cholangiocarcinoma (cHCC-CCA). We automatically classified PLCs on routine-stained biopsies using a weakly supervised…

Accurate survival predicting models are essential for improving targeted cancer therapies and clinical care among cancer patients. In this article, we investigate and develop a method to improve predictions of survival in cancer by…

Methodology · Statistics 2025-06-30 Eun Jeong Oh , Seungjun Ahn , Tristan Tham , Min Qian

A two-layer neural network model that systematically includes correlations among input variables to arbitrary order and is designed to implement Bayes inference has been adapted to classify breast cancer tumors as malignant or benign,…

Machine Learning · Computer Science 2019-12-17 Aditya Cowsik , John W. Clark

We present an effective application of quantum machine learning in the field of healthcare. The study here emphasizes on a classification problem of a histopathological cancer detection using quantum transfer learning. Rather than using…

Quantum Physics · Physics 2023-02-10 Reek Majumdar , Biswaraj Baral , Bhavika Bhalgamiya , Taposh Dutta Roy

Molecular and genomic properties are critical in selecting cancer treatments to target individual tumors, particularly for immunotherapy. However, the methods to assess such properties are expensive, time-consuming, and often not routinely…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Heather D. Couture

Histopathological images provide rich information for disease diagnosis. Large numbers of histopathological images have been digitized into high resolution whole slide images, opening opportunities in developing computational image analysis…

Image and Video Processing · Electrical Eng. & Systems 2020-11-06 Jiayun Li , Wenyuan Li , Anthony Sisk , Huihui Ye , W. Dean Wallace , William Speier , Corey W. Arnold

Locoregional recurrences (LRR) are still a frequent site of treatment failure for head and neck squamous cell carcinoma (HNSCC) patients. Identification of high risk subvolumes based on pretreatment imaging is key to biologically targeted…

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide. Whole-slide imaging which is a method of scanning glass slides have been employed for diagnosis of HCC. Using high resolution Whole-slide images is…

Computer Vision and Pattern Recognition · Computer Science 2020-02-20 Mehmet Burak Sayıcı , Rikiya Yamashita , Jeanne Shen

According to GLOBOCAN 2020, prostate cancer is the second most common cancer in men worldwide and the fourth most prevalent cancer overall. For pathologists, grading prostate cancer is challenging, especially when discriminating between…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Zahra Tabatabaei , Adrian colomer , Kjersti Engan , Javier Oliver , Valery Naranjo

Understanding the way cells communicate, co-locate, and interrelate is essential to furthering our understanding of how the body functions. H&E is widely available, however, cell subtyping often requires expert knowledge and the use of…

Nuclei instance segmentation is crucial in oncological diagnosis and cancer pathology research. H&E stained images are commonly used for medical diagnosis, but pre-processing is necessary before using them for image processing tasks. Two…

Image and Video Processing · Electrical Eng. & Systems 2024-04-22 Zarif Ahmed , Chowdhury Nur E Alam Siddiqi , Fardifa Fathmiul Alam , Tasnim Ahmed , Tareque Mohmud Chowdhury