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We introduce a computational efficient data-driven framework suitable for quantifying the uncertainty in physical parameters and model formulation of computer models, represented by differential equations. We construct physics-informed…

Machine Learning · Statistics 2023-02-01 Michail Spitieris , Ingelin Steinsland

Emerging from NASA's spacecraft simulations in the 1960s, digital twin technology has advanced through industrial adoption to spark a healthcare transformation. A digital twin is a dynamic, data-driven virtual counterpart of a physical…

Artificial Intelligence · Computer Science 2025-11-27 Yunqi Zhang , Kuangyu Shi , Biao Li

Digital twins have attracted a great deal of recent attention from a wide range of fields. A basic requirement for digital twins of nonlinear dynamical systems is the ability to generate the system evolution and predict potentially…

Machine Learning · Computer Science 2023-09-21 Ying-Cheng Lai

We consider a human-assisted autonomy sensor fusion for dynamic target localization in a Bayesian framework. Autonomous sensor-based tracking systems can suffer from observability and target detection failure. Humans possess valuable…

Robotics · Computer Science 2024-10-08 Min-Won Seo , Solmaz S. Kia

Realizing the potential gains of large-scale MIMO systems requires the accurate estimation of their channels or the fine adjustment of their narrow beams. This, however, is typically associated with high channel acquisition/beam sweeping…

Signal Processing · Electrical Eng. & Systems 2023-01-19 Shuaifeng Jiang , Ahmed Alkhateeb

Modern manufacturing systems often experience multiple and unpredictable failure behaviors, yet most existing prognostic models assume a fixed, known set of failure modes with labeled historical data. This assumption limits the use of…

Applications · Statistics 2026-02-24 Kani Fu , Sanduni S Disanayaka Mudiyanselage , Chunli Dai , Minhee Kim

From the nano-scale to the macro-scale, biological tissue is spatially heterogeneous. Even when tissue behavior is well understood, the exact subject specific spatial distribution of material properties is often unknown. And, when…

Tissues and Organs · Quantitative Biology 2020-11-02 Emma Lejeune , Bill Zhao

This article presents the guided Bayesian optimization algorithm as an efficient data-driven method for iteratively tuning closed-loop controller parameters using an event-triggered digital twin of the system based on available closed-loop…

Systems and Control · Electrical Eng. & Systems 2025-11-05 Mahdi Nobar , Jürg Keller , Alisa Rupenyan , Mohammad Khosravi , John Lygeros

A comprehensive artificial intelligence system needs to not only perceive the environment with different `senses' (e.g., seeing and hearing) but also infer the world's conditional (or even causal) relations and corresponding uncertainty.…

Machine Learning · Statistics 2021-01-07 Hao Wang , Dit-Yan Yeung

The objective of personalized medicine is to tailor interventions to an individual patient's unique characteristics. A key technology for this purpose involves medical digital twins, computational models of human biology that can be…

Quantitative Methods · Quantitative Biology 2024-03-22 Lucas Böttcher , Luis L. Fonseca , Reinhard C. Laubenbacher

Inspired by the digital twinning systems, a novel real-time digital double framework is developed to enhance robot perception of the terrain conditions. Based on the very same physical model and motion control, this work exploits the use of…

Digital twin (DT) technologies have emerged as a solution for real-time data-driven modeling of cyber physical systems (CPS) using the vast amount of data available by Internet of Things (IoT) networks. In this position paper, we elucidate…

Networking and Internet Architecture · Computer Science 2022-04-12 Jithin Jagannath , Keyvan Ramezanpour , Anu Jagannath

Digital twins are meant to bridge the gap between real-world physical systems and virtual representations. Both stand-alone and descriptive digital twins incorporate 3D geometric models, which are the physical representations of objects in…

Computer Vision and Pattern Recognition · Computer Science 2021-03-16 Tiril Sundby , Julia Maria Graham , Adil Rasheed , Mandar Tabib , Omer San

A multi-fidelity simulator is a numerical model, in which one of the inputs controls a trade-off between the realism and the computational cost of the simulation. Our goal is to estimate the probability of exceeding a given threshold on a…

Methodology · Statistics 2021-03-31 Rémi Stroh , Julien Bect , Séverine Demeyer , Nicolas Fischer , Emmanuel Vazquez

The convergence of modeling & simulation (M&S) and artificial intelligence (AI) is leaving its marks on advanced digital technology. Pertinent examples are digital twins (DTs) - high-fidelity, live representations of physical assets, and…

Artificial Intelligence · Computer Science 2026-02-24 Philipp Zech , Istvan David

The potential of digital twin technology is immense, specifically in the infrastructure, aerospace, and automotive sector. However, practical implementation of this technology is not at an expected speed, specifically because of lack of…

Machine Learning · Statistics 2021-03-30 Shailesh Garg , Ankush Gogoi , Souvik Chakraborty , Budhaditya Hazra

Mathematical models of cognition are often memoryless and ignore potential fluctuations of their parameters. However, human cognition is inherently dynamic. Thus, we propose to augment mechanistic cognitive models with a temporal dimension…

The development of Digital Twins (DTs) represents a transformative advance for simulating and optimizing complex systems in a controlled digital space. Despite their potential, the challenge of constructing DTs that accurately replicate and…

Systems and Control · Electrical Eng. & Systems 2024-06-21 Longfei Ma , Nan Cheng , Xiucheng Wang , Jiong Chen , Yinjun Gao , Dongxiao Zhang , Jun-Jie Zhang

Data-driven approaches achieve remarkable results for the modeling of complex dynamics based on collected data. However, these models often neglect basic physical principles which determine the behavior of any real-world system. This…

Systems and Control · Electrical Eng. & Systems 2023-05-17 Thomas Beckers , Jacob Seidman , Paris Perdikaris , George J. Pappas

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…