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Micro-Electro-Mechanical-Systems are complex structures, often involving nonlinearites of geometric and multiphysics nature, that are used as sensors and actuators in countless applications. Starting from full-order representations, we…

Dynamical Systems · Mathematics 2023-04-04 Giorgio Gobat , Stefania Fresca , Andrea Manzoni , Attilio Frangi

Digital twins, as precise digital representations of physical systems, have evolved from passive simulation tools into intelligent and autonomous entities through the integration of artificial intelligence technologies. This paper presents…

Multi-fidelity machine learning methods address the accuracy-efficiency trade-off by integrating scarce, resource-intensive high-fidelity data with abundant but less accurate low-fidelity data. We propose a practical multi-fidelity strategy…

Machine Learning · Computer Science 2025-03-26 Jiaxiang Yi , Ji Cheng , Miguel A. Bessa

The Digital Twins concept in science has a long history that goes back to the beginnings of now widely accepted modelling. The ever-expanding amount of digital data accompanying modelling could not but cause a qualitative transition from…

Materials Science · Physics 2022-09-01 Elena F. Sheka

Scientific advancement is universally based on the dynamic interplay between theoretical insights, modelling, and experimental discoveries. However, this feedback loop is often slow, including delayed community interactions and the gradual…

Medical digital twins are computational models of human biology relevant to a given medical condition, which can be tailored to an individual patient, thereby predicting the course of disease and individualized treatments, an important goal…

Systems for transport and processing of granular media are challenging to analyse, operate and optimise. In the mining and mineral processing industries these systems are chains of processes with complex interplay between the equipment,…

Computational Engineering, Finance, and Science · Computer Science 2021-04-20 Martin Servin , Folke Vesterlund , Erik Wallin

The concept of a digital twin has exploded in popularity over the past decade, yet confusion around its plurality of definitions, its novelty as a new technology, and its practical applicability still exists, all despite numerous reviews,…

Machine Learning · Computer Science 2022-06-27 Brian Kunzer , Mario Berges , Artur Dubrawski

What do data tell us about physics-and what don't they tell us? There has been a surge of interest in using machine learning models to discover governing physical laws such as differential equations from data, but current methods lack…

Machine Learning · Computer Science 2020-06-09 Steven Atkinson

The concept of creating a virtual copy of a complete Cyber-Physical System opens up numerous possibilities, including real-time assessments of the physical environment and continuous learning from the system to provide reliable and precise…

Artificial Intelligence · Computer Science 2023-11-22 Carine Menezes Rebello , Johannes Jäschkea , Idelfonso B. R. Nogueira

Digital twins of sensory cortex serve as powerful response oracles. Although prediction accuracy is the central metric by which these models are evaluated, it provides limited insight into the latent representations that support those…

Neurons and Cognition · Quantitative Biology 2026-05-28 Adriano Lima , Yuchen Hou , Michael Beyeler , Marius Schneider

Assimilation of continuously streamed monitored data is an essential component of a digital twin; the assimilated data are used to ensure the digital twin is a true representation of the monitored system. One way this is achieved is by…

Computational Engineering, Finance, and Science · Computer Science 2021-05-11 Rebecca Ward , Ruchi Choudhary , Alastair Gregory , Melanie Jans-Singh , Mark Girolami

Digital Twins (DTs) are virtual representations of physical systems synchronized in real time through Internet of Things (IoT) sensors and computational models. In industrial applications, DTs enable predictive maintenance, fault diagnosis,…

Other Computer Science · Computer Science 2025-07-18 Ali Mohammad-Djafari

One of the challenges in twinned systems is ensuring the digital twin remains a valid representation of the system it twins. Depending on the type of twinning occurring, it is either trivial, such as in dashboarding/visualizations that…

Software Engineering · Computer Science 2025-12-05 Joost Mertens , Joachim Denil

A digital twin can be defined as an adaptive model of a complex physical system. Recent advances in computational pipelines, multiphysics solvers, artificial intelligence, big data cybernetics, data processing and management tools bring the…

Signal Processing · Electrical Eng. & Systems 2019-10-07 Adil Rasheed , Omer San , Trond Kvamsdal

Calibration of dynamic models to data is an important step in building building digital twins of HVAC equipment, thermal loads and control systems. Sometimes, when a model fails to calibrate to data, a possible cause is that the model has…

Computational Engineering, Finance, and Science · Computer Science 2026-03-18 Sebastian Micluta-Campeanu , Avinash Subramanian , Anas Abdelrehim , Ranjan Anantharaman , Rohit Dhumane , Brad Carman , Chris Rackauckas

Over the past decade, scientific machine learning has transformed the development of mathematical and computational frameworks for analyzing, modeling, and predicting complex systems. From inverse problems to numerical PDEs, dynamical…

Machine Learning · Computer Science 2025-09-26 Matthias Chung , Deepanshu Verma , Max Collins , Amit N. Subrahmanya , Varuni Katti Sastry , Vishwas Rao

This paper presents a novel methodological framework, called the Actor-Simulator, that incorporates the calibration of digital twins into model-based reinforcement learning for more effective control of stochastic systems with complex…

Machine Learning · Computer Science 2025-01-07 Hua Zheng , Wei Xie , Ilya O. Ryzhov , Keilung Choy

Recent advances in modeling large-scale complex physical systems have shifted research focuses towards data-driven techniques. However, generating datasets by simulating complex systems can require significant computational resources.…

Machine Learning · Statistics 2022-08-22 Subhayan De , Matthew Reynolds , Malik Hassanaly , Ryan N. King , Alireza Doostan

The digital twin concept represents an appealing opportunity to advance condition-based and predictive maintenance paradigms for civil engineering systems, thus allowing reduced lifecycle costs, increased system safety, and increased system…

Numerical Analysis · Mathematics 2023-11-10 Matteo Torzoni , Marco Tezzele , Stefano Mariani , Andrea Manzoni , Karen E. Willcox