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Randomized experiments have been used to assist decision-making in many areas. They help people select the optimal treatment for the test population with certain statistical guarantee. However, subjects can show significant heterogeneity in…

Artificial Intelligence · Computer Science 2017-05-25 Yan Zhao , Xiao Fang , David Simchi-Levi

Recently, advances in machine learning techniques have attracted the attention of the research community to build intrusion detection systems (IDS) that can detect anomalies in the network traffic. Most of the research works, however, do…

Cryptography and Security · Computer Science 2018-12-14 Tara Salman , Deval Bhamare , Aiman Erbad , Raj Jain , Mohammed Samaka

Uplift modeling is crucial in various applications ranging from marketing and policy-making to personalized recommendations. The main objective is to learn optimal treatment allocations for a heterogeneous population. A primary line of…

Methodology · Statistics 2023-12-20 Preetam Nandy , Xiufan Yu , Wanjun Liu , Ye Tu , Kinjal Basu , Shaunak Chatterjee

A key task in clinical EEG interpretation is to classify a recording or session as normal or abnormal. In machine learning approaches to this task, recordings are typically divided into shorter windows for practical reasons, and these…

Machine Learning · Computer Science 2024-01-17 Yixuan Zhu , Luke J. W. Canham , David Western

Medical anomaly detection aims to identify abnormal findings using only normal training data, playing a crucial role in health screening and recognizing rare diseases. Reconstruction-based methods, particularly those utilizing autoencoders…

Machine Learning · Computer Science 2024-07-10 Yu Cai , Hao Chen , Kwang-Ting Cheng

It has been rightfully emphasized that the use of AI for clinical decision making could amplify health disparities. An algorithm may encode protected characteristics, and then use this information for making predictions due to undesirable…

Machine Learning · Computer Science 2022-07-22 Ben Glocker , Charles Jones , Melanie Bernhardt , Stefan Winzeck

The distribution of health care payments to insurance plans has substantial consequences for social policy. Risk adjustment formulas predict spending in health insurance markets in order to provide fair benefits and health care coverage for…

Applications · Statistics 2021-02-25 Anna Zink , Sherri Rose

Clinical predictive algorithms are increasingly being used to form the basis for optimal treatment policies--that is, to enable interventions to be targeted to the patients who will presumably benefit most. Despite taking advantage of…

Applications · Statistics 2020-07-21 Ben J. Marafino , Alejandro Schuler , Vincent X. Liu , Gabriel J. Escobar , Mike Baiocchi

Machine learning models for medical image analysis often suffer from poor performance on important subsets of a population that are not identified during training or testing. For example, overall performance of a cancer detection model may…

Machine Learning · Computer Science 2019-11-18 Luke Oakden-Rayner , Jared Dunnmon , Gustavo Carneiro , Christopher Ré

In many business applications, including online marketing and customer churn prevention, randomized controlled trials (RCT's) are conducted to investigate on the effect of specific treatment (coupon offers, advertisement mailings,...). Such…

Methodology · Statistics 2024-01-26 Björn Bokelmann , Stefan Lessmann

Recent advances in deep learning led to novel generative modeling techniques that achieve unprecedented quality in generated samples and performance in learning complex distributions in imaging data. These new models in medical image…

Computer Vision and Pattern Recognition · Computer Science 2018-06-15 Xiaoran Chen , Nick Pawlowski , Martin Rajchl , Ben Glocker , Ender Konukoglu

Machine learning methods are increasingly applied in medical imaging, yet many reported improvements lack statistical robustness: recent works have highlighted that small but significant performance gains are highly likely to be false…

Machine Learning · Computer Science 2025-11-05 Thomas Sanchez , Pedro M. Gordaliza , Meritxell Bach Cuadra

Predictive modeling in healthcare continues to be an active actuarial research topic as more insurance companies aim to maximize the potential of Machine Learning approaches to increase their productivity and efficiency. In this paper, the…

Machine Learning · Computer Science 2023-11-27 Ugochukwu Orji , Elochukwu Ukwandu

A major challenge in embedding or visualizing clinical patient data is the heterogeneity of variable types including continuous lab values, categorical diagnostic codes, as well as missing or incomplete data. In particular, in EHR data,…

Randomized experiments have been critical tools of decision making for decades. However, subjects can show significant heterogeneity in response to treatments in many important applications. Therefore it is not enough to simply know which…

Machine Learning · Computer Science 2017-09-13 Yan Zhao , Xiao Fang , David Simchi-Levi

Confounding pathology with normal anatomical variation remains a significant challenge in unsupervised medical-image anomaly detection, resulting in numerous false positives. To enhance integration of healthy variation, we augment the…

Quantitative Methods · Quantitative Biology 2026-03-09 P. Bilha Githinji , Xi Yuan , Ijaz Gul , Lian Zhang , Jinhao Xu , Zhenglin Chen , Peiwu Qin , Dongmei Yu

Given a large number of low-level heterogeneous categorical alerts from an anomaly detection system, how to characterize complex relationships between different alerts, filter out false positives, and deliver trustworthy rankings and…

Cryptography and Security · Computer Science 2018-02-15 Ying Lin , Zhengzhang Chen , Cheng Cao , Lu-an Tang , Kai Zhang , Zhichun Li , Haifeng Chen , Guofei Jiang

Anomaly detection in MRI is of high clinical value in imaging and diagnosis. Unsupervised methods for anomaly detection provide interesting formulations based on reconstruction or latent embedding, offering a way to observe properties…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Ayantika Das , Arun Palla , Keerthi Ram , Mohanasankar Sivaprakasam

Containment of epidemic outbreaks entails great societal and economic costs. Cost-effective containment strategies rely on efficiently identifying infected individuals, making the best possible use of the available testing resources.…

Populations and Evolution · Quantitative Biology 2020-12-01 Laura Natali , Saga Helgadottir , Onofrio M. Marago , Giovanni Volpe

Machine learning-based medical anomaly detection is an important problem that has been extensively studied. Numerous approaches have been proposed across various medical application domains and we observe several similarities across these…

Machine Learning · Computer Science 2021-04-14 Tharindu Fernando , Harshala Gammulle , Simon Denman , Sridha Sridharan , Clinton Fookes