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Graph Representation Learning (GRL) has experienced significant progress as a means to extract structural information in a meaningful way for subsequent learning tasks. Current approaches including shallow embeddings and Graph Neural…

Machine Learning · Computer Science 2020-06-19 Antonia Gogoglou , C. Bayan Bruss , Brian Nguyen , Reza Sarshogh , Keegan E. Hines

How to obtain informative representations of molecules is a crucial prerequisite in AI-driven drug design and discovery. Recent researches abstract molecules as graphs and employ Graph Neural Networks (GNNs) for molecular representation…

Biomolecules · Quantitative Biology 2020-10-30 Yu Rong , Yatao Bian , Tingyang Xu , Weiyang Xie , Ying Wei , Wenbing Huang , Junzhou Huang

Molecular machine learning (ML) has proven important for tackling various molecular problems, such as predicting molecular properties based on molecular descriptors or fingerprints. Since relatively recently, graph neural network (GNN)…

Machine Learning · Computer Science 2023-09-06 Alexander Kensert , Gert Desmet , Deirdre Cabooter

Self-supervised graph representation learning (SSGRL) is a representation learning paradigm used to reduce or avoid manual labeling. An essential part of SSGRL is graph data augmentation. Existing methods usually rely on heuristics commonly…

Machine Learning · Computer Science 2024-12-25 Ahmed E. Samy , Zekarias T. Kefatoa , Sarunas Girdzijauskasa

Unsupervised graph representation learning(GRL) aims to distill diverse graph information into task-agnostic embeddings without label supervision. Due to a lack of support from labels, recent representation learning methods usually adopt…

Machine Learning · Computer Science 2023-04-18 Bei Lin , You Li , Ning Gui , Zhuopeng Xu , Zhiwu Yu

We introduce a novel approach to graph-level representation learning, which is to embed an entire graph into a vector space where the embeddings of two graphs preserve their graph-graph proximity. Our approach, UGRAPHEMB, is a general…

Machine Learning · Computer Science 2019-06-04 Yunsheng Bai , Hao Ding , Yang Qiao , Agustin Marinovic , Ken Gu , Ting Chen , Yizhou Sun , Wei Wang

Graph self-supervised learning (GSSL) has emerged as a compelling framework for extracting informative representations from graph-structured data without extensive reliance on labeled inputs. In this study, we introduce Graph Interplay…

Machine Learning · Computer Science 2025-01-17 Xinjian Zhao , Wei Pang , Xiangru Jian , Yaoyao Xu , Chaolong Ying , Tianshu Yu

The search for new high-performance organic semiconducting molecules is challenging due to the vastness of the chemical space, machine learning methods, particularly deep learning models like graph neural networks (GNNs), have shown…

Chemical Physics · Physics 2021-12-06 Zaixi Zhang , Qi Liu , Shengyu Zhang , Chang-Yu Hsieh , Liang Shi , Chee-Kong Lee

Deep learning on graphs has attracted significant interests recently. However, most of the works have focused on (semi-) supervised learning, resulting in shortcomings including heavy label reliance, poor generalization, and weak…

Machine Learning · Computer Science 2022-05-05 Yixin Liu , Ming Jin , Shirui Pan , Chuan Zhou , Yu Zheng , Feng Xia , Philip S. Yu

Self-supervised heterogeneous graph learning (SHGL) has shown promising potential in diverse scenarios. However, while existing SHGL methods share a similar essential with clustering approaches, they encounter two significant limitations:…

Artificial Intelligence · Computer Science 2024-12-03 Yujie Mo , Zhihe Lu , Runpeng Yu , Xiaofeng Zhu , Xinchao Wang

Dual embodied-symbolic concept representations are the foundation for deep learning and symbolic AI integration. We discuss the use of dual embodied-symbolic concept representations for molecular graph representation learning, specifically…

Machine Learning · Computer Science 2022-05-16 Daniel T. Chang

Graph neural networks (GNNs) demonstrate great performance in compound property and activity prediction due to their capability to efficiently learn complex molecular graph structures. However, two main limitations persist including…

Biomolecules · Quantitative Biology 2023-10-10 Apakorn Kengkanna , Masahito Ohue

Self-supervised learning provides a promising path towards eliminating the need for costly label information in representation learning on graphs. However, to achieve state-of-the-art performance, methods often need large numbers of…

Self-supervised learning (SSL) has shown great promise in graph representation learning. However, most existing graph SSL methods are developed and evaluated under a single-dataset setting, leaving their cross-dataset transferability…

Machine Learning · Computer Science 2025-09-10 Yu Song , Zhigang Hua , Yan Xie , Jingzhe Liu , Bo Long , Hui Liu

Unsupervised node representation learning aims to obtain meaningful node embeddings without relying on node labels. To achieve this, graph convolution, which aggregates information from neighboring nodes, is commonly employed to encode node…

Machine Learning · Computer Science 2025-12-18 Sunwoo Kim , Soo Yong Lee , Kyungho Kim , Hyunjin Hwang , Jaemin Yoo , Kijung Shin

Subgraph classification is an emerging field in graph representation learning where the task is to classify a group of nodes (i.e., a subgraph) within a graph. Subgraph classification has applications such as predicting the cellular…

Machine Learning · Computer Science 2023-04-19 Shweta Ann Jacob , Paul Louis , Amirali Salehi-Abari

Generative graph self-supervised learning (SSL) aims to learn node representations by reconstructing the input graph data. However, most existing methods focus on unsupervised learning tasks only and very few work has shown its superiority…

Machine Learning · Computer Science 2023-02-08 Xiang Li , Tiandi Ye , Caihua Shan , Dongsheng Li , Ming Gao

Graph representation learning has emerged as a powerful tool for preserving graph topology when mapping nodes to vector representations, enabling various downstream tasks such as node classification and community detection. However, most…

Machine Learning · Computer Science 2025-03-21 Kaizhe Fan , Quanjun Li

Deep models trained in supervised mode have achieved remarkable success on a variety of tasks. When labeled samples are limited, self-supervised learning (SSL) is emerging as a new paradigm for making use of large amounts of unlabeled…

Machine Learning · Computer Science 2022-04-26 Yaochen Xie , Zhao Xu , Jingtun Zhang , Zhengyang Wang , Shuiwang Ji

Over the past few years, graph representation learning (GRL) has been a powerful strategy for analyzing graph-structured data. Recently, GRL methods have shown promising results by adopting self-supervised learning methods developed for…

Machine Learning · Computer Science 2022-09-05 Namkyeong Lee , Dongmin Hyun , Junseok Lee , Chanyoung Park