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In medical image segmentation, it is often necessary to collect opinions from multiple experts to make the final decision. This clinical routine helps to mitigate individual bias. But when data is multiply annotated, standard deep learning…

Image and Video Processing · Electrical Eng. & Systems 2022-12-02 Junde Wu , Huihui Fang , Yehui Yang , Yuanpei Liu , Jing Gao , Lixin Duan , Weihua Yang , Yanwu Xu

Compared to natural images, medical images usually show stronger visual patterns and therefore this adds flexibility and elasticity to resource-limited clinical applications by injecting proper priors into neural networks. In this paper, we…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Hang Zhang , Rongguang Wang , Jinwei Zhang , Dongdong Liu , Chao Li , Jiahao Li

A key feature of magnetic resonance (MR) imaging is its ability to manipulate how the intrinsic tissue parameters of the anatomy ultimately contribute to the contrast properties of the final, acquired image. This flexibility, however, can…

Computer Vision and Pattern Recognition · Computer Science 2018-11-20 Dzung L. Pham , Snehashis Roy

The consideration of predictive uncertainty in medical imaging with deep learning is of utmost importance. We apply estimation of both aleatoric and epistemic uncertainty by variational Bayesian inference with Monte Carlo dropout to…

Image and Video Processing · Electrical Eng. & Systems 2021-04-27 Max-Heinrich Laves , Sontje Ihler , Jacob F. Fast , Lüder A. Kahrs , Tobias Ortmaier

Echocardiography plays a fundamental role in the extraction of important clinical parameters (e.g. left ventricular volume and ejection fraction) required to determine the presence and severity of heart-related conditions. When deploying…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Thierry Judge , Olivier Bernard , Woo-Jin Cho Kim , Alberto Gomez , Arian Beqiri , Agisilaos Chartsias , Pierre-Marc Jodoin

Uncertainty in medical image segmentation is inherently non-uniform, with boundary regions exhibiting substantially higher ambiguity than interior areas. Conventional training treats all pixels equally, leading to unstable optimization…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Jinming Zhang , Youpeng Yang , Xi Yang , Haosen Shi , Yuyao Yan , Qiufeng Wang , Guangliang Cheng , Kaizhu Huang

Medical image segmentation is a fundamental and critical step in many clinical approaches. Semi-supervised learning has been widely applied to medical image segmentation tasks since it alleviates the heavy burden of acquiring…

Image and Video Processing · Electrical Eng. & Systems 2022-08-29 Yichi Zhang , Rushi Jiao , Qingcheng Liao , Dongyang Li , Jicong Zhang

Accurate and robust ultrasound image segmentation is critical for computer-aided diagnostic systems. Nevertheless, the inherent challenges of ultrasound imaging, such as blurry boundaries and speckle noise, often cause traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-01-03 Jiang Shang , Yuanmeng Wu , Xiaoxiang Han , Xi Chen , Qi Zhang

In recent years, machine learning has witnessed extensive adoption across various sectors, yet its application in medical image-based disease detection and diagnosis remains challenging due to distribution shifts in real-world data. In…

Machine Learning · Computer Science 2024-02-13 Masoumeh Javanbakhat , Md Tasnimul Hasan , Cristoph Lippert

The interpretation of medical images is a challenging task, often complicated by the presence of artifacts, occlusions, limited contrast and more. Most notable is the case of chest radiography, where there is a high inter-rater variability…

Ambiguous Medical Image Segmentation (AMIS) is significant to address the challenges of inherent uncertainties from image ambiguities, noise, and subjective annotations. Existing conditional variational autoencoder (cVAE)-based methods…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Xiangyu Li , Chenglin Wang , Qiantong Shen , Fanding Li , Wei Wang , Kuanquan Wang , Yi Shen , Baochun Zhao , Gongning Luo

In this paper we address the uncertainty issues involved in the low-level vision task of image segmentation. Researchers in computer vision have worked extensively on this problem, in which the goal is to partition (or segment) an image…

Artificial Intelligence · Computer Science 2013-03-08 Steven M. LaValle , Seth A. Hutchinson

Ultrasound (US) image segmentation embraced its significant improvement in deep learning era. However, the lack of sharp boundaries in US images still remains an inherent challenge for segmentation. Previous methods often resort to global…

Image and Video Processing · Electrical Eng. & Systems 2020-10-13 Haoming Li , Xin Yang , Jiamin Liang , Wenlong Shi , Chaoyu Chen , Haoran Dou , Rui Li , Rui Gao , Guangquan Zhou , Jinghui Fang , Xiaowen Liang , Ruobing Huang , Alejandro Frangi , Zhiyi Chen , Dong Ni

Deep learning models for medical imaging often exhibit overconfidence, creating safety risks in ambiguous diagnostic scenarios. While Conformal Prediction (CP) provides distribution-free statistical guarantees, standard methods such as…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 One Octadion , Novanto Yudistira , Lailil Muflikhah

Medical images are often used to detect and characterize pathology and disease; however, automatically identifying and segmenting pathology in medical images is challenging because the appearance of pathology across diseases varies widely.…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Jacob C. Reinhold , Yufan He , Shizhong Han , Yunqiang Chen , Dashan Gao , Junghoon Lee , Jerry L. Prince , Aaron Carass

We address the selection and evaluation of uncertain segmentation methods in medical imaging and present two case studies: prostate segmentation, illustrating that for minimal annotator variation simple deterministic models can suffice, and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-24 Kilian Zepf , Jes Frellsen , Aasa Feragen

In computational histopathology algorithms now outperform humans on a range of tasks, but to date none are employed for automated diagnoses in the clinic. Before algorithms can be involved in such high-stakes decisions they need to "know…

Computer Vision and Pattern Recognition · Computer Science 2022-10-19 Lea Goetz

Image segmentation enables to extract quantitative measures from scans that can serve as imaging biomarkers for diseases. However, segmentation quality can vary substantially across scans, and therefore yield unfaithful estimates in the…

Image and Video Processing · Electrical Eng. & Systems 2020-11-03 J. Senapati , A. Guha Roy , S. Pölsterl , D. Gutmann , S. Gatidis , C. Schlett , A. Peters , F. Bamberg , C. Wachinger

We evaluate two different methods for the integration of prediction uncertainty into diagnostic image classifiers to increase patient safety in deep learning. In the first method, Monte Carlo sampling is applied with dropout at test time to…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Max-Heinrich Laves , Sontje Ihler , Tobias Ortmaier

Existing deep-learning based tomographic image reconstruction methods do not provide accurate estimates of reconstruction uncertainty, hindering their real-world deployment. This paper develops a method, termed as the linearised deep image…

Image and Video Processing · Electrical Eng. & Systems 2022-11-07 Javier Antorán , Riccardo Barbano , Johannes Leuschner , José Miguel Hernández-Lobato , Bangti Jin