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We present a brief history of the field of interpretable machine learning (IML), give an overview of state-of-the-art interpretation methods, and discuss challenges. Research in IML has boomed in recent years. As young as the field is, it…

Machine Learning · Statistics 2022-01-24 Christoph Molnar , Giuseppe Casalicchio , Bernd Bischl

High-throughput technologies such as next generation sequencing allow biologists to observe cell function with unprecedented resolution, but the resulting datasets are too large and complicated for humans to understand without the aid of…

Applications · Statistics 2021-10-08 David S. Watson

Machine learning (ML) has seen significant growth in both popularity and importance. The high prediction accuracy of ML models is often achieved through complex black-box architectures that are difficult to interpret. This interpretability…

Machine Learning · Statistics 2024-07-29 David Köhler , David Rügamer , Matthias Schmid

In machine learning (ML), it is in general challenging to provide a detailed explanation on how a trained model arrives at its prediction. Thus, usually we are left with a black-box, which from a scientific standpoint is not satisfactory.…

Materials Science · Physics 2021-04-22 Luca M. Ghiringhelli

While the uptake of data-driven approaches for materials science and chemistry is at an exciting, early stage, to realise the true potential of machine learning models for successful scientific discovery, they must have qualities beyond…

Materials Science · Physics 2022-06-28 Felipe Oviedo , Juan Lavista Ferres , Tonio Buonassisi , Keith Butler

Recent efforts in Machine Learning (ML) interpretability have focused on creating methods for explaining black-box ML models. However, these methods rely on the assumption that simple approximations, such as linear models or decision-trees,…

Machine Learning · Computer Science 2019-06-13 Owen Lahav , Nicholas Mastronarde , Mihaela van der Schaar

Interpretable Machine Learning (IML) has become increasingly important in many real-world applications, such as autonomous cars and medical diagnosis, where explanations are significantly preferred to help people better understand how…

Machine Learning · Computer Science 2019-08-19 Fan Yang , Mengnan Du , Xia Hu

Interpretable machine learning tackles the important problem that humans cannot understand the behaviors of complex machine learning models and how these models arrive at a particular decision. Although many approaches have been proposed, a…

Machine Learning · Computer Science 2019-05-21 Mengnan Du , Ninghao Liu , Xia Hu

Through extensive experience developing and explaining machine learning (ML) applications for real-world domains, we have learned that ML models are only as interpretable as their features. Even simple, highly interpretable model types such…

Machine Learning · Computer Science 2022-02-25 Alexandra Zytek , Ignacio Arnaldo , Dongyu Liu , Laure Berti-Equille , Kalyan Veeramachaneni

Inherently interpretable machine learning (IML) models offer valuable support for clinical decision-making but face challenges when features contain missing values. Traditional approaches, such as imputation or discarding incomplete…

Machine Learning · Computer Science 2025-02-12 Lena Stempfle , Arthur James , Julie Josse , Tobias Gauss , Fredrik D. Johansson

The potential of Machine Learning Control (MLC) in HVAC systems is hindered by its opaque nature and inference mechanisms, which is challenging for users and modelers to fully comprehend, ultimately leading to a lack of trust in MLC-based…

Artificial Intelligence · Computer Science 2024-11-18 Liang Zhang , Zhelun Chen

Though neural networks trained on large datasets have been successfully used to describe and predict many physical phenomena, there is a sense among scientists that, unlike traditional scientific models comprising simple mathematical…

Machine Learning · Computer Science 2026-04-23 Conor Rowan , Alireza Doostan

Interpretable machine learning (IML) becomes increasingly important in highly regulated industry sectors related to the health and safety or fundamental rights of human beings. In general, the inherently IML models should be adopted because…

Machine Learning · Computer Science 2021-11-03 Agus Sudjianto , Aijun Zhang

New technologies have led to vast troves of large and complex datasets across many scientific domains and industries. People routinely use machine learning techniques to not only process, visualize, and make predictions from this big data,…

Machine Learning · Statistics 2023-08-04 Genevera I. Allen , Luqin Gan , Lili Zheng

Despite increasing interest in the field of Interpretable Machine Learning (IML), a significant gap persists between the technical objectives targeted by researchers' methods and the high-level goals of consumers' use cases. In this work,…

Machine Learning · Computer Science 2021-07-30 Valerie Chen , Jeffrey Li , Joon Sik Kim , Gregory Plumb , Ameet Talwalkar

Interpretability provides a means for humans to verify aspects of machine learning (ML) models and empower human+ML teaming in situations where the task cannot be fully automated. Different contexts require explanations with different…

Machine Learning · Computer Science 2024-07-15 Zixi Chen , Varshini Subhash , Marton Havasi , Weiwei Pan , Finale Doshi-Velez

This paper presents a systematic literature review (SLR) on the explainability and interpretability of machine learning (ML) models within the context of predictive process mining, using the PRISMA framework. Given the rapid advancement of…

Machine Learning · Computer Science 2024-01-01 Nijat Mehdiyev , Maxim Majlatow , Peter Fettke

Machine-learning models have demonstrated great success in learning complex patterns that enable them to make predictions about unobserved data. In addition to using models for prediction, the ability to interpret what a model has learned…

Machine Learning · Statistics 2019-11-15 W. James Murdoch , Chandan Singh , Karl Kumbier , Reza Abbasi-Asl , Bin Yu

Machine learning (ML) has emerged as a powerful tool for tackling complex regression and classification tasks, yet its success often hinges on the quality of training data. This study introduces an ML paradigm inspired by domain knowledge…

Machine Learning · Computer Science 2025-01-10 Mohsen Rashki

Artificial intelligence (AI) provides many opportunities to improve private and public life. Discovering patterns and structures in large troves of data in an automated manner is a core component of data science, and currently drives…

Machine Learning · Computer Science 2020-09-25 Vaishak Belle , Ioannis Papantonis
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