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Nutrient gradients and limitations play a pivotal role in the life of all microbes, both in their natural habitat as well as in artificial, microfluidic systems. Spatial concentration gradients of nutrients in densely packed cell…

We study the evolution of dynamic fluctuations averaged over different space lengths and time scales to characterize spatially and temporally heterogeneous behavior of TIP4P/2005 water in liquid and supercooled states. Analysing a million…

Communication between cells is realized by exchange of biochemical substances. Due to internal organization of living systems and variability of external parameters, the exchange is heavily influenced by perturbations of various parameters…

Chaotic Dynamics · Physics 2015-05-19 Dragutin T. Mihailovic , Igor Balaz

Biological populations are subject to fluctuating environmental conditions. Different adaptive strategies can allow them to cope with these fluctuations: specialization to one particular environmental condition, adoption of a generalist…

Populations and Evolution · Quantitative Biology 2017-09-27 Andreas Mayer , Thierry Mora , Olivier Rivoire , Aleksandra M. Walczak

In Escherichia coli the response to DNA damage shows strong cell-to-cell-heterogenity. This results in a random delay in cell division and asymmetrical binary fission of single cells, which can compromise the size homeostasis of the…

Quantitative Methods · Quantitative Biology 2024-09-27 Ignacio Madrid Canales , James Broughton , Sylvie Méléard , Meriem El Karoui

We study how changes in population size and fluctuating environmental conditions influence the establishment of seed banks in plants. Our model is a modification of the Wright-Fisher model with seed bank, introduced by Kaj, Krone and…

Probability · Mathematics 2026-02-05 Alison Etheridge , João Luiz de Oliveira Madeira

Bacterial processes ranging from gene expression to motility and biofilm formation are constantly challenged by internal and external noise. While the importance of stochastic fluctuations has been appreciated for chemotaxis, it is…

Biological Physics · Physics 2011-07-13 Knut Drescher , Jörn Dunkel , Luis H. Cisneros , Sujoy Ganguly , Raymond E. Goldstein

A recent burst of dynamic single-cell growth-division data makes it possible to characterize the stochastic dynamics of cell division control in bacteria. Different modeling frameworks were used to infer specific mechanisms from such data,…

Cell Behavior · Quantitative Biology 2017-03-22 Jacopo Grilli , Matteo Osella , Andrew S. Kennard , Marco Cosentino Lagomarsino

The spatiotemporal coordination and regulation of cell proliferation is fundamental in many aspects of development and tissue maintenance. Cells have the ability to adapt their division rates in response to mechanical constraints, yet we do…

Quantitative Methods · Quantitative Biology 2024-04-25 Carles Falcó , Daniel J. Cohen , José A. Carrillo , Ruth E. Baker

We study the effect of discreteness on various models for patterning in bacterial colonies. In a bacterial colony with branching pattern, there are discrete entities - bacteria - which are only two orders of magnitude smaller than the…

Disordered Systems and Neural Networks · Physics 2007-05-23 Inon Cohen , Ido Golding , Yonathan Kozlovsky , Eshel Ben-Jacob

Bacteria can form a great variety of spatially heterogeneous cell density patterns, ranging from simple concentric rings to dynamical spiral waves appearing in growing colonies. These pattern formation phenomena are important as they…

Populations and Evolution · Quantitative Biology 2025-01-17 John S. Chuang , Riccardo Rao , Stanislas Leibler

In this work, we study a model of the chemostat where the species are present in two forms, isolated bacteria and under an aggregated form like attached bacteria or bacteria in flocks. We show that our general model contains a lot of models…

Dynamical Systems · Mathematics 2012-03-13 Radhoaune Fekih-Salem , Jérôme Harmand , Claude Lobry , Alain Rapaport , Tewfik Sari

Biological growth is often driven by mechanical cues, such as changes in external pressure or tensile loading. Moreover, it is well known that many living tissues actively maintain a preferred level of mechanical internal stress, called the…

Biological Physics · Physics 2018-04-24 Alexander Erlich , Derek E. Moulton , Alain Goriely

The exchange of information between an open quantum system and its environment allows us to discriminate among different kinds of dynamics, in particular detecting memory effects to characterize non-Markovianity. Here, we investigate the…

Quantum Physics · Physics 2021-04-28 Andrea Smirne , Nina Megier , Bassano Vacchini

Many diatoms follow a size diminuation - size restoration cycle in their vegetative phase, leading to daughter cells that differ in size. For the diatom Seminavis robusta, we investigated by cell tracking over several generations whether…

Quantitative Methods · Quantitative Biology 2026-03-19 Jonas Ziebarth , Thomas Fuhrmann-Lieker

Multicellular organisms comprise a diverse collection of stable tissues built from different cell types. It remains unclear how large numbers of interacting cells can precisely coordinate their gene expression during tissue…

Biological Physics · Physics 2022-10-31 Matthew Smart , Anton Zilman

Motile cells often explore natural environments characterized by a high degree of structural complexity. Moreover cell motility is also intrinsically noisy due to spontaneous random reorientation and speed fluctuations. This interplay of…

We introduce various models for cellulose bio-degradation by micro-organisms. Those models rely on complex chemical mechanisms, involve the structure of the cellulose chains and are allowed to depend on the phenotypical traits of the…

Dynamical Systems · Mathematics 2020-11-09 Pierre-Emmanuel Jabin , Alexey Miroshnikov , Robin Young

This paper presents an interesting experimental example of voter-model statistics in biology. In recent work on mouse tail-skin, where proliferating cells are confined to a two-dimensional layer, we showed that cells proliferate and…

Biological Physics · Physics 2009-11-13 Allon M. Klein , David P. Doupe , Philip H. Jones , Benjamin D. Simons

We consider the effects of long-range temporal correlations in many-particle systems, focusing particularly on fluctuations about the typical behaviour. For a specific class of memory dependence we discuss the modification of the large…

Statistical Mechanics · Physics 2015-12-24 Rosemary J. Harris