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Undirected graphical models are a key component in the analysis of complex observational data in a large variety of disciplines. In many of these applications one is interested in estimating the undirected graphical model underlying a…

Applications · Statistics 2015-10-21 Jonas M. B. Haslbeck , Lourens J. Waldorp

The assessment of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) associated with brain changes remains a challenging task. Recent studies have demonstrated that combination of multi-modality imaging techniques can better…

Machine Learning · Computer Science 2022-09-26 Jun Yu , Zhaoming Kong , Liang Zhan , Li Shen , Lifang He

Detection of Alzheimer's Disease (AD) from neuroimaging data such as MRI through machine learning has been a subject of intense research in recent years. Recent success of deep learning in computer vision has progressed such research…

Computer Vision and Pattern Recognition · Computer Science 2019-06-05 Naimul Mefraz Khan , Marcia Hon , Nabila Abraham

Computer-aided early diagnosis of Alzheimer's disease (AD) and its prodromal form mild cognitive impairment (MCI) based on structure Magnetic Resonance Imaging (sMRI) has provided a cost-effective and objective way for early prevention and…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Xin Zhang , Liangxiu Han , Wenyong Zhu , Liang Sun , Daoqiang Zhang

Conventionally, evaluation for the diagnosis of Autism spectrum disorder is done by a trained specialist through questionnaire-based formal assessments and by observation of behavioral cues under various settings to capture the early…

Computer Vision and Pattern Recognition · Computer Science 2023-11-28 Vaibhavi Lokegaonkar , Vijay Jaisankar , Pon Deepika , Madhav Rao , T K Srikanth , Sarbani Mallick , Manjit Sodhi

Caregivers of individuals with autism spectrum disorder (ASD) often find the 77-item Autism Treatment Evaluation Checklist (ATEC) burdensome, limiting its use for routine monitoring. This study introduces a generalizable machine learning…

Applications · Statistics 2025-11-03 Audrey Dong , Claire Xu , Samuel R. Guo , Kevin Yang , Xue-Jun Kong

Currently, the diagnosis of Alzheimer's disease is a complex and error-prone process. Improving this diagnosis could allow earlier detection of the disease and improve the quality of life of patients and their families. For this work, we…

Image and Video Processing · Electrical Eng. & Systems 2022-10-18 Ángel de la Vega Jiménez

Autism Spectrum Disorders are associated with atypical movements, of which stereotypical motor movements (SMMs) interfere with learning and social interaction. The automatic SMM detection using inertial measurement units (IMU) remains…

Computer Vision and Pattern Recognition · Computer Science 2017-09-19 Nastaran Mohammadian Rad , Seyed Mostafa Kia , Calogero Zarbo , Twan van Laarhoven , Giuseppe Jurman , Paola Venuti , Elena Marchiori , Cesare Furlanello

Autism Spectrum Disorder (ASD) is neurodevelopmental condition characterized by social interaction and communication difficulties, along with narrow and repetitive interests. Being an spectrum disorder, ASD affects individuals with a large…

Software Engineering · Computer Science 2018-05-10 Roberto E. Lopez-Herrejon , Gerardo Herrera , Javier Sevilla

Deep learning models for MRI classification face two recurring problems: they are typically limited by low sample size, and are abstracted by their own complexity (the "black box problem"). In this paper, we train a convolutional neural…

Quantitative Methods · Quantitative Biology 2020-05-28 Matthew Leming , Juan Manuel Górriz , John Suckling

The application of deep learning to build accurate predictive models from functional neuroimaging data is often hindered by limited dataset sizes. Though data augmentation can help mitigate such training obstacles, most data augmentation…

Machine Learning · Computer Science 2019-10-21 Kevin P. Nguyen , Cherise Chin Fatt , Alex Treacher , Cooper Mellema , Madhukar H. Trivedi , Albert Montillo

There has been increasing interests in learning resting-state brain functional connectivity of autism disorders using functional magnetic resonance imaging (fMRI) data. The data in a standard brain template consist of over 200,000 voxel…

Methodology · Statistics 2016-03-22 Jichun Xie , Jian Kang

The insufficient supervision limit the performance of the deep supervised models for brain disease diagnosis. It is important to develop a learning framework that can capture more information in limited data and insufficient supervision. To…

Neurons and Cognition · Quantitative Biology 2024-10-10 Wenjing Gao , Yuanyuan Yang , Jianrui Wei , Xuntao Yin , Xinhan Di

Machine learning (ML) has shown great promise for revolutionizing a number of areas, including healthcare. However, it is also facing a reproducibility crisis, especially in medicine. ML models that are carefully constructed from and…

Machine Learning · Computer Science 2024-09-16 Rongguang Wang , Guray Erus , Pratik Chaudhari , Christos Davatzikos

In this work we show that the classification performance of high-dimensional structural MRI data with only a small set of training examples is improved by the usage of dimension reduction methods. We assessed two different dimension…

Machine Learning · Computer Science 2015-05-27 Andreas Grünauer , Markus Vincze

Objectives: The objectives of this narrative review are to summarize the current state of AI applications in neuroimaging for early Alzheimer's disease (AD) prediction and to highlight the potential of AI techniques in improving early AD…

Machine Learning · Computer Science 2024-06-27 Thorsten Rudroff , Oona Rainio , Riku Klén

Advances in machine learning and contactless sensors have enabled the understanding complex human behaviors in a healthcare setting. In particular, several deep learning systems have been introduced to enable comprehensive analysis of…

Computer Vision and Pattern Recognition · Computer Science 2024-03-06 Pengbo Wei , David Ahmedt-Aristizabal , Harshala Gammulle , Simon Denman , Mohammad Ali Armin

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition associated with difficulties with social interactions, communication, and restricted or repetitive behaviors. To characterize ASD, investigators often use functional…

Methodology · Statistics 2026-05-12 Jialu Ran , Sarah Shultz , Benjamin B. Risk , David Benkeser

This study is based on the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset and aims to explore early detection and disease progression in Alzheimer's disease (AD). We employ innovative data preprocessing strategies, including the…

Machine Learning · Computer Science 2024-02-14 Mingyang Li , Hongyu Liu , Yixuan Li , Zejun Wang , Yuan Yuan , Honglin Dai

Supervised deep learning techniques show promise in medical image analysis. However, they require comprehensive annotated data sets, which poses challenges, particularly for rare diseases. Consequently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Finn Behrendt , Debayan Bhattacharya , Lennart Maack , Julia Krüger , Roland Opfer , Robin Mieling , Alexander Schlaefer