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Accurate automatic medical image segmentation relies on high-quality, dense annotations, which are costly and time-consuming. Weakly supervised learning provides a more efficient alternative by leveraging sparse and coarse annotations…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Dongdong Meng , Sheng Li , Hao Wu , Suqing Tian , Wenjun Ma , Guoping Wang , Xueqing Yan

Accurate cell segmentation in pathology images typically requires dense pixel-wise annotations, which are costly and time-consuming to obtain. This challenge is especially important for emerging biological imaging modalities and multiplexed…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Gunjan Shrivastava , Saad Nadeem

Deep learning methods for classifying medical images have demonstrated impressive accuracy in a wide range of tasks but often these models are hard to interpret, limiting their applicability in clinical practice. In this work we introduce a…

Image and Video Processing · Electrical Eng. & Systems 2019-08-13 James R. Clough , Ilkay Oksuz , Esther Puyol-Anton , Bram Ruijsink , Andrew P. King , Julia A. Schnabel

In this paper, we study weakly-supervised laparoscopic image segmentation with sparse annotations. We introduce a novel Bayesian deep learning approach designed to enhance both the accuracy and interpretability of the model's segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Zhou Zheng , Yuichiro Hayashi , Masahiro Oda , Takayuki Kitasaka , Kensaku Mori

Histopathological analysis is crucial in artery characterization for coronary artery disease (CAD). However, histology requires an invasive and time-consuming process. In this paper, we propose to generate virtual histology staining using…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Xueshen Li , Hongshan Liu , Xiaoyu Song , Brigitta C. Brott , Silvio H. Litovsky , Yu Gan

The choroid provides oxygen and nourishment to the outer retina thus is related to the pathology of various ocular diseases. Optical coherence tomography (OCT) is advantageous in visualizing and quantifying the choroid in vivo. (1) The…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Huihong Zhang , Jianlong Yang , Kang Zhou , Fei Li , Yan Hu , Yitian Zhao , Ce Zheng , Xiulan Zhang , Jiang Liu

Optical coherence tomography angiography (OCTA) is a novel noninvasive imaging modality for visualization of retinal blood flow in the human retina. Using specific OCTA imaging biomarkers for the identification of pathologies, automated…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Anna Breger , Felix Goldbach , Bianca S. Gerendas , Ursula Schmidt-Erfurth , Martin Ehler

Cardiovascular diseases (CVD) are the leading cause of death globally. Non-invasive, cost-effective imaging techniques play a crucial role in early detection and prevention of CVD. Optical coherence tomography (OCT) has gained recognition…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Cynthia Maldonado-Garcia , Rodrigo Bonazzola , Enzo Ferrante , Thomas H Julian , Panagiotis I Sergouniotis , Nishant Ravikumara , Alejandro F Frangi

Inpainting shadowed regions cast by superficial blood vessels in retinal optical coherence tomography (OCT) images is critical for accurate and robust machine analysis and clinical diagnosis. Traditional sequence-based approaches such as…

Computer Vision and Pattern Recognition · Computer Science 2022-02-24 Yaoqi Tang , Yufan Li , Hongshan Liu , Jiaxuan Li , Peiyao Jin , Yu Gan , Yuye Ling , Yikai Su

Semi-supervised learning (SSL) has become a promising solution to alleviate the annotation burden of deep learning-based medical image segmentation models. While recent advances in foundation model-driven SSL have pushed the boundary to…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Yichi Zhang , Le Xue , Bichun Xu , Judong Luo , Zhigang Wu , Yu Fu , Zixin Hu , Yuan Cheng , Yuan Qi

The segmentation of the mitral valve annulus and leaflets specifies a crucial first step to establish a machine learning pipeline that can support physicians in performing multiple tasks, e.g.\ diagnosis of mitral valve diseases, surgical…

Image and Video Processing · Electrical Eng. & Systems 2020-08-14 Luca Corinzia , Fabian Laumer , Alessandro Candreva , Maurizio Taramasso , Francesco Maisano , Joachim M. Buhmann

Versatile medical image segmentation (VMIS) targets the segmentation of multiple classes, while obtaining full annotations for all classes is often impractical due to the time and labor required. Leveraging partially labeled datasets (PLDs)…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Shengqian Zhu , Jiafei Wu , Xiaogang Xu , Chengrong Yu , Ying Song , Zhang Yi , Guangjun Li , Junjie Hu

Optical Coherence Tomography Angiography (OCTA) is a non-invasive imaging technique that provides high-resolution cross-sectional images of the retina, which are useful for diagnosing and monitoring various retinal diseases. However, manual…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Can Koz , Onat Dalmaz , Mertay Dayanc

The success of deep convolutional neural networks is partially attributed to the massive amount of annotated training data. However, in practice, medical data annotations are usually expensive and time-consuming to be obtained. Considering…

Image and Video Processing · Electrical Eng. & Systems 2020-10-06 Kang Li , Lequan Yu , Shujun Wang , Pheng-Ann Heng

Recently deep neural networks, which require a large amount of annotated samples, have been widely applied in nuclei instance segmentation of H\&E stained pathology images. However, it is inefficient and unnecessary to label all pixels for…

Computer Vision and Pattern Recognition · Computer Science 2022-12-21 Wei Lou , Haofeng Li , Guanbin Li , Xiaoguang Han , Xiang Wan

Convolutional neural networks (CNN) have demonstrated their ability to segment 2D cardiac ultrasound images. However, despite recent successes according to which the intra-observer variability on end-diastole and end-systole images has been…

Image and Video Processing · Electrical Eng. & Systems 2022-05-09 Nathan Painchaud , Nicolas Duchateau , Olivier Bernard , Pierre-Marc Jodoin

Coronary artery disease (CAD) is the leading causes of death around the world. One of the most common imaging methods for diagnosing this disease is X-ray angiography. Diagnosing using these images is usually challenging due to non-uniform…

Computer Vision and Pattern Recognition · Computer Science 2017-09-11 Hamid R. Fazlali , Nader Karimi , S. M. Reza Soroushmehr , Shahram Shirani , Brahmajee. K. Nallamothu , Kevin R. Ward , Shadrokh Samavi , Kayvan Najarian

The absence of large scale datasets with pixel-level supervisions is a significant obstacle for the training of deep convolutional networks for scene text segmentation. For this reason, synthetic data generation is normally employed to…

Computer Vision and Pattern Recognition · Computer Science 2019-09-25 Simone Bonechi , Paolo Andreini , Monica Bianchini , Franco Scarselli

Optical coherence tomography angiography (OCTA) is a non-invasive imaging technique widely used to study vascular structures and micro-circulation dynamics in the retina and choroid. OCTA has been widely used in clinics for diagnosing…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Kejie Chen , Guanbing Gao , Xiaochun Yang , Wenbo Wang , Jing Na

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu