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Measuring the mechanical response of liquid interfaces without direct contact remains a major experimental challenge, particularly in liquid-liquid systems where no solid reference exists. Here, we develop a frequency-modulation atomic…

Soft Condensed Matter · Physics 2026-05-29 Lucie Corral , Christian Curtil , Medhi Lagaize , Marc Leonetti , Hubert R. Klein

Atomic Force Microscopy (AFM) allows to reconstruct the topography of surface with a resolution in the nanometer range. The exceptional resolution attainable with the AFM makes this instrument a key tool in nanoscience and technology. The…

Atomic force microscopy (AFM) is widely used to measure surface topography of solid, soft, and living matter at the nanoscale. Moreover, by mapping forces as a function of distance to the surface, AFM can provide a wealth of information…

Shape effects in magnetic particles are widely studied, because of the ability of the shape and the size to control the parameters of a sample during its production. Experiments with nano-sized samples show that the shape can affect also…

Mesoscale and Nanoscale Physics · Physics 2013-06-19 Svitlana V. Kondovych , Helen V. Gomonay , Vadim M. Loktev

Atomic force microscopy (AFM) is a versatile nanoscale imaging technique. Since its spatiotemporal resolution is fundamentally limited by the minimum detectable force (MDF) arising from system noise, a deep understanding of MDF is essential…

Applied Physics · Physics 2026-01-16 Kenichi Umeda , Noriyuki Kodera

Structural and mechanical differences between cancerous and healthy tissue give rise to variations in macroscopic properties such as visual appearance and elastic modulus that show promise as signatures for early cancer detection. Atomic…

Atomic force microscopy (AFM or SPM) imaging is one of the best matches with machine learning (ML) analysis among microscopy techniques. The digital format of AFM images allows for direct utilization in ML algorithms without the need for…

Biological Physics · Physics 2025-01-07 Igor Sokolov

The functionalization of an Atomic Force Microscope (AFM) cantilever with a colloidal bead is a widely used technique when the geometry between the probe and the sample must be controlled, particularly in force spectroscopy. But some…

Mesoscale and Nanoscale Physics · Physics 2013-05-09 Justine Laurent , Audrey Steinberger , Ludovic Bellon

While magnetic nanoparticles suspended in Newtonian solvents (ferrofluids) have been intensively studied in recent years, the effects of viscoelasticity of the surrounding medium on the nanoparticle dynamics are much less understood. Here…

Soft Condensed Matter · Physics 2018-04-18 Patrick Ilg , Apostolos E. A. S. Evangelopoulos

Measurements with an atomic force microscope (AFM) offer a direct way to probe elastic properties of lipid bilayer membranes locally: provided the underlying stress-strain relation is known, material parameters such as surface tension or…

Soft Condensed Matter · Physics 2007-05-23 Davood Norouzi , Martin Michael Mueller , Markus Deserno

AFM is a technique widely applied in the nanoscale characterisation of polymers and their surface properties. With nano-FTIR and IR-sSNOM imaging an optical dimension is added to this technique that allows for straightforward high…

Applied Physics · Physics 2019-06-26 Michaela Meyns , Sebastian Primpke , Gunnar Gerdts

We have developed a new technique to measure viscoelasticity in soft materials such as polymer solutions, by monitoring thermal fluctuations of embedded probe particles using laser interferometry in a microscope. Interferometry allows us to…

Soft Condensed Matter · Physics 2009-10-30 B. Schnurr , F. Gittes , F. C. MacKintosh , C. F. Schmidt

Effective medical simulators necessitate realistic haptic rendering of biological tissues that exhibit viscoelastic material properties, such as creep and stress relaxation. Fractional-order models provide an effective means of describing…

Systems and Control · Electrical Eng. & Systems 2026-05-20 Harun Tolasa , Gorkem Gemalmaz , Volkan Patoglu

We propose a statistical model for static and sliding friction between rough surfaces. Approximating the contact between rough surfaces by the contact of an ensemble of one-dimensional viscoelastic elements with a rough rigid surface, we…

Soft Condensed Matter · Physics 2015-06-19 Srivatsan Hulikal , Kaushik Bhattacharya , Nadia Lapusta

In the context of direct detection sensors with compact dimensions, we investigate the gravimetric sensitivity of High-overtone Bulk Acoustic Resonators, through modeling of their acoustic characteristics and experiment. The high frequency…

Instrumentation and Detectors · Physics 2015-09-30 D. Rabus , J. -M Friedt , S. Ballandras , T. Baron , E. Lebrasseur , E. Carry

Mechanical nonlinearities dominate the motion of nanoresonators already at relatively small oscillation amplitudes. Although single and coupled two-degrees-of-freedom models have been used to account for experimentally observed nonlinear…

Mesoscale and Nanoscale Physics · Physics 2023-04-05 Ata Keşkekler , Vincent Bos , Alejandro M. Aragón , Peter G. Steeneken , Farbod Alijani

Traumatic axonal injury occurs when loads experienced on the tissue-scale are transferred to the individual axons. Mechanical characterization of axon deformation especially under dynamic loads however is extremely difficult owing to their…

Applied Physics · Physics 2023-04-14 Parameshwaran Pasupathy , John G Georgiadis , Assimina A Pelegri

Clinically, palpation is one of the important diagnostic methods to assess tumor malignancy. In laboratory research, it is well accepted that the bulk stiffness of the tumor and the surrounding tissue is closely correlated with the…

Soft Condensed Matter · Physics 2025-09-23 Mrinal Pandey , Bangguo Zhu , Kaitlyn Roach , Young Joon Suh , Jeffrey E Segall , Chung-Yuen Hui , Mingming Wu

Atomic force spectroscopy and microscopy (AFM) are invaluable tools to characterize nanostructures and biological systems. Most experiments, including state-of-the-art images of molecular bonds, are achieved by driving probes at their…

Surface wettability has a huge influence on its functional properties. For example, to minimize smudging, surfaces should be able to repel oil droplets. To quantify surface wettability, the most common approach is to measure the contact…

Soft Condensed Matter · Physics 2020-04-09 Dan Daniel , Yunita Florida , Chee Leng Lay , Xue Qi Koh , Anqi Sng , Nikodem Tomczak