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In this paper, we study the phase transition behavior emerging from the interactions among multiple agents in the presence of noise. We propose a simple discrete-time model in which a group of non-mobile agents form either a fixed connected…

Optimization and Control · Mathematics 2008-10-21 Jialing Liu , Vikas Yadav , Hullas Sehgal , Joshua M. Olson , Haifeng Liu , Nicola Elia

The denoising process of diffusion models can be interpreted as an approximate projection of noisy samples onto the data manifold. Moreover, the noise level in these samples approximates their distance to the underlying manifold. Building…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Abulikemu Abuduweili , Chenyang Yuan , Changliu Liu , Frank Permenter

Recent advances in high-resolution experimental methods have highlighted the significance of cell signal pathway crosstalk and localised signalling activity in the development and disease of numerous biological systems. The investigation of…

Dynamical Systems · Mathematics 2022-09-19 Joshua W. Moore , Trevor C. Dale , Thomas E. Woolley

Biological cells estimate concentration gradients of signaling molecules with a precision that is limited not only by sensing noise, but additionally by the cell's own stochastic motion. We ask for the theoretical limits of gradient…

Biological Physics · Physics 2021-05-26 Maja Novak , Benjamin M. Friedrich

The modeling of finite-extent semiconductor nanostructures that are embedded in a host material requires the numerical treatment of the boundary in a finite simulation domain. For the study of a self-assembled InAs dot embedded in GaAs,…

Materials Science · Physics 2009-11-10 Seungwon Lee , Fabiano Oyafuso , Paul von Allmen , Gerhard Klimeck

A new approach to the solution of boundary value problems within the so-called fictitious domain methods philosophy is proposed which avoids well known shortcomings of other fictitious domain methods, including the need to generate…

Numerical Analysis · Mathematics 2019-01-17 Daniel Agress , Patrick Guidotti

Experimental evidence lends support to the conjecture that the ability of chains of cells to sense the gradient of an external chemical concentration could rely on cell-to-cell communication. This is the basis for the gradient sensing…

Quantitative Methods · Quantitative Biology 2021-02-24 Dallas Foster , Collin Victor , Brian Frost , Juan M. Restrepo

Considerable advancements have been achieved in SLAM methods tailored for structured environments, yet their robustness under challenging corner cases remains a critical limitation. Although multi-sensor fusion approaches integrating…

Robotics · Computer Science 2025-07-14 Deteng Zhang , Junjie Zhang , Yan Sun , Tao Li , Hao Yin , Hongzhao Xie , Jie Yin

The dynamics of gene regulatory networks is governed by the interaction between deterministic biochemical reactions and molecular noise. To understand how gene regulatory networks process information during cell state transitions, we study…

Molecular Networks · Quantitative Biology 2025-09-11 Miguel Ángel García-Ariza , Alessandro Bravetti , Pablo Padilla , J Roberto Romero-Arias

An explicit moving boundary method for the numerical solution of time-dependent hyperbolic conservation laws on grids produced by the intersection of complex geometries with a regular Cartesian grid is presented. As it employs directional…

Fluid Dynamics · Physics 2018-05-23 W. P. Bennett , N. Nikiforakis , R. Klein

We simulate a two dimensional model of self-propelled particles confined by a deformable boundary. The particles tend to accumulate near the boundary and the shape of the boundary deforms upon the collisions. We find that there are two…

Soft Condensed Matter · Physics 2018-05-18 Wen-de Tian , Yong-kun Guo , Kang Chen , Yu-qiang Ma

Phenotypic noise underpins homeostasis and fitness of individual cells. Yet, the extent to which noise shapes cell-to-population properties in microbial active matter remains poorly understood. By quantifying variability in confluent…

Biological Physics · Physics 2023-11-07 Jayabrata Dhar , Anh L. P. Thai , Arkajyoti Ghoshal , Luca Giomi , Anupam Sengupta

Generalization is one of the fundamental issues in machine learning. However, traditional techniques like uniform convergence may be unable to explain generalization under overparameterization. As alternative approaches, techniques based on…

Machine Learning · Computer Science 2022-03-22 Jiaye Teng , Jianhao Ma , Yang Yuan

Acoustic and elastic wave equations are routinely used in geophysical and engineering studies to simulate the propagation of waves, with a broad range of applications, including seismology, near surface characterization, non-destructive…

Numerical Analysis · Mathematics 2022-09-05 Longfei Gao

Model miscalibration has been frequently identified in modern deep neural networks. Recent work aims to improve model calibration directly through a differentiable calibration proxy. However, the calibration produced is often biased due to…

Machine Learning · Computer Science 2024-06-26 Cheng Wang , Jacek Golebiowski

The conventional no-slip boundary condition leads to a non-integrable stress singularity at a moving contact line. This makes numerical simulations challenging, especially when capillary effects are essential for the dynamics of the flow.…

Fluid Dynamics · Physics 2017-09-18 Hanna Holmgren , Gunilla Kreiss

Stochastic Gradient Descent (SGD) often slows in the late stage of training due to anisotropic curvature and gradient noise. We analyze preconditioned SGD in the geometry induced by a symmetric positive definite matrix $\mathbf{M}$,…

Numerical Analysis · Mathematics 2025-11-26 Mitchell Scott , Tianshi Xu , Ziyuan Tang , Alexandra Pichette-Emmons , Qiang Ye , Yousef Saad , Yuanzhe Xi

We simulate the electrical response of multiple disjoint biological 3D cells undergoing an electropermeabilization process. Instead of solving the boundary value problem in the unbounded volume, we reduce it to a system of boundary…

Computational Engineering, Finance, and Science · Computer Science 2024-09-04 Isabel A. Martínez Ávila , Carlos Jerez-Hanckes , Irina Pettersson

Neural development represents not only an exciting and complex field of study, with ongoing progress, but it also became the epicentre of neuroscience and developmental biology, as it strives to describe the underlying cellular and…

Neurons and Cognition · Quantitative Biology 2014-05-15 Ana M. Mihut , Graham Morgan , Marcus Kaiser

Audio-driven simultaneous gesture generation is vital for human-computer communication, AI games, and film production. While previous research has shown promise, there are still limitations. Methods based on VAEs are accompanied by issues…

Sound · Computer Science 2024-11-04 Yongkang Cheng , Mingjiang Liang , Shaoli Huang , Gaoge Han , Jifeng Ning , Wei Liu