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Out-of-distribution detection is crucial to the safe deployment of machine learning systems. Currently, unsupervised out-of-distribution detection is dominated by generative-based approaches that make use of estimates of the likelihood or…

Detecting anomalies in brain MRI scans using supervised deep learning methods presents challenges due to anatomical diversity and labor-intensive requirement of pixel-level annotations. Generative models like Denoising Diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Vivek Kumar Trivedi , Bheeshm Sharma , P. Balamurugan

Medical imaging data suffers from the limited availability of annotation because annotating 3D medical data is a time-consuming and expensive task. Moreover, even if the annotation is available, supervised learning-based approaches suffer…

Image and Video Processing · Electrical Eng. & Systems 2020-11-12 Abinav Ravi Venkatakrishnan , Seong Tae Kim , Rami Eisawy , Franz Pfister , Nassir Navab

Recent advances in image generation have made diffusion models powerful tools for creating high-quality images. However, their iterative denoising process makes understanding and interpreting their semantic latent spaces more challenging…

Computation and Language · Computer Science 2024-11-06 E. Zhixuan Zeng , Yuhao Chen , Alexander Wong

Recent empirical studies have demonstrated that diffusion models can effectively learn the image distribution and generate new samples. Remarkably, these models can achieve this even with a small number of training samples despite a large…

Machine Learning · Computer Science 2025-07-08 Peng Wang , Huijie Zhang , Zekai Zhang , Siyi Chen , Yi Ma , Qing Qu

Diffusion models have shown impressive performance for generative modelling of images. In this paper, we present a novel semantic segmentation method based on diffusion models. By modifying the training and sampling scheme, we show that…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Julia Wolleb , Robin Sandkühler , Florentin Bieder , Philippe Valmaggia , Philippe C. Cattin

Deep unsupervised anomaly detection in brain magnetic resonance imaging offers a promising route to identify pathological deviations without requiring lesion-specific annotations. Yet, fragmented evaluations, heterogeneous datasets, and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Alexander Frotscher , Christian F. Baumgartner , Thomas Wolfers

Anomaly detection is critical for the secure and reliable operation of industrial control systems. As our reliance on such complex cyber-physical systems grows, it becomes paramount to have automated methods for detecting anomalies,…

Machine Learning · Computer Science 2024-05-10 Mayra Macas , Chunming Wu , Walter Fuertes

Diffusion models are a special type of generative model, capable of synthesising new data from a learnt distribution. We introduce DISPR, a diffusion-based model for solving the inverse problem of three-dimensional (3D) cell shape…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Dominik J. E. Waibel , Ernst Röell , Bastian Rieck , Raja Giryes , Carsten Marr

Heterogeneous dynamics commonly emerges in anomalous diffusion with intermittent transitions of diffusion states but proves challenging to identify using conventional statistical methods. To effectively capture these transient changes of…

Biological Physics · Physics 2024-01-24 Xiang Qu , Yi Hu , Wenjie Cai , Yang Xu , Hu Ke , Guolong Zhu , Zihan Huang

A generative modeling framework is proposed that combines diffusion models and manifold learning to efficiently sample data densities on manifolds. The approach utilizes Diffusion Maps to uncover possible low-dimensional underlying (latent)…

Machine Learning · Computer Science 2025-04-22 Dimitris G. Giovanis , Ellis Crabtree , Roger G. Ghanem , Ioannis G. Kevrekidis

Diffusion generative models have emerged as a powerful framework for addressing problems in structural biology and structure-based drug design. These models operate directly on 3D molecular structures. Due to the unfavorable scaling of…

Biomolecules · Quantitative Biology 2024-05-10 Ian Dunn , David Ryan Koes

While deep neural networks (NN) significantly advance image compressed sensing (CS) by improving reconstruction quality, the necessity of training current CS NNs from scratch constrains their effectiveness and hampers rapid deployment.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Bin Chen , Zhenyu Zhang , Weiqi Li , Chen Zhao , Jiwen Yu , Shijie Zhao , Jie Chen , Jian Zhang

Inspired by recent findings that generative diffusion models learn semantically meaningful representations, we use them to discover the intrinsic hierarchical structure in biomedical 3D images using unsupervised segmentation. We show that…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Nurislam Tursynbek , Marc Niethammer

We consider the problem of anomaly detection in images, and present a new detection technique. Given a sample of images, all known to belong to a "normal" class (e.g., dogs), we show how to train a deep neural model that can detect…

Machine Learning · Computer Science 2018-11-12 Izhak Golan , Ran El-Yaniv

This report presents the comprehensive implementation, evaluation, and optimization of Denoising Diffusion Probabilistic Models (DDPMs) and Denoising Diffusion Implicit Models (DDIMs), which are state-of-the-art generative models. During…

Computer Vision and Pattern Recognition · Computer Science 2024-12-20 Jaineet Shah , Michael Gromis , Rickston Pinto

Edge detection is typically viewed as a pixel-level classification problem mainly addressed by discriminative methods. Recently, generative edge detection methods, especially diffusion model based solutions, are initialized in the edge…

Computer Vision and Pattern Recognition · Computer Science 2024-10-07 Caixia Zhou , Yaping Huang , Mochu Xiang , Jiahui Ren , Haibin Ling , Jing Zhang

Based on the Denoising Diffusion Probabilistic Model (DDPM), medical image segmentation can be described as a conditional image generation task, which allows to compute pixel-wise uncertainty maps of the segmentation and allows an implicit…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Xutao Guo , Yanwu Yang , Chenfei Ye , Shang Lu , Yang Xiang , Ting Ma

Despite the ever-increasing interest in applying deep learning (DL) models to medical imaging, the typical scarcity and imbalance of medical datasets can severely impact the performance of DL models. The generation of synthetic data that…

Image and Video Processing · Electrical Eng. & Systems 2023-04-03 Pouria Rouzrokh , Bardia Khosravi , Shahriar Faghani , Mana Moassefi , Sanaz Vahdati , Bradley J. Erickson

Computational imaging is crucial in many disciplines from autonomous driving to life sciences. However, traditional model-driven and iterative methods consume large computational power and lack scalability for imaging. Deep learning (DL) is…

Image and Video Processing · Electrical Eng. & Systems 2024-08-26 Weiru Fan , Xiaobin Tang , Yiyi Liao , Da-Wei Wang