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Related papers: Optimal Vaccination in a SIRS Epidemic Model

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Population-wide vaccination is critical for containing the SARS-CoV-2 (Covid-19) pandemic when combined with restrictive and prevention measures. In this study, we introduce SAIVR, a mathematical model able to forecast the Covid-19 epidemic…

Populations and Evolution · Quantitative Biology 2022-01-19 Mattia Angeli , Georgios Neofotistos , Marios Mattheakis , Efthimios Kaxiras

The aim of this paper is twofold. On one hand, we strive to give a simpler proof of the optimality of greedy controls when the cost of interventions is control-affine and the dynamics follow a state-constrained controlled SIR model. This is…

Optimization and Control · Mathematics 2022-05-19 Lorenzo Freddi , Dan Goreac , Juan Li , Boxiang Xu

We analyze infection spreading processes in a system where only a fraction $p$ of individuals can be affected by disease, while remaining $1-p$ individuals are immune. Such a picture can emerge as a natural consequence of previously…

Disordered Systems and Neural Networks · Physics 2021-12-06 V. Blavatska , Yu. Holovatch

We develop semiparametric methods for estimating subgroup-specific relative vaccine efficacy against multiple viral strains in a partially vaccinated population. Focusing on observational case-only studies, we address informative…

Methodology · Statistics 2025-03-12 Lars van der Laan , Peter B. Gilbert

With the present highly infectious dominant SARS-CoV-2 strain of B1.1.529 or Omicron spreading around the globe, there is concern that the COVID-19 pandemic will not end soon and that it will be a race against time until a more contagious…

Populations and Evolution · Quantitative Biology 2022-04-26 Chottiwatt Jittprasong

Epidemics have shaped human history, often with devastating consequences, motivating the development of mathematical models to understand and control their dynamics. Among the many aspects of epidemic behavior, the conditions that lead to…

Populations and Evolution · Quantitative Biology 2026-05-01 Germano Hartmann Brill , Pablo Enrique Jurado Silvestrin , Sebastian Gonçalves

Motivated by the ongoing pandemic COVID-19, we propose a closed-loop framework that combines inference from testing data, learning the parameters of the dynamics and optimal resource allocation for controlling the spread of the…

Physics and Society · Physics 2021-04-27 Ashish R. Hota , Jaydeep Godbole , Philip E Paré

We consider an SLIARS mathematical epidemiology model including intervention in the form of vaccination and treatment. Contrary to classical models, it is assumed that treatment doses can be limited in availability. Mathematically, we show…

In this research, we present an analysis of the optimal investment, consumption, and life insurance acquisition problem for a wage earner with partial information. Our study considers the non-linear filter case where risky asset prices are…

Optimization and Control · Mathematics 2023-04-25 Woundjiagué Apollinaire , Rodwell Kufakunesu , Julius Esunge

Background: Network-based interventions are most powerful against epidemics when the full network structure is known. However, resource constraints often require decisions based on partial network data. We investigated how the effectiveness…

Populations and Evolution · Quantitative Biology 2018-03-30 Yingrui Yang , Ashley McKhann , Guy Harling , Jukka-Pekka Onnela

There are few adapted SIR models in the literature that combine vaccination and logistic growth. In this article, we study bifurcations of a SIR model where the class of Susceptible individuals grows logistically and has been subject to…

Dynamical Systems · Mathematics 2023-04-26 João P. S. Maurício de Carvalho , Alexandre A. Rodrigues

The COVID-19 pandemic has devastated the world in an unprecedented way, causing enormous loss of life. Time and again, public health authorities have urged people to become vaccinated to protect themselves and mitigate the spread of the…

Systems and Control · Electrical Eng. & Systems 2021-09-30 C. H. Leung , María E. Gibbs , Philip E. Paré

In this work, we investigate a VS-EIAR epidemiological model that incorporates vaccinated individuals $\{V_i : i = 1, \ldots, n\}$, where $n \in \mathbb{N}^{*}$. The dynamics of the VS-EIAR model are governed by a system of ordinary…

Dynamical Systems · Mathematics 2025-07-16 Mamadou Abdoul Diop , Mohammed Elghandouri , Khalil Ezzinbi

Millions of young people are not immunized in low- and middle-income (LMI) countries because of low vaccine availability resulting from inefficiencies in cold supply chains. We create supply chain network design and distribution models to…

Applications · Statistics 2020-06-11 Zahra Azadi , Sandra D. Eksioglu , H. Neil Geismar

In this work, we study an epidemic model with vaccination coupled with opinion dynamics in a dynamic network. The network structure evolves as agents with differing opinions disconnect from one another and connect with agents that share…

Physics and Society · Physics 2024-01-04 Andre Oestereich , Marcelo Pires , Nuno Crokidakis , Daniel Cajueiro

Vaccination has played an important role in preventing the spread of infectious diseases. However, the limited availability of vaccines and personnel at the roll-out of a new vaccine and the costs of vaccination campaigns often limit how…

Physics and Society · Physics 2026-01-27 Rowan Hoogervorst , Evelien van der Hurk , David Pisinger

We consider the $SEIRS$ epidemiology model with such features of the COVID-19 outbreak as: abundance of unidentified infected individuals, limited time of immunity and a possibility of vaccination. Within a compartmental realization of this…

Populations and Evolution · Quantitative Biology 2021-12-07 Jaroslav Ilnytskyi , Taras Patsahan

Using the theory of Lie-Hamilton systems, formal generalized time-dependent Hamiltonian systems that enlarge a recently proposed SIS epidemic model with a variable infection rate are considered. It is shown that, independently on the…

Mathematical Physics · Physics 2023-08-10 Rutwig Campoamor-Stursberg , Eduardo Fernandez-Saiz , Francisco J. Herranz

Our paper presents three new classes of models: SIR-PH, SIR-PH-FA, and SIR-PH-IA, and states two problems we would like to solve about them. Recall that deterministic mathematical epidemiology has one basic general law, the R0 alternative"…

Populations and Evolution · Quantitative Biology 2022-05-10 Florin Avram , Rim Adenane , Andrei Halanay

The dynamics of a SIVR model with power relationship incidence rates $(\beta I^p S^q)$ is investigated. It is assumed an individual can be susceptible after receiving the first dose of the vaccine, hence a second dose is required to attain…

Populations and Evolution · Quantitative Biology 2019-05-06 Gabriel O. Fosu , Emmanuel K. Mintah