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Related papers: Optimal Vaccination in a SIRS Epidemic Model

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In this paper we consider SIR epidemics on random graphs with clustering. To incorporate group structure of the underlying social network, we use a generalized version of the configuration model in which each node is a member of a specified…

Probability · Mathematics 2018-02-15 Carolina Fransson , Pieter Trapman

In the context of SARS-CoV-2 pandemic, mathematical modelling has played a fundamental role for making forecasts, simulating scenarios and evaluating the impact of preventive political, social and pharmaceutical measures. Optimal control…

Optimization and Control · Mathematics 2022-11-01 Giovanni Ziarelli , Luca Dede' , Nicola Parolini , Marco Verani , Alfio Quarteroni

Until a vaccine or therapy is found against the SARS-CoV-2 coronavirus, reaching herd immunity appears to be the only mid-term option. However, if the number of infected individuals decreases and eventually fades only beyond this threshold,…

Optimization and Control · Mathematics 2020-06-11 Pierre-Alexandre Bliman , Michel Duprez , Yannick Privat , Nicolas Vauchelet

We analyse an extended SIRS epidemic model in which immunity at the individual level wanes gradually at exponential rate, but where the waning rate may differ between individuals, for instance as an effect of differences in immune systems.…

Populations and Evolution · Quantitative Biology 2023-11-02 Mohamed El Khalifi , Tom Britton

This study presents a family of stochastic models for the dynamics of influenza in a closed human population. We consider treatment for the disease in the form of vaccination, and incorporate the periods of effectiveness of the vaccine and…

Populations and Evolution · Quantitative Biology 2020-05-05 Divine Wanduku

In this paper, an SIR epidemic model with variable size of population is considered. We study optimal control problem for an SIR model with "vaccination" and "treatment" as controls. It is shown that an optimal control exists. We have…

Optimization and Control · Mathematics 2016-12-28 Olga Klimenkova

Since early 2020, the world has been dealing with a raging pandemic outbreak: COVID-19. A year later, vaccines have become accessible, but in limited quantities, so that governments needed to devise a strategy to decide which part of the…

Populations and Evolution · Quantitative Biology 2022-04-13 Sander Tonkens , Paul de Klaver , Mauro Salazar

This present results lay the foundations for the study of the optimal allocation of vaccine in the simple epidemiological SIS model where one consider a very general heterogeneous population. In the present setting each individual has a…

Populations and Evolution · Quantitative Biology 2025-04-02 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

This is an epidemiological SIRV model based study that is designed to analyze the impact of vaccination in containing infection spread, in a 4-tiered population compartment comprised of susceptible, infected, recovered and vaccinated…

Populations and Evolution · Quantitative Biology 2018-11-14 Ewa Grela , Michael Stich , Amit K Chattopadhyay

We examine here the effects of recurrent vaccination and waning immunity on the establishment of an endemic equilibrium in a population. An individual-based model that incorporates memory effects for transmission rate during infection and…

Populations and Evolution · Quantitative Biology 2024-11-22 Félix Foutel-Rodier , Arthur Charpentier , Hélène Guérin

We develop a mechanistic model that classifies individuals both in terms of epidemiological status (SIR) and vaccination attitude (willing or unwilling), with the goal of discovering how disease spread is influenced by changing opinions…

Dynamical Systems · Mathematics 2024-08-16 Yi Jiang , Kristin M. Kurianski , Jane HyoJin Lee , Yanping Ma , Daniel Cicala , Glenn Ledder

Since the recent introduction of several viable vaccines for SARS-CoV-2, vaccination uptake has become the key factor that will determine our success in containing the COVID-19 pandemic. We argue that game theory and social network models…

This paper deals with an SIR model with saturated incidence rate affected by inhibitory effect and saturated treatment function. Two control functions have been used, one for vaccinating the susceptible population and other for the…

Dynamical Systems · Mathematics 2018-07-17 Jayanta Kumar Ghosh , Uttam Ghosh , M. H. A. Biswas , Susmita Sarkar

In this paper we aim to study an optimal insurance premium level for health-care in a deterministic and stochastic SIR models with migration fluxes and vaccination of population. The studied model considers two standard SIR centres…

Populations and Evolution · Quantitative Biology 2019-10-14 Aleksandr A. Shemendyuk , Alexey A. Chernov , Mark Y Kelbert

We devise a theoretical model for the optimal dynamical control of an infectious disease whose diffusion is described by the SVIR compartmental model. The control is realized through implementing social rules to reduce the disease's spread,…

Optimization and Control · Mathematics 2022-08-10 Alessandro Ramponi , Maria Elisabetta Tessitore

In previous articles, we formalized the problem of optimal allocation strategies for a (perfect) vaccine in an infinite-dimensional metapopulation model. The aim of the current paper is to illustrate this theoretical framework with multiple…

Optimization and Control · Mathematics 2021-12-17 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

An integrable discretization of the SIR model with vaccination is proposed. The conserved quantities of the continuous model are inherited to the discrete model through the discretization, since the discretization is based on the…

Exactly Solvable and Integrable Systems · Physics 2023-03-31 Atsushi Nobe

This paper presents a study on a compartmental epidemic model for COVID-19, examining the stability of its equilibrium points upon the introduction of vaccination as a strategy to mitigate the spread of the disease. Initially, the SIQR…

Numerical Analysis · Mathematics 2024-05-29 Leonardo R. S. Rodrigues , Felipe Gabrielli

We consider the SEIRS epidemiology model with such features of the COVID-19 outbreak as: abundance of unidentified infected individuals, limited time of immunity and a possibility of vaccination. The control of the pandemic dynamics is…

Populations and Evolution · Quantitative Biology 2026-03-31 J. Ilnytskyi , T. Patsahan

This paper is concerned with an optimal reinsurance and investment problem for an insurance firm under the criterion of mean-variance. The driving Brownian motion and the rate in return of the risky asset price dynamic equation cannot be…

Optimization and Control · Mathematics 2020-06-04 Shihao Zhu , Jingtao Shi