Related papers: Petri nets in epidemiology
The basic reproduction number ($R_0$) is an epidemiological metric that represents the average number of new infections caused by a single infectious individual in a completely susceptible population. The methodology for calculating this…
Accurate epidemic forecasting requires models that account for the layered and heterogeneous nature of real social interactions. The basic reproduction number $\mathcal R_0$ calculated from models that assume homogeneous mixing or…
Petri Nets are an increasingly used modeling framework for the spread of disease across populations or within an individual. For example, the Susceptible-Infectious-Recovered (SIR) compartment model is foundational for population…
In the real world, many complex systems interact with other systems. In addition, the intra- or inter-systems for the spread of information about infectious diseases and the transmission of infectious diseases are often not random, but with…
The basic and effective reproduction numbers are widely used metrics for characterizing the dynamics of infectious disease epidemics. However, the interpretation of these numbers is based on the assumption of homogeneous mixing and may not…
In this paper, we provide a straightforward approach to defining and deriving the key epidemiological quantity, the basic reproduction number, $R_0$, for Markovian epidemics in structured populations. The methodology derived is applicable…
For a heterogeneous host population, the basic reproduction number of an infectious disease, $\cR_0$, is defined as the spectral radius of the next generation operator (NGO). The threshold properties of the basic reproduction number are…
The duration, type and structure of connections between individuals in real-world populations play a crucial role in how diseases invade and spread. Here, we incorporate the aforementioned heterogeneities into a model by considering a…
In epidemiological modelings, the spectral radius of the next generation matrix evaluated at the trivial equilibrium was considered as the basic reproduction number. Also, the global stability of the trivial equilibrium point was determined…
Real epidemic spreading networks often composed of several kinds of networks interconnected with each other, and the interrelated networks have the different topologies and epidemic dynamics. Moreover, most human diseases are derived from…
We propose a novel approach to approximate the basic reproduction number $R_0$ as spectral radius of the Next-Generation Operator in time-periodic population models by characterizing the latter via evolution semigroups. Once birth/infection…
Reproduction numbers, like the basic reproduction number $\mathcal{R}_0$, play an important role in the analysis and application of dynamic models, including contagion models and ecological population models. One difficulty in deriving…
A key parameter in models for the spread of infectious diseases is the basic reproduction number $R_0$, which is the expected number of secondary cases a typical infected primary case infects during its infectious period in a large mostly…
In this paper, we consider the infection-age-dependent Kermack--McKendrick model in which host individuals are distributed in a continuous state space. To provide a mathematical foundation for the heterogeneous model, we develop a…
We present a methodology for systematically extending epidemic models to multilevel and multiscale spatio-temporal pandemic ones. Our approach builds on the use of coloured stochastic and continuous Petri nets facilitating the sound…
As widely known, the basic reproduction number plays a key role in weighing birth/infection and death/recovery processes in several models of population dynamics. In this general setting, its characterization as the spectral radius of next…
Reproduction numbers are widely used for the estimation and prediction of epidemic spreading processes over networks. However, reproduction numbers do not enable estimation and prediction in individual communities within networks, and they…
Due to its ability to summarise 'real-time' epidemic behaviour, the time-dependent reproduction number, Rt, is a useful metric for tracking pathogen transmission and quantifying the effects of interventions during infectious disease…
The celebrated Kermack-McKendric model of epidemics studies the transmission of a disease in a population where each individual is initially susceptible (S), may become infective (I) and then removed or recovered (R) and plays no further…
In this paper we consider epidemic models of directly transmissible SIR (susceptible $\to$ infective $\to$ recovered) and SEIR (with an additional latent class) infections in fully-susceptible populations with a social structure, consisting…