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We are developing a computer-aided detection (CAD) system for the identification of small pulmonary nodules in screening CT scans. The main modules of our system, i.e. a dot-enhancement filter for nodule candidate selection and a neural…

Medical Physics · Physics 2009-04-15 P. Delogu , M. E. Fantacci , I. Gori , A. Preite Martinez , A. Retico , A. Tata

Diagnosing lung cancer typically involves physicians identifying lung nodules in Computed tomography (CT) scans and generating diagnostic reports based on their morphological features and medical expertise. Although advancements have been…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Cheng Yang , Hui Jin , Xinlei Yu , Zhipeng Wang , Yaoqun Liu , Fenglei Fan , Dajiang Lei , Gangyong Jia , Changmiao Wang , Ruiquan Ge

Pulmonary emphysema overlaps considerably with chronic obstructive pulmonary disease (COPD), and is traditionally subcategorized into three subtypes previously identified on autopsy. Unsupervised learning of emphysema subtypes on computed…

Computer Vision and Pattern Recognition · Computer Science 2020-07-10 Jie Yang , Elsa D. Angelini , Pallavi P. Balte , Eric A. Hoffman , John H. M. Austin , Benjamin M. Smith , R. Graham Barr , Andrew F. Laine

Pulmonary emphysema, the progressive, irreversible loss of lung tissue, is conventionally categorized into three subtypes identifiable on pathology and on lung computed tomography (CT) images. Recent work has led to the unsupervised…

Automated detection and segmentation of pulmonary nodules on lung computed tomography (CT) scans can facilitate early lung cancer diagnosis. Existing supervised approaches for automated nodule segmentation on CT scans require voxel-based…

Computer Vision and Pattern Recognition · Computer Science 2018-02-26 Xinyang Feng , Jie Yang , Andrew F. Laine , Elsa D. Angelini

Objective: Although medical imaging datasets are increasingly available, abnormal and annotation-intensive findings critical to lung cancer screening, particularly small pulmonary nodules, remain underrepresented and inconsistently curated.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Fakrul Islam Tushar , Ehsan Samei , Cynthia Rudin , Joseph Y. Lo

Lung cancer is a leading cause of death worldwide and early screening is critical for improving survival outcomes. In clinical practice, the contextual structure of nodules and the accumulated experience of radiologists are the two core…

Image and Video Processing · Electrical Eng. & Systems 2023-07-21 Jianpeng Zhang , Xianghua Ye , Jianfeng Zhang , Yuxing Tang , Minfeng Xu , Jianfei Guo , Xin Chen , Zaiyi Liu , Jingren Zhou , Le Lu , Ling Zhang

We investigate the addition of symmetry and temporal context information to a deep Convolutional Neural Network (CNN) with the purpose of detecting malignant soft tissue lesions in mammography. We employ a simple linear mapping that takes…

Computer Vision and Pattern Recognition · Computer Science 2017-08-02 Thijs Kooi , Nico Karssemeijer

Pulmonary nodules are critical indicators for the early diagnosis of lung cancer, making their detection essential for timely treatment. However, traditional CT imaging methods suffered from cumbersome procedures, low detection rates, and…

Image and Video Processing · Electrical Eng. & Systems 2025-01-29 Guohui Cai , Ruicheng Zhang , Hongyang He , Zeyu Zhang , Daji Ergu , Yuanzhouhan Cao , Jinman Zhao , Binbin Hu , Zhinbin Liao , Yang Zhao , Ying Cai

Accurate detection of pulmonary nodules with high sensitivity and specificity is essential for automatic lung cancer diagnosis from CT scans. Although many deep learning-based algorithms make great progress for improving the accuracy of…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Jingya Liu , Liangliang Cao , Oguz Akin , Yingli Tian

Time-series remote sensing data offer a rich source of information that can be used in a wide range of applications, from monitoring changes in land cover to surveilling crops, coastal changes, flood risk assessment, and urban sprawl. This…

Computer Vision and Pattern Recognition · Computer Science 2021-03-03 Wadii Boulila , Hamza Ghandorh , Mehshan Ahmed Khan , Fawad Ahmed , Jawad Ahmad

Though large-scale datasets are essential for training deep learning systems, it is expensive to scale up the collection of medical imaging datasets. Synthesizing the objects of interests, such as lung nodules, in medical images based on…

Computer Vision and Pattern Recognition · Computer Science 2019-01-01 Jie Yang , Siqi Liu , Sasa Grbic , Arnaud Arindra Adiyoso Setio , Zhoubing Xu , Eli Gibson , Guillaume Chabin , Bogdan Georgescu , Andrew F. Laine , Dorin Comaniciu

Accurately predicting and detecting interstitial lung disease (ILD) patterns given any computed tomography (CT) slice without any pre-processing prerequisites, such as manually delineated regions of interest (ROIs), is a clinically…

Computer Vision and Pattern Recognition · Computer Science 2017-01-23 Mingchen Gao , Ziyue Xu , Le Lu , Adam P. Harrison , Ronald M. Summers , Daniel J. Mollura

Pathologies systematically induce morphological changes, thus providing a major but yet insufficiently quantified source of observables for diagnosis. The study develops a predictive model of the pathological states based on morphological…

Lymph node metastasis (LNM) is a significant prognostic factor in patients with head and neck cancer, and the ability to predict it accurately is essential for treatment optimization. PET and CT imaging are routinely used for LNM…

Predicting the risk of developing breast cancer is an important clinical tool to guide early intervention and tailoring personalized screening strategies. Early risk models have limited performance and recently machine learning-based…

Image and Video Processing · Electrical Eng. & Systems 2025-05-29 Zhengbo Zhou , Dooman Arefan , Margarita Zuley , Jules Sumkin , Shandong Wu

Lung cancer is a leading cause of death in most countries of the world. Since prompt diagnosis of tumors can allow oncologists to discern their nature, type and the mode of treatment, tumor detection and segmentation from CT Scan images is…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Farhanaz Farheen , Md. Salman Shamil , Nabil Ibtehaz , M. Sohel Rahman

In this paper, we propose a novel framework with 3D convolutional networks (ConvNets) for automated detection of pulmonary nodules from low-dose CT scans, which is a challenging yet crucial task for lung cancer early diagnosis and…

Computer Vision and Pattern Recognition · Computer Science 2017-08-15 Qi Dou , Hao Chen , Yueming Jin , Huangjing Lin , Jing Qin , Pheng-Ann Heng

Lung cancer(LC) is a type of malignant neoplasm that originates in the bronchial mucosa or glands.As a clinically common nodule,solitary pulmonary nodules(SPNs) have a significantly higher probability of malignancy when they are larger than…

Quantitative Methods · Quantitative Biology 2023-05-19 Hailan Zhang , Gongjin Song

In the U.S., lung cancer is the second major cause of death. Early detection of suspicious lung nodules is crucial for patient treatment planning, management, and improving outcomes. Many approaches for lung nodule segmentation and…

Image and Video Processing · Electrical Eng. & Systems 2025-04-10 Tejas Sudharshan Mathai , Benjamin Hou , Ronald M. Summers
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