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Drug-drug interaction prediction is a crucial issue in molecular biology. Traditional methods of observing drug-drug interactions through medical experiments require significant resources and labor. This paper presents a medical knowledge…

Computation and Language · Computer Science 2024-07-29 Peng Gao , Feng Gao , Jian-Cheng Ni , Yu Wang , Fei Wang

The recent proliferation of knowledge graphs (KGs) coupled with incomplete or partial information, in the form of missing relations (links) between entities, has fueled a lot of research on knowledge base completion (also known as relation…

Machine Learning · Computer Science 2019-06-05 Deepak Nathani , Jatin Chauhan , Charu Sharma , Manohar Kaul

Knowledge Graphs (KGs) and their machine learning counterpart, Knowledge Graph Embedding Models (KGEMs), have seen ever-increasing use in a wide variety of academic and applied settings. In particular, KGEMs are typically applied to KGs to…

Machine Learning · Computer Science 2024-12-16 Jeffrey Sardina , John D. Kelleher , Declan O'Sullivan

Graph learning methods have been extensively applied in diverse application areas. However, what kind of inherent graph properties e.g. graph proximity, graph structural information has been encoded into graph representation learning for…

Machine Learning · Computer Science 2024-08-08 Mingyu Zhao , Xingyu Huang , Ziyu Lyu , Yanlin Wang , Lixin Cui , Lu Bai

Embedding learning, a.k.a. representation learning, has been shown to be able to model large-scale semantic knowledge graphs. A key concept is a mapping of the knowledge graph to a tensor representation whose entries are predicted by models…

Machine Learning · Computer Science 2015-12-23 Cristóbal Esteban , Volker Tresp , Yinchong Yang , Stephan Baier , Denis Krompaß

Protein representation learning has primarily benefited from the remarkable development of language models (LMs). Accordingly, pre-trained protein models also suffer from a problem in LMs: a lack of factual knowledge. The recent solution…

Machine Learning · Computer Science 2023-02-16 Hong-Yu Zhou , Yunxiang Fu , Zhicheng Zhang , Cheng Bian , Yizhou Yu

Knowledge Graph Embedding (KGE) methods have gained enormous attention from a wide range of AI communities including Natural Language Processing (NLP) for text generation, classification and context induction. Embedding a huge number of…

Artificial Intelligence · Computer Science 2022-09-19 Mojtaba Moattari , Sahar Vahdati , Farhana Zulkernine

Human knowledge provides a formal understanding of the world. Knowledge graphs that represent structural relations between entities have become an increasingly popular research direction towards cognition and human-level intelligence. In…

Computation and Language · Computer Science 2021-04-02 Shaoxiong Ji , Shirui Pan , Erik Cambria , Pekka Marttinen , Philip S. Yu

We propose a method for gene expression based analysis of cancer phenotypes incorporating network biology knowledge through unsupervised construction of computational graphs. The structural construction of the computational graphs is driven…

Molecular Networks · Quantitative Biology 2020-10-02 Paul Scherer , Maja Trȩbacz , Nikola Simidjievski , Zohreh Shams , Helena Andres Terre , Pietro Liò , Mateja Jamnik

We study the problem of learning representations of entities and relations in knowledge graphs for predicting missing links. The success of such a task heavily relies on the ability of modeling and inferring the patterns of (or between) the…

Machine Learning · Computer Science 2019-02-28 Zhiqing Sun , Zhi-Hong Deng , Jian-Yun Nie , Jian Tang

The ability of knowledge graphs to represent complex relationships at scale has led to their adoption for various needs including knowledge representation, question-answering, and recommendation systems. Knowledge graphs are often…

Computation and Language · Computer Science 2023-05-18 Jason Youn , Ilias Tagkopoulos

Proteins play a vital role in biological processes and are indispensable for living organisms. Accurate representation of proteins is crucial, especially in drug development. Recently, there has been a notable increase in interest in…

Biomolecules · Quantitative Biology 2026-05-28 Dan Kalifa , Uriel Singer , Kira Radinsky

Graph-based machine learning methods are useful tools in the identification and prediction of variation in genetic data. In particular, the comprehension of phenotypic effects at the cellular level is an accelerating research area in…

Quantitative Methods · Quantitative Biology 2024-12-06 Nandini Gadhia , Michalis Smyrnakis , Po-Yu Liu , Damer Blake , Melanie Hay , Anh Nguyen , Dominic Richards , Dong Xia , Ritesh Krishna

Many models learn representations of knowledge graph data by exploiting its low-rank latent structure, encoding known relations between entities and enabling unknown facts to be inferred. To predict whether a relation holds between…

Machine Learning · Computer Science 2021-01-19 Carl Allen , Ivana Balažević , Timothy Hospedales

Graph embedding learning that aims to automatically learn low-dimensional node representations, has drawn increasing attention in recent years. To date, most recent graph embedding methods are evaluated on social and information networks…

Information extraction methods proved to be effective at triple extraction from structured or unstructured data. The organization of such triples in the form of (head entity, relation, tail entity) is called the construction of Knowledge…

Artificial Intelligence · Computer Science 2022-08-25 Mohamad Zamini , Hassan Reza , Minou Rabiei

Knowledge graphs are graphical representations of large databases of facts, which typically suffer from incompleteness. Inferring missing relations (links) between entities (nodes) is the task of link prediction. A recent state-of-the-art…

Machine Learning · Computer Science 2019-09-12 Ivana Balažević , Carl Allen , Timothy M. Hospedales

The majority of knowledge graph embedding techniques treat entities and predicates as separate embedding matrices, using aggregation functions to build a representation of the input triple. However, these aggregations are lossy, i.e. they…

Computation and Language · Computer Science 2022-08-23 Alexander Kalinowski , Yuan An

Low-dimensional embeddings of nodes in large graphs have proved extremely useful in a variety of prediction tasks, from content recommendation to identifying protein functions. However, most existing approaches require that all nodes in the…

Social and Information Networks · Computer Science 2018-09-11 William L. Hamilton , Rex Ying , Jure Leskovec

Knowledge Graph (KG) alignment is to discover the mappings (i.e., equivalent entities, relations, and others) between two KGs. The existing methods can be divided into the embedding-based models, and the conventional reasoning and lexical…

Computation and Language · Computer Science 2021-06-14 Zhiyuan Qi , Ziheng Zhang , Jiaoyan Chen , Xi Chen , Yuejia Xiang , Ningyu Zhang , Yefeng Zheng