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Complex biological functions are carried out by the interaction of genes and proteins. Uncovering the gene regulation network behind a function is one of the central themes in biology. Typically, it involves extensive experiments of…

Quantitative Methods · Quantitative Biology 2020-02-25 Jingxiang Shen , Mariela D. Petkova , Yuhai Tu , Feng Liu , Chao Tang

The goal of this document is to provide a pedagogical introduction to the main concepts underpinning the training of deep neural networks using gradient descent; a process known as backpropagation. Although we focus on a very influential…

Machine Learning · Computer Science 2018-11-30 Laurent Boué

Learning how complex dynamical systems evolve over time is a key challenge in system identification. For safety critical systems, it is often crucial that the learned model is guaranteed to converge to some equilibrium point. To this end,…

Machine Learning · Computer Science 2021-12-13 Andreas Schlaginhaufen , Philippe Wenk , Andreas Krause , Florian Dörfler

Recurrent Neural Networks (RNNs) have shown great success in modeling time-dependent patterns, but there is limited research on their learned representations of latent temporal features and the emergence of these representations during…

Machine Learning · Computer Science 2023-06-13 Peter DelMastro , Rushiv Arora , Edward Rietman , Hava T. Siegelmann

This paper investigates efficient deep neural networks (DNNs) to replace dense unstructured weight matrices with structured ones that possess desired properties. The challenge arises because the optimal weight matrix structure in popular…

Machine Learning · Computer Science 2024-03-11 Changwoo Lee , Hun-Seok Kim

Empirically observed time series in physics, biology, or medicine, are commonly generated by some underlying dynamical system (DS) which is the target of scientific interest. There is an increasing interest to harvest machine learning…

Machine Learning · Computer Science 2022-07-07 Daniel Kramer , Philine Lou Bommer , Carlo Tombolini , Georgia Koppe , Daniel Durstewitz

Deep neural networks (DNNs) have become powerful tools for modeling complex data structures through sequentially integrating simple functions in each hidden layer. In survival analysis, recent advances of DNNs primarily focus on enhancing…

Machine Learning · Statistics 2025-03-26 Changhui Yuan , Shishun Zhao , Shuwei Li , Xinyuan Song , Zhao Chen

Deep neural networks, albeit their great success on feature learning in various computer vision tasks, are usually considered as impractical for online visual tracking because they require very long training time and a large number of…

Computer Vision and Pattern Recognition · Computer Science 2016-05-04 Hanxi Li , Yi Li , Fatih Porikli

The robotic systems continuously interact with complex dynamical systems in the physical world. Reliable predictions of spatiotemporal evolution of these dynamical systems, with limited knowledge of system dynamics, are crucial for…

Artificial Intelligence · Computer Science 2019-01-08 Yun Long , Xueyuan She , Saibal Mukhopadhyay

Background: It is still an open research area to theoretically understand why Deep Neural Networks (DNNs)---equipped with many more parameters than training data and trained by (stochastic) gradient-based methods---often achieve remarkably…

Machine Learning · Computer Science 2018-11-30 Zhiqin John Xu

The study of mechanistic interpretability aims to reverse-engineer a model to explain its behaviors. While recent studies have focused on the static mechanism of a certain behavior, the learning dynamics inside a model remain to be…

Machine Learning · Computer Science 2025-09-24 Yueyan Li , Wenhao Gao , Caixia Yuan , Xiaojie Wang

Unsupervised dimensionality reduction is one of the commonly used techniques in the field of high dimensional data recognition problems. The deep autoencoder network which constrains the weights to be non-negative, can learn a low…

Computer Vision and Pattern Recognition · Computer Science 2020-09-18 Anyong Qin , Zhaowei Shang , Zhuolin Tan , Taiping Zhang , Yuan Yan Tang

Deep neural networks (DNNs) are powerful learning machines that have enabled breakthroughs in several domains. In this work, we introduce a new retrospective loss to improve the training of deep neural network models by utilizing the prior…

Computer Vision and Pattern Recognition · Computer Science 2020-06-25 Surgan Jandial , Ayush Chopra , Mausoom Sarkar , Piyush Gupta , Balaji Krishnamurthy , Vineeth Balasubramanian

Advancements in deep learning are revolutionizing science and engineering. The immense success of deep learning is largely due to its ability to extract essential high-dimensional (HD) features from input data and make inference decisions…

Machine Learning · Computer Science 2025-01-30 Md Tauhidul Islam , Lei Xing

Powerful deep learning tools, such as convolutional neural networks (CNN), are able to learn the input-output relationships of large complicated systems directly from data. Encoder-decoder deep CNNs are able to extract features directly…

Machine Learning · Statistics 2021-06-08 Alexander Scheinker , Frederick Cropp , Sergio Paiagua , Daniele Filippetto

A properly designed controller can help improve the quality of experimental measurements or force a dynamical system to follow a completely new time-evolution path. Recent developments in deep reinforcement learning have made steep advances…

Statistical Mechanics · Physics 2025-02-26 Ruslan Mukhamadiarov

Many dynamical processes of complex systems can be understood as the dynamics of a group of nodes interacting on a given network structure. However, finding such interaction structure and node dynamics from time series of node behaviours is…

Physics and Society · Physics 2022-06-28 Yan Zhang , Yu Guo , Zhang Zhang , Mengyuan Chen , Shuo Wang , Jiang Zhang

Deep neural networks (DNNs) are increasingly deployed in different applications to achieve state-of-the-art performance. However, they are often applied as a black box with limited understanding of what knowledge the model has learned from…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Shihao Zhao , Xingjun Ma , Yisen Wang , James Bailey , Bo Li , Yu-Gang Jiang

Convolutional Neural Networks (CNNs) achieve state-of-the-art performance in many computer vision tasks. However, this achievement is preceded by extreme manual annotation in order to perform either training from scratch or fine-tuning for…

Computer Vision and Pattern Recognition · Computer Science 2016-09-08 Filip Radenović , Giorgos Tolias , Ondřej Chum

Learning long-term behaviors in chaotic dynamical systems, such as turbulent flows and climate modelling, is challenging due to their inherent instability and unpredictability. These systems exhibit positive Lyapunov exponents, which…

Chaotic Dynamics · Physics 2025-04-02 Xiaoyuan Cheng , Yi He , Yiming Yang , Xiao Xue , Sibo Cheng , Daniel Giles , Xiaohang Tang , Yukun Hu