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The classical macroscopic chemotaxis equations have previously been derived from an individual-based description of the tactic response of cells that use a "run-and-tumble" strategy in response to environmental cues. Here we derive…

Cell Behavior · Quantitative Biology 2007-05-23 Radek Erban , Hans G. Othmer

Motivated by observations of the dynamics of {\it Myxococcus xanthus}, we present a self-interacting random walk model that describes the competition between chemokinesis and chemotaxis. Cells are constrained to move in one dimension, but…

Statistical Mechanics · Physics 2016-08-31 Maria R. D'Orsogna , Marc Suchard , Tom Chou

Micro-swimmers such as bacteria perform random walks known as run-and-tumbles to move up chemo-attractant gradients and as a result aggregate with others. It is also known that such micro-swimmers can self-organize into macroscopic patterns…

Biological Physics · Physics 2016-08-31 Enkeleida Lushi

Escherichia coli has long been used as a model organism due to the extensive experimental characterization of its pathways and molecular components. Take chemotaxis as an example, which allows bacteria to sense and swim in response to…

Cell Behavior · Quantitative Biology 2015-12-09 Gabriele Micali , Robert G. Endres

Swimming bacteria detect chemical gradients by performing temporal comparisons of recent measurements of chemical concentration. These comparisons are described quantitatively by the chemotactic response function, which we expect to…

Cell Behavior · Quantitative Biology 2009-11-13 Damon A. Clark , Lars C. Grant

Chemotaxis is a directed cell movement in response to external chemical stimuli. In this paper, we propose a simple model for the origin of chemotaxis - namely how a directed movement in response to an external chemical signal may occur…

Analysis of PDEs · Mathematics 2023-06-30 Yishu Gong , Alexander Kiselev

{\it E. coli} bacteria swim in straight runs interrupted by sudden reorientation events called tumbles. The resulting random walks give rise to density fluctuations that can be derived analytically in the limit of non interacting particles…

Statistical Mechanics · Physics 2013-09-05 M. Paoluzzi , R. Di Leonardo , L. Angelani

Most of our understanding of bacterial chemotaxis comes from studies of Escherichia coli. However, recent evidence suggests significant departures from the E. coli paradigm in other bacterial species. This variation may stem from different…

Cell Behavior · Quantitative Biology 2015-03-27 Martin Godány , Bhavin S. Khatri , Richard A. Goldstein

Microbiology is the science of microbes, particularly bacteria. Many bacteria are motile: they are capable of self-propulsion. Among these, a significant class execute so-called run-and-tumble motion: they follow a fairly straight path for…

Statistical Mechanics · Physics 2012-09-06 M. E. Cates

Bacterial chemotaxis is one of the most extensively studied adaptive responses in cells. Many bacteria are able to bias their apparently random motion to produce a drift in the direction of the increasing chemoattractant concentration. It…

Soft Condensed Matter · Physics 2018-02-07 E. V. Pankratova , A. I. Kalyakulina , M. I. Krivonosov , S. Denisov , K. M. Taute , V. Yu. Zaburdaev

Colonies of bacteria grown on thin agar plate exhibit fractal patterns as a result of adaptation to their environments. The bacterial colony pattern formation is regulated crucially by chemotaxis, the movement of cells along a chemical…

Biological Physics · Physics 2013-05-24 Waipot Ngamsaad , Kannika Khompurngson

Bacteria track chemical gradients using a biased random walk, a process called chemotaxis. Experiments suggest that bacteria also communicate during this process. Using a mathematical model, we find that sufficiently strong communication…

Biological Physics · Physics 2025-12-18 Soutick Saha , Sean Fancher , Andrew Mugler

Bacteria are able to respond to environmental signals by changing their rules of movement. When we take into account chemical signals in the environment, this behaviour is often called chemotaxis. At the individual-level, chemotaxis…

Analysis of PDEs · Mathematics 2007-05-23 Radek Erban , Hyung Ju Hwang

Bacterial chemotaxis has long been viewed as operating near the physical limits of sensing, as originally articulated by Berg and Purcell. Recent information-theoretic analyses challenge this view, suggesting that Escherichia coli uses only…

Cell Behavior · Quantitative Biology 2026-05-06 Robert G. Endres

Chemotaxis refers to the directed movement of cells in response to a chemical signal called chemoattractant. A crucial point in the mathematical modeling of chemotactic processes is the correct description of the chemotactic sensitivity and…

Analysis of PDEs · Mathematics 2015-01-08 Herbert Egger , Jan-Frederik Pietschmann , Matthias Schlottbom

Many phenomena in biology involve both reactions and chemotaxis. These processes can clearly influence each other, and chemotaxis can play an important role in sustaining and speeding up the reaction. In continuation of our earlier work, we…

Analysis of PDEs · Mathematics 2015-06-04 Alexander Kiselev , Lenya Ryzhik

Models for chemotaxis are based on gradient sensing of individual organisms. The key contribution of Keller and Segel is showing that erratic movements of individuals may result in an accurate chemotaxis phenomenon as a group. In this paper…

Populations and Evolution · Quantitative Biology 2013-07-31 Changwook Yoon , Yong-Jung Kim

Bacterial chemotaxis is controlled by the conformational changes of the receptors, in response to the change of the ambient chemical concentration. In a statistical mechanical approach, the signalling due to the conformational changes is a…

Biological Physics · Physics 2009-11-07 Yu Shi

Chemotaxis describes the intricate interplay of cellular motion in response to a chemical signal. We here consider the case of slab geometry which models chemotactic motion between two infinite membranes. Like previous works, we are…

Analysis of PDEs · Mathematics 2026-01-16 Herbert Egger , Kathrin Hellmuth , Nora Philippi , Matthias Schlottbom

Chemotaxis and haptotaxis have been a main theme in the macroscopic study of bacterial and cellular motility. In this work we investigate the influence these processes have on the shape and motility of fast migrating cells. We note that…

Cell Behavior · Quantitative Biology 2016-12-08 Aaron Brunk , Niklas Kolbe , Nikolaos Sfakianakis