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Electronic health records (EHRs) enable strong clinical prediction, but explanations are often coarse and hard to use for patient-level decisions. We propose a knowledge graph (KG)-guided chain-of-thought (CoT) framework for visit-level…

Artificial Intelligence · Computer Science 2026-03-03 Ruiyu Wang , Tuan Vinh , Ran Xu , Yuyin Zhou , Jiaying Lu , Carl Yang , Francisco Pasquel

The development of electronic health records (EHR) systems has enabled the collection of a vast amount of digitized patient data. However, utilizing EHR data for predictive modeling presents several challenges due to its unique…

Machine Learning · Computer Science 2024-08-14 Jiaqi Wang , Junyu Luo , Muchao Ye , Xiaochen Wang , Yuan Zhong , Aofei Chang , Guanjie Huang , Ziyi Yin , Cao Xiao , Jimeng Sun , Fenglong Ma

Previous cross-lingual knowledge graph (KG) alignment studies rely on entity embeddings derived only from monolingual KG structural information, which may fail at matching entities that have different facts in two KGs. In this paper, we…

Machine Learning · Computer Science 2019-07-31 Kun Xu , Liwei Wang , Mo Yu , Yansong Feng , Yan Song , Zhiguo Wang , Dong Yu

The increasing availability of unstructured clinical narratives in electronic health records (EHRs) has created new opportunities for automated disease characterization, cohort identification, and clinical decision support. However,…

Computation and Language · Computer Science 2026-03-03 Fariba Afrin Irany , Sampson Akwafuo

Objective: To transform heterogeneous clinical data from electronic health records into clinically meaningful constructed features using data driven method that rely, in part, on temporal relations among data. Materials and Methods: The…

Machine Learning · Computer Science 2017-06-22 Edward Choi , Andy Schuetz , Walter F. Stewart , Jimeng Sun

In the past decade, with the development of big data technology, an increasing amount of patient information has been stored as electronic health records (EHRs). Leveraging these data, various doctor recommendation systems have been…

Information Retrieval · Computer Science 2022-07-14 Luning Bi , Yunlong Wang , Fan Zhang , Zhuqing Liu , Yong Cai , Emily Zhao

Electronic Health Records (EHRs) contain rich, longitudinal patient information across structured (e.g., labs, vitals, and imaging) and unstructured (e.g., clinical notes) modalities. While deep learning models such as RNNs and Transformers…

Machine Learning · Computer Science 2026-02-18 Mohammad Al Olaimat , Shaika Chowdhury , Serdar Bozdag

Electronic health records (EHRs) are invaluable for clinical research, yet privacy concerns severely restrict data sharing. Synthetic data generation offers a promising solution, but EHRs present unique challenges: they contain both…

Machine Learning · Computer Science 2026-03-26 Shaonan Liu , Yuichiro Iwashita , Soichiro Nakako , Masakazu Iwamura , Koichi Kise

Electronic Medical Records (EMRs), while integral to modern healthcare, present challenges for clinical reasoning and diagnosis due to their complexity and information redundancy. To address this, we proposed medIKAL (Integrating Knowledge…

Computation and Language · Computer Science 2025-02-18 Mingyi Jia , Junwen Duan , Yan Song , Jianxin Wang

Artificial intelligence (AI) has demonstrated significant potential in transforming healthcare through the analysis and modeling of electronic health records (EHRs). However, the inherent heterogeneity, temporal irregularity, and…

Machine Learning · Computer Science 2025-07-18 Weijieying Ren , Jingxi Zhu , Zehao Liu , Tianxiang Zhao , Vasant Honavar

Knowledge graph (KG) embedding encodes the entities and relations from a KG into low-dimensional vector spaces to support various applications such as KG completion, question answering, and recommender systems. In real world, knowledge…

Databases · Computer Science 2022-06-02 Tianxing Wu , Arijit Khan , Melvin Yong , Guilin Qi , Meng Wang

In this paper we study the problem of predicting clinical diagnoses from textual Electronic Health Records (EHR) data. We show the importance of this problem in medical community and present comprehensive historical review of the problem…

Computation and Language · Computer Science 2020-09-29 Pavel Blinov , Manvel Avetisian , Vladimir Kokh , Dmitry Umerenkov , Alexander Tuzhilin

Deep learning-based predictive models, leveraging Electronic Health Records (EHR), are receiving increasing attention in healthcare. An effective representation of a patient's EHR should hierarchically encompass both the temporal…

Machine Learning · Computer Science 2024-05-08 Jiayuan Chen , Changchang Yin , Yuanlong Wang , Ping Zhang

A knowledge graph (KG) is a data structure which represents entities and relations as the vertices and edges of a directed graph with edge types. KGs are an important primitive in modern machine learning and artificial intelligence.…

Artificial Intelligence · Computer Science 2021-10-20 Michael R. Douglas , Michael Simkin , Omri Ben-Eliezer , Tianqi Wu , Peter Chin , Trung V. Dang , Andrew Wood

Electroencephalography (EEG) signals provide critical insights for applications in disease diagnosis and healthcare. However, the scarcity of labeled EEG data poses a significant challenge. Foundation models offer a promising solution by…

Machine Learning · Computer Science 2025-02-25 Limin Wang , Toyotaro Suzumura , Hiroki Kanezashi

Knowledge graphs are powerful tools for representing and organising complex biomedical data. Several knowledge graph embedding algorithms have been proposed to learn from and complete knowledge graphs. However, a recent study demonstrates…

Predicting missing facts in a knowledge graph (KG) is a crucial task in knowledge base construction and reasoning, and it has been the subject of much research in recent works using KG embeddings. While existing KG embedding approaches…

Computation and Language · Computer Science 2020-10-09 Xuelu Chen , Muhao Chen , Changjun Fan , Ankith Uppunda , Yizhou Sun , Carlo Zaniolo

Knowledge graphs (KGs) play a crucial role in many applications, such as question answering, but incompleteness is an urgent issue for their broad application. Much research in knowledge graph completion (KGC) has been performed to resolve…

Artificial Intelligence · Computer Science 2023-01-10 Yinyu Lan , Shizhu He , Kang Liu , Jun Zhao

Accurate and explainable health event predictions are becoming crucial for healthcare providers to develop care plans for patients. The availability of electronic health records (EHR) has enabled machine learning advances in providing these…

Machine Learning · Computer Science 2021-05-18 Chang Lu , Chandan K. Reddy , Prithwish Chakraborty , Samantha Kleinberg , Yue Ning

The objective of this work is to develop an Electronic Medical Record (EMR) data processing tool that confers clinical context to Machine Learning (ML) algorithms for error handling, bias mitigation and interpretability. We present…

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