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The COVID-19 pandemic is spreading rapidly around the world, causing countries to impose lockdowns and efforts to develop vaccines on a global scale. However, human-to-animal and animal-to-human transmission cannot be ignored, as severe…

Populations and Evolution · Quantitative Biology 2024-08-20 Zi Hian Tan , Kian Yan Yong , Jian-Jun Shu

Detecting personally identifiable information (PII) in user queries is critical for ensuring privacy in question-answering systems. Current approaches mainly redact all PII, disregarding the fact that some of them may be contextually…

Cryptography and Security · Computer Science 2026-02-11 Mariia Ponomarenko , Sepideh Abedini , Masoumeh Shafieinejad , D. B. Emerson , Shubhankar Mohapatra , Xi He

Software is prone to security vulnerabilities. Program analysis tools to detect them have limited effectiveness in practice due to their reliance on human labeled specifications. Large language models (or LLMs) have shown impressive code…

Cryptography and Security · Computer Science 2025-04-08 Ziyang Li , Saikat Dutta , Mayur Naik

Spatio-temporal modeling of wireless access latency is of great importance for connected-vehicular systems. The quality of the molded results rely heavily on the number and quality of samples which can vary significantly due to the sensor…

Signal Processing · Electrical Eng. & Systems 2020-03-17 Rong Xia , Yong Xiao , Yingyu Li , Marwan Krunz , Dusit Niyato

Genomic surveillance of SARS-CoV-2 has been instrumental in tracking the spread and evolution of the virus during the pandemic. The availability of SARS-CoV-2 molecular sequences isolated from infected individuals, coupled with phylodynamic…

Applications · Statistics 2021-08-31 Lorenzo Cappello , Jaehee Kim , Sifan Liu , Julia A. Palacios

Exploring data requires a fast feedback loop from the analyst to the system, with a latency below about 10 seconds because of human cognitive limitations. When data becomes large or analysis becomes complex, sequential computations can no…

Human-Computer Interaction · Computer Science 2016-07-19 Jean-Daniel Fekete , Romain Primet

Summary: The CoV-Spectrum website supports the identification of new SARS-CoV-2 variants of concern and the tracking of known variants. Its flexible amino acid and nucleotide mutation search allows querying of variants before they are…

Populations and Evolution · Quantitative Biology 2021-12-28 Chaoran Chen , Sarah Nadeau , Michael Yared , Philippe Voinov , Ning Xie , Cornelius Roemer , Tanja Stadler

Regular path queries (RPQs) in graph databases are bottlenecked by the memory wall. Emerging processing-in-memory (PIM) technologies offer a promising solution to dispatch and execute path matching tasks in parallel within PIM modules. We…

Databases · Computer Science 2024-03-18 Ruoyan Ma , Shengan Zheng , Guifeng Wang , Jin Pu , Yifan Hua , Wentao Wang , Linpeng Huang

Effective decision-making for crisis mitigation increasingly relies on visualisation of large amounts of data. While interactive dashboards are more informative than static visualisations, their development is far more time-demanding and…

Human-Computer Interaction · Computer Science 2021-07-28 Raphael Lepuschitz , Niklas Stoehr

Large language models (LLMs) are widely used for natural language understanding and text generation. An LLM model relies on a time-consuming step called LLM decoding to generate output tokens. Several prior works focus on improving the…

Hardware Architecture · Computer Science 2025-02-28 Yintao He , Haiyu Mao , Christina Giannoula , Mohammad Sadrosadati , Juan Gómez-Luna , Huawei Li , Xiaowei Li , Ying Wang , Onur Mutlu

Indexing is an effective way to support efficient query processing in large databases. Recently the concept of learned index, which replaces or complements traditional index structures with machine learning models, has been actively…

Databases · Computer Science 2022-08-01 Yao Tian , Tingyun Yan , Xi Zhao , Kai Huang , Xiaofang Zhou

Recent progress in Medical Artificial Intelligence (AI) has delivered systems that can reach clinical expert level performance. However, such systems tend to demonstrate sub-optimal "out-of-distribution" performance when evaluated in…

This paper introduces a lossless data compression competition that benchmarks solutions (computer programs) by the compressed size of the 44,981 concatenated SARS-CoV-2 sequences, with a total uncompressed size of 1,339,868,341 bytes. The…

Databases · Computer Science 2020-12-23 Innar Liiv

Interrogation of biological pathways is an integral part of omics data analysis. Large language models (LLMs) enable the generation of custom pathways and gene sets tailored to specific scientific questions. These targeted sets are…

Bioinformatics web servers are critical resources in modern biomedical research, facilitating interactive exploration of datasets through custom-built interfaces with rich visualization capabilities. However, this human-centric design…

Other Quantitative Biology · Quantitative Biology 2026-02-25 Matthias Flotho , Ian Ferenc Diks , Philipp Flotho , Leidy-Alejandra G. Molano , Pascal Hirsch , Andreas Keller

The availability of open-source molecular simulation software packages allows scientists and engineers to focus on running and analyzing simulations without having to write, parallelize, and validate their own simulation software. While…

Computational Physics · Physics 2025-10-03 Simon Gravelle , Cecilia M. S. Alvares , Jacob R. Gissinger , Axel Kohlmeyer

Personal data collected at scale promises to improve decision-making and accelerate innovation. However, sharing and using such data raises serious privacy concerns. A promising solution is to produce synthetic data, artificial records to…

Tandem repeats in proteins identification, classification and curation is a complex process that requires manual processing from experts, processing power and time. There are recent and relevant advances applying machine learning for…

Software Engineering · Computer Science 2024-07-11 Manuel Bezerra-Brandao , Ronaldo Romario Tunque Cahui , Layla Hirsh

Scientists increasingly rely on Python tools to perform scalable distributed memory array operations using rich, NumPy-like expressions. However, many of these tools rely on dynamic schedulers optimized for abstract task graphs, which often…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-07-14 Melih Elibol , Vinamra Benara , Samyu Yagati , Lianmin Zheng , Alvin Cheung , Michael I. Jordan , Ion Stoica

Motivation: Data volumes generated by next-generation sequencing technolo- gies is now a major concern, both for storage and transmission. This triggered the need for more efficient methods than general purpose compression tools, such as…

Data Structures and Algorithms · Computer Science 2014-12-19 Gaëtan Benoit , Claire Lemaitre , Dominique Lavenier , Guillaume Rizk