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Rapid development of modern sequencing platforms enabled an unprecedented growth of protein families databases. The abundance of sets composed of hundreds of thousands sequences is a great challenge for multiple sequence alignment…

Genomics · Quantitative Biology 2017-03-03 Sebastin Deorowicz , Agnieszka Debudaj-Grabysz , Adam Gudys

The research interest in specialized hardware accelerators for deep neural networks (DNN) spikes recently owing to their superior performance and efficiency. However, today's DNN accelerators primarily focus on accelerating specific…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-06-11 Cong Guo , Yangjie Zhou , Jingwen Leng , Yuhao Zhu , Zidong Du , Quan Chen , Chao Li , Bin Yao , Minyi Guo

The Multilevel Fast Multipole Algorithm (MLFMA) has known applications in scientific modeling in the fields of telecommunications, physics, mechanics, and chemistry. Accelerating calculation of far-field using GPUs and GPU clusters for…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-03-05 Morteza Sadeghi , Abdolreza Torabi

We present Fast Approximate Minimum Spanning Tree (FAMST), a novel algorithm that addresses the computational challenges of constructing Minimum Spanning Trees (MSTs) for large-scale and high-dimensional datasets. FAMST utilizes a…

Data Structures and Algorithms · Computer Science 2025-07-22 Mahmood K. M. Almansoori , Miklos Telek

The constant growth of DNNs makes them challenging to implement and run efficiently on traditional compute-centric architectures. Some accelerators have attempted to add more compute units and on-chip buffers to solve the memory wall…

Hardware Architecture · Computer Science 2023-10-30 Bahareh Khabbazan , Marc Riera , Antonio González

Traditional digital implementations of neural accelerators are limited by high power and area overheads, while analog and non-CMOS implementations suffer from noise, device mismatch, and reliability issues. This paper introduces a CMOS…

Today's big data clusters based on the MapReduce paradigm are capable of executing analysis jobs with multiple priorities, providing differential latency guarantees. Traces from production systems show that the latency advantage of…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-09-17 Robert Birke , Isabelly Rocha , Juan Perez , Valerio Schiavoni , Pascal Felber , Lydia Y. Chen

Efficient execution of parameter sensitivity analysis (SA) is critical to allow for its routinely use. The pathology image processing application investigated in this work processes high-resolution whole-slide cancer tissue images from…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-11-01 Eduardo Scartezini , Willian Barreiros , Tahsin Kurc , Jun Kong , Alba C. M. A. Melo , Joel Saltz , George Teodoro

Time series forecasting plays an increasingly important role in modern business decisions. In today's data-rich environment, people often aim to choose the optimal forecasting model for their data. However, identifying the optimal model…

Applications · Statistics 2021-12-17 Xixi Li , Fotios Petropoulos , Yanfei Kang

In this article, we investigate the impact of architectural parameters of array-based DNN accelerators on accelerator's energy consumption and performance in a wide variety of network topologies. For this purpose, we have developed a tool…

Hardware Architecture · Computer Science 2022-06-28 Mohammad Ali Maleki , Mehdi Kamal , Ali Afzali-Kusha

Genome sequence analysis has enabled significant advancements in medical and scientific areas such as personalized medicine, outbreak tracing, and the understanding of evolution. Unfortunately, it is currently bottlenecked by the…

Recent innovations in Transformer-based large language models have significantly advanced the field of general-purpose neural language understanding and generation. With billions of trainable parameters, deployment of these large models…

Hardware Architecture · Computer Science 2024-10-11 Haocheng Xu , Faraz Tahmasebi , Ye Qiao , Hongzheng Tian , Hyoukjun Kwon , Sitao Huang

Accelerators for sparse matrix multiplication are important components in emerging systems. In this paper, we study the main challenges of accelerating Sparse Matrix Multiplication (SpMM). For the situations that data is not stored in the…

Hardware Architecture · Computer Science 2019-06-04 Pareesa Ameneh Golnari , Sharad Malik

Time series analysis plays a critical role in numerous applications, supporting tasks such as forecasting, classification, anomaly detection, and imputation. In this work, we present the time series pattern machine (TSPM), a model designed…

Machine Learning · Computer Science 2025-05-20 Shiyu Wang , Jiawei Li , Xiaoming Shi , Zhou Ye , Baichuan Mo , Wenze Lin , Shengtong Ju , Zhixuan Chu , Ming Jin

Many studies estimate energy consumption using proxy metrics like memory usage, FLOPs, and inference latency, with the assumption that reducing these metrics will also lower energy consumption in neural networks. This paper, however, takes…

Machine Learning · Computer Science 2025-04-14 Hoang-Loc La , Phuong Hoai Ha

Hierarchical Navigable Small World (HNSW) has demonstrated impressive accuracy and low latency for high-dimensional nearest neighbor searches. However, its high computational demands and irregular, large-volume data access patterns present…

Hardware Architecture · Computer Science 2026-02-24 Zheng Li , Guangyi Zeng , Paul Delestrac , Enyi Yao , Simei Yang

Hidden Markov models (HMMs) are characterized by an unobservable Markov chain and an observable process -- a noisy version of the hidden chain. Decoding the original signal from the noisy observations is one of the main goals in nearly all…

Methodology · Statistics 2026-05-19 Alexandre Mösching , Housen Li , Axel Munk

The digitisation of industry provides a plethora of novel applications that increase flexibility and reduce setup and maintenance time as well as cost. Furthermore, novel use cases are created by the digitisation of industry, commonly known…

Cryptography and Security · Computer Science 2020-07-20 Simon D Duque Anton , Hans Dieter Schotten

The increasing complexity and diversity of hardware accelerators in modern computing systems demand flexible, low-overhead program analysis tools. We present PASTA, a low-overhead and modular Program AnalysiS Tool Framework for…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-26 Mao Lin , Hyeran Jeon , Keren Zhou

With the growing number of data-intensive workloads, GPU, which is the state-of-the-art single-instruction-multiple-thread (SIMT) processor, is hindered by the memory bandwidth wall. To alleviate this bottleneck, previously proposed…

Hardware Architecture · Computer Science 2021-03-12 Xinfeng Xie , Peng Gu , Yufei Ding , Dimin Niu , Hongzhong Zheng , Yuan Xie