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Transformers have achieved remarkable success across multiple fields, yet their impact on 3D medical image segmentation remains limited with convolutional networks still dominating major benchmarks. In this work, (A) we analyze current…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Tassilo Wald , Saikat Roy , Fabian Isensee , Constantin Ulrich , Sebastian Ziegler , Dasha Trofimova , Raphael Stock , Michael Baumgartner , Gregor Köhler , Klaus Maier-Hein

Medical image segmentation requires models that preserve fine anatomical boundaries while remaining practical for clinical deployment. Transformers capture long-range dependencies but incur quadratic attention cost, whereas CNNs are…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 Hongbo Zheng , Afshin Bozorgpour , Dorit Merhof , Minjia Zhang

Polygonal meshes have become the standard for discretely approximating 3D shapes, thanks to their efficiency and high flexibility in capturing non-uniform shapes. This non-uniformity, however, leads to irregularity in the mesh structure,…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Giuseppe Vecchio , Luca Prezzavento , Carmelo Pino , Francesco Rundo , Simone Palazzo , Concetto Spampinato

U-Nets have achieved tremendous success in medical image segmentation. Nevertheless, it may suffer limitations in global (long-range) contextual interactions and edge-detail preservation. In contrast, Transformer has an excellent ability to…

Computer Vision and Pattern Recognition · Computer Science 2022-06-03 Nan Wang , Shaohui Lin , Xiaoxiao Li , Ke Li , Yunhang Shen , Yue Gao , Lizhuang Ma

Brain tissue segmentation has demonstrated great utility in quantifying MRI data through Voxel-Based Morphometry and highlighting subtle structural changes associated with various conditions within the brain. However, manual segmentation is…

Image and Video Processing · Electrical Eng. & Systems 2023-02-02 Vishwanatha M. Rao , Zihan Wan , Soroush Arabshahi , David J. Ma , Pin-Yu Lee , Ye Tian , Xuzhe Zhang , Andrew F. Laine , Jia Guo

Segmenting biomarkers in medical images is crucial for various biotech applications. Despite advances, Transformer and CNN based methods often struggle with variations in staining and morphology, limiting feature extraction. In medical…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Saad Wazir , Daeyoung Kim

In medical image segmentation, specialized computer vision techniques, notably transformers grounded in attention mechanisms and residual networks employing skip connections, have been instrumental in advancing performance. Nonetheless,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Fuchen Zheng , Xuhang Chen , Weihuang Liu , Haolun Li , Yingtie Lei , Jiahui He , Chi-Man Pun , Shounjun Zhou

Identifying biomarkers in medical images is vital for a wide range of biotech applications. However, recent Transformer and CNN based methods often struggle with variations in morphology and staining, which limits their feature extraction…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Saad Wazir , Daeyoung Kim

Medical image segmentation is pivotal in healthcare, enhancing diagnostic accuracy, informing treatment strategies, and tracking disease progression. This process allows clinicians to extract critical information from visual data, enabling…

Image and Video Processing · Electrical Eng. & Systems 2024-10-31 Ovais Iqbal Shah , Danish Raza Rizvi , Aqib Nazir Mir

In recent years, significant progress has been made in the medical image analysis domain using convolutional neural networks (CNNs). In particular, deep neural networks based on a U-shaped architecture (UNet) with skip connections have been…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Vamsi Krishna Vasa , Wenhui Zhu , Xiwen Chen , Peijie Qiu , Xuanzhao Dong , Yalin Wang

Medical image segmentation is an essential prerequisite for developing healthcare systems, especially for disease diagnosis and treatment planning. On various medical image segmentation tasks, the u-shaped architecture, also known as U-Net,…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Jieneng Chen , Yongyi Lu , Qihang Yu , Xiangde Luo , Ehsan Adeli , Yan Wang , Le Lu , Alan L. Yuille , Yuyin Zhou

In the realm of medical diagnostics, rapid advancements in Artificial Intelligence (AI) have significantly yielded remarkable improvements in brain tumor segmentation. Encoder-Decoder architectures, such as U-Net, have played a…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Eyad Gad , Seif Soliman , M. Saeed Darweesh

Multi-organ segmentation is one of most successful applications of deep learning in medical image analysis. Deep convolutional neural nets (CNNs) have shown great promise in achieving clinically applicable image segmentation performance on…

Image and Video Processing · Electrical Eng. & Systems 2020-12-18 Hao Tang , Xingwei Liu , Kun Han , Shanlin Sun , Narisu Bai , Xuming Chen , Huang Qian , Yong Liu , Xiaohui Xie

Transformer-based architectures have advanced medical image analysis by effectively modeling long-range dependencies, yet they often struggle in 3D settings due to substantial memory overhead and insufficient capture of fine-grained local…

Medical image segmentation faces challenges due to variations in anatomical structures. While convolutional neural networks (CNNs) effectively capture local features, they struggle with modeling long-range dependencies. Transformers…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Lalit Maurya , Honghai Liu , Reyer Zwiggelaar

3D image segmentation is one of the most important and ubiquitous problems in medical image processing. It provides detailed quantitative analysis for accurate disease diagnosis, abnormal detection, and classification. Currently deep…

Computer Vision and Pattern Recognition · Computer Science 2019-06-19 Zhenxi Zhang , Jie Li , Zhusi Zhong , Zhicheng Jiao , Xinbo Gao

Medical image segmentation is an important step in medical image analysis, especially as a crucial prerequisite for efficient disease diagnosis and treatment. The use of deep learning for image segmentation has become a prevalent trend. The…

Image and Video Processing · Electrical Eng. & Systems 2023-08-11 Wenjian Yao , Jiajun Bai , Wei Liao , Yuheng Chen , Mengjuan Liu , Yao Xie

Transformers have emerged as the state-of-the-art architecture in medical image registration, outperforming convolutional neural networks (CNNs) by addressing their limited receptive fields and overcoming gradient instability in deeper…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Abu Zahid Bin Aziz , Mokshagna Sai Teja Karanam , Tushar Kataria , Shireen Y. Elhabian

Since their emergence, Convolutional Neural Networks (CNNs) have made significant strides in medical image analysis. However, the local nature of the convolution operator may pose a limitation for capturing global and long-range…

Image and Video Processing · Electrical Eng. & Systems 2024-04-01 Abdul Rehman Khan , Asifullah Khan

The convolutional neural network-based methods have become more and more popular for medical image segmentation due to their outstanding performance. However, they struggle with capturing long-range dependencies, which are essential for…

Image and Video Processing · Electrical Eng. & Systems 2024-01-30 Hongkun Sun , Jing Xu , Yuping Duan